α-Mangostin, a xanthone from mangosteen fruit, promotes cell cycle arrest in prostate cancer and decreases xenograft tumor growth - Wikidata - awgldk - TriplyDB

α-Mangostin, a xanthone from mangosteen fruit, promotes cell cycle arrest in prostate cancer and decreases xenograft tumor growth

α-Mangostin, a xanthone from mangosteen fruit, promotes cell cycle arrest in prostate cancer and decreases xenograft tumor growth

http://www.wikidata.org/entity/Q39430033

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Efficient enzymatic systems for synthesis of novel α-mangostin glycosides exhibiting antibacterial activity against Gram-positive bacteria.Alpha-mangostin inhibits intracellular fatty acid synthase and induces apoptosis in breast cancer cells.Dietary α-mangostin, a xanthone from mangosteen fruit, exacerbates experimental colitis and promotes dysbiosis in mice.α-Mangostin: a dietary antioxidant derived from the pericarp of Garcinia mangostana L. inhibits pancreatic tumor growth in xenograft mouse model.In vitro and in vivo anti-colon cancer effects of Garcinia mangostana xanthones extract Biological activities and bioavailability of mangosteen xanthones: a critical review of the current evidence.Piperine, a Bioactive Component of Pepper Spice Exerts Therapeutic Effects on Androgen Dependent and Androgen Independent Prostate Cancer Cells Selective modulation of endoplasmic reticulum stress markers in prostate cancer cells by a standardized mangosteen fruit extract Rosemary (Rosmarinus officinalis) extract modulates CHOP/GADD153 to promote androgen receptor degradation and decreases xenograft tumor growth Intestinal microbial dysbiosis and colonic epithelial cell hyperproliferation by dietary α-mangostin is independent of mouse strain.High-throughput screen of natural product libraries for hsp90 inhibitors.α-Mangostin Improves Glucose Uptake and Inhibits Adipocytes Differentiation in 3T3-L1 Cells via PPARγ, GLUT4, and Leptin Expressions.Screening a Small Library of Xanthones for Antitumor Activity and Identification of a Hit Compound which Induces Apoptosis.Inhibition of Cell Proliferation in an NRAS Mutant Melanoma Cell Line by Combining Sorafenib and α-Mangostin.Garcinia dulcis Fruit Extract Induced Cytotoxicity and Apoptosis in HepG2 Liver Cancer Cell Line.Antitumor and apoptosis-inducing effects of α-mangostin extracted from the pericarp of the mangosteen fruit (Garcinia mangostana L.)in YD-15 tongue mucoepidermoid carcinoma cells The effect of gartanin, a naturally occurring xanthone in mangosteen juice, on the mTOR pathway, autophagy, apoptosis, and the growth of human urinary bladder cancer cell lines Anticancer compounds from plants.Polyphenols from the mangosteen (Garcinia mangostana) fruit for breast and prostate cancer.α-Mangostin Induces Apoptosis and Cell Cycle Arrest in Oral Squamous Cell Carcinoma Cell Anti-tumorigenicity of dietary α-mangostin in an HT-29 colon cell xenograft model and the tissue distribution of xanthones and their phase II metabolites.Synergic Effect of α-Mangostin on the Cytotoxicity of Cisplatin in a Cervical Cancer Model.Gartanin induces cell cycle arrest and autophagy and suppresses migration involving PI3K/Akt/mTOR and MAPK signalling pathway in human glioma cells.Mangiferin in cancer chemoprevention and treatment: pharmacokinetics and molecular targets.Isolation and structural modifications of ananixanthone from Calophyllum teysmannii and their cytotoxic activities.Beta-mangostin demonstrates apoptogenesis in murine leukaemia (WEHI-3) cells in vitro and in vivo Anti-proliferative properties of commercial Pelargonium sidoides tincture, with cell-cycle G0/G1 arrest and apoptosis in Jurkat leukaemia cells.α-Mangostin suppresses the viability and epithelial-mesenchymal transition of pancreatic cancer cells by downregulating the PI3K/Akt pathway.Altered mRNA expression related to the apoptotic effect of three xanthones on human melanoma SK-MEL-28 cell line.α-Mangostin induces mitochondrial dependent apoptosis in human hepatoma SK-Hep-1 cells through inhibition of p38 MAPK pathway.α-Mangostin: anti-inflammatory activity and metabolism by human cells Apoptosis induced by benzyl isothiocyanate in gefitinib-resistant lung cancer cells is associated with Akt/MAPK pathways and generation of reactive oxygen species.Alpha-mangostin suppresses MMP-2 and MMP-9 expression in head and neck squamous carcinoma cells.Beta-mangostin from Cratoxylum arborescens activates the intrinsic apoptosis pathway through reactive oxygen species with downregulation of the HSP70 gene in the HL60 cells associated with a G0/G1 cell-cycle arrest.Griffipavixanthone from Garcinia oblongifolia champ induces cell apoptosis in human non-small-cell lung cancer H520 cells in vitro.α, γ-Mangostins Induce Autophagy and Show Synergistic Effect with Gemcitabine in Pancreatic Cancer Cell Lines.Ormeloxifene Suppresses Prostate Tumor Growth and Metastatic Phenotypes via Inhibition of Oncogenic β-catenin Signaling and EMT Progression.Gartanin, an isoprenylated xanthone from the mangosteen fruit (Garcinia mangostana), is an androgen receptor degradation enhancer.Induction of Apoptosis and Inhibition of Epithelial Mesenchymal Transition by α-Mangostin in MG-63 Cell Lines.Synthetic α-mangostin dilaurate strongly suppresses wide-spectrum organ metastasis in a mouse model of mammary cancer.

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α-Mangostin, a xanthone from mangosteen fruit, promotes cell cycle arrest in prostate cancer and decreases xenograft tumor growth

http://www.wikidata.org/entity/Q39430033

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name

α-Mangostin, a xanthone from m ...... creases xenograft tumor growth

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α-Mangostin, a xanthone from m ...... reases xenograft tumor growth.

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α-Mangostin, a xanthone from m ...... creases xenograft tumor growth

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α-Mangostin, a xanthone from m ...... reases xenograft tumor growth.

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α-Mangostin, a xanthone from m ...... creases xenograft tumor growth

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α-Mangostin, a xanthone from m ...... reases xenograft tumor growth.

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α-Mangostin, a xanthone from m ...... creases xenograft tumor growth

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Amanda M Kohl

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Deeba N Syed

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Hasan Mukhtar

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Imtiaz A Siddiqui

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Jeremy J Johnson

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John T Rasmussen

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Sakina M Petiwala

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Vaqar M Adhami

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P2860

Crystal structure of human CDK4 in complex with a D-type cyclin

Antioxidant xanthones from the pericarp of Garcinia mangostana (Mangosteen)

Induction of apoptosis by xanthones from mangosteen in human leukemia cell lines.

Xanthones induce cell-cycle arrest and apoptosis in human colon cancer DLD-1 cells.

Medicinal properties of mangosteen (Garcinia mangostana).

Chemoprevention of mouse intestinal tumorigenesis by the cyclin-dependent kinase inhibitor SNS-032

Preferential target is mitochondria in alpha-mangostin-induced apoptosis in human leukemia HL60 cells.

Effect of Garcinia mangostana on inflammation caused by Propionibacterium acnes.

Carnosol: a promising anti-cancer and anti-inflammatory agent.

Garcinia mangostana L.: a phytochemical and pharmacological review.

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10.1093/CARCIN/BGR291

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