Selective cytotoxicity of rhodium metalloinsertors in mismatch repair-deficient cells.
about
The path for metal complexes to a DNA targetAn unusual ligand coordination gives rise to a new family of rhodium metalloinsertors with improved selectivity and potency.A monofunctional platinum complex coordinated to a rhodium metalloinsertor selectively binds mismatched DNA in the minor groove.Targeting DNA Mismatches with Rhodium Metalloinsertors.A metal-based inhibitor of NEDD8-activating enzyme.An inducible, isogenic cancer cell line system for targeting the state of mismatch repair deficiency.Cell-selective biological activity of rhodium metalloinsertors correlates with subcellular localizationFinding needles in a basestack: recognition of mismatched base pairs in DNA by small molecules.The effect of LNA nucleobases as enhancers for the binding of amiloride to an abasic site in DNA/DNA and DNA/RNA duplexes.Luminescence of [Ru(bpy)2(dppz)]2+ bound to RNA mismatches.Necroptosis-inducing rhenium(V) oxo complexes.A platinum complex that binds non-covalently to DNA and induces cell death via a different mechanism than cisplatin.Assessing the intracellular fate of rhodium(ii) complexes.[Ru(Me4phen)2dppz](2+), a Light Switch for DNA MismatchesBiological effects of simple changes in functionality on rhodium metalloinsertors.Construction and application of a Rh-Pt DNA metalloinsertor conjugate.Targeted Chemotherapy with Metal Complexes.Rhodium metalloinsertor binding generates a lesion with selective cytotoxicity for mismatch repair-deficient cells.A chemical-biological evaluation of rhodium(I) N-heterocyclic carbene complexes as prospective anticancer drugs.A Ruthenium(II) Complex as a Luminescent Probe for DNA Mismatches and Abasic Sites.
P2860
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P2860
Selective cytotoxicity of rhodium metalloinsertors in mismatch repair-deficient cells.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年学术文章
@wuu
2011年学术文章
@zh-cn
2011年学术文章
@zh-hans
2011年学术文章
@zh-my
2011年学术文章
@zh-sg
2011年學術文章
@yue
2011年學術文章
@zh
2011年學術文章
@zh-hant
name
Selective cytotoxicity of rhodium metalloinsertors in mismatch repair-deficient cells.
@en
Selective cytotoxicity of rhodium metalloinsertors in mismatch repair-deficient cells.
@nl
type
label
Selective cytotoxicity of rhodium metalloinsertors in mismatch repair-deficient cells.
@en
Selective cytotoxicity of rhodium metalloinsertors in mismatch repair-deficient cells.
@nl
prefLabel
Selective cytotoxicity of rhodium metalloinsertors in mismatch repair-deficient cells.
@en
Selective cytotoxicity of rhodium metalloinsertors in mismatch repair-deficient cells.
@nl
P2093
P2860
P356
P1433
P1476
Selective cytotoxicity of rhodium metalloinsertors in mismatch repair-deficient cells.
@en
P2093
Alexis C Komor
Jacqueline K Barton
Russell J Ernst
P2860
P304
10919-10928
P356
10.1021/BI2015822
P407
P577
2011-11-21T00:00:00Z