Reduction of misleading ("false") positive results in mammalian cell genotoxicity assays. I. Choice of cell type.
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State-of-the-art of 3D cultures (organs-on-a-chip) in safety testing and pathophysiologyGenetic toxicity assessment of engineered nanoparticles using a 3D in vitro skin model (EpiDerm™)Look back in anger - what clinical studies tell us about preclinical workRetrospective analysis of the mutagenicity/genotoxicity data of the cosmetic ingredients present on the Annexes of the Cosmetic EU legislation (2000-12).Genomic phenotyping by barcode sequencing broadly distinguishes between alkylating agents, oxidizing agents, and non-genotoxic agents, and reveals a role for aromatic amino acids in cellular recovery after quinone exposureThe Extended ToxTracker Assay Discriminates Between Induction of DNA Damage, Oxidative Stress, and Protein Misfolding.Factors affecting the in vitro micronucleus assay for evaluation of nanomaterials.Aerobic Bioremediation of PAH Contaminated Soil Results in Increased Genotoxicity and Developmental Toxicity.Genotoxic mode of action predictions from a multiplexed flow cytometric assay and a machine learning approach.Genotoxic mixtures and dissimilar action: concepts for prediction and assessmentPerformance of the in vitro transgene mutation assay in MutaMouse FE1 cells: Evaluation of nine misleading ("False") positive chemicals.In vitro genotoxicity of carcinogenic asarone isomers.Development of an in vitro PIG-A gene mutation assay in human cells.Complementarity of phosphorylated histones H2AX and H3 quantification in different cell lines for genotoxicity screening.Evaluation of genotoxicity using automated detection of γH2AX in metabolically competent HepaRG cells.Genotoxic capacity of Cd/Se semiconductor quantum dots with differing surface chemistriesAcute dosing and p53-deficiency promote cellular sensitivity to DNA methylating agents.An evaluation of US patent 2015065565 (A1) for a new class of SGLT2 inhibitors for treatment 1 of type II diabetes mellitus.Chromosome breakage induced by the genotoxic agents mitomycin C and cytosine arabinoside is concentration and p53 dependent.Performance of comet and micronucleus assays in metabolic competent HepaRG cells to predict in vivo genotoxicity.Validation of high-throughput genotoxicity assay screening using γH2AX in-cell western assay on HepG2 cells.The involvement of WT1 in the regulation of GADD45a in response to genotoxic stress.Advances in bumped kinase inhibitors for human and animal therapy for cryptosporidiosis.Automation of the in vitro micronucleus and chromosome aberration assay for the assessment of the genotoxicity of the particulate and gas-vapor phase of cigarette smoke.Investigating the Generalizability of the MultiFlow® DNA Damage Assay and Several Companion Machine Learning Models with a Set of 103 Diverse Test Chemicals.Scientific Opinion on the re-evaluation of propyl gallate (E 310) as a food additiveSafety of ethyl acrylate to be used as flavouringClassification of in vitro genotoxicants using a novel multiplexed biomarker assay compared to the flow cytometric micronucleus test.A combination of in vitro comet assay and micronucleus test using human lymphoblastoid TK6 cells.An integrative test strategy for cancer hazard identification.Evaluation of the LacZ reporter assay in cryopreserved primary hepatocytes for In vitro genotoxicity testing.An updated review of the genotoxicity of respirable crystalline silica.Proliferating primary hepatocytes from the pUR288 lacZ plasmid mouse are valuable tools for genotoxicity assessment in vitro
P2860
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P2860
Reduction of misleading ("false") positive results in mammalian cell genotoxicity assays. I. Choice of cell type.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年学术文章
@wuu
2011年学术文章
@zh-cn
2011年学术文章
@zh-hans
2011年学术文章
@zh-my
2011年学术文章
@zh-sg
2011年學術文章
@yue
2011年學術文章
@zh
2011年學術文章
@zh-hant
name
Reduction of misleading ("fals ...... ssays. I. Choice of cell type.
@en
Reduction of misleading
@nl
type
label
Reduction of misleading ("fals ...... ssays. I. Choice of cell type.
@en
Reduction of misleading
@nl
prefLabel
Reduction of misleading ("fals ...... ssays. I. Choice of cell type.
@en
Reduction of misleading
@nl
P2093
P1433
P1476
Reduction of misleading ("fals ...... ssays. I. Choice of cell type.
@en
P2093
David Kirkland
Jamie Young
Katie Smith
Laura Jeffrey
Paul Carmichael
Paul Fowler
Stefan Pfuhler
P356
10.1016/J.MRGENTOX.2011.10.014
P407
P577
2011-11-26T00:00:00Z