EGFR signaling upregulates expression of microsomal prostaglandin E synthase-1 in cancer cells leading to enhanced tumorigenicity.
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Pharmacological inhibition of microsomal prostaglandin E synthase-1 suppresses epidermal growth factor receptor-mediated tumor growth and angiogenesisPGE2/EP3/SRC signaling induces EGFR nuclear translocation and growth through EGFR ligands release in lung adenocarcinoma cells.COX/mPGES-1/PGE2 pathway depicts an inflammatory-dependent high-risk neuroblastoma subset.mPGES-1 in prostate cancer controls stemness and amplifies epidermal growth factor receptor-driven oncogenicity.Kruppel-like factor 5 transcription factor promotes microsomal prostaglandin E2 synthase 1 gene transcription in breast cancerLinking microsomal prostaglandin E Synthase-1/PGE-2 pathway with miR-15a and -186 expression: Novel mechanism of VEGF modulation in prostate cancerHydroxytyrosol, a product from olive oil, reduces colon cancer growth by enhancing epidermal growth factor receptor degradation.Cyclooxygenase 2 in liver dysfunction and carcinogenesis: Facts and perspectives.Inhibition of EGR1 inhibits glioma proliferation by targeting CCND1 promoter.PGE2 mediates EGFR internalization and nuclear translocation via caveolin endocytosis promoting its transcriptional activity and proliferation in human NSCLC cells.
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P2860
EGFR signaling upregulates expression of microsomal prostaglandin E synthase-1 in cancer cells leading to enhanced tumorigenicity.
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2011 nî lūn-bûn
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name
EGFR signaling upregulates exp ...... ng to enhanced tumorigenicity.
@en
EGFR signaling upregulates exp ...... ng to enhanced tumorigenicity.
@nl
type
label
EGFR signaling upregulates exp ...... ng to enhanced tumorigenicity.
@en
EGFR signaling upregulates exp ...... ng to enhanced tumorigenicity.
@nl
prefLabel
EGFR signaling upregulates exp ...... ng to enhanced tumorigenicity.
@en
EGFR signaling upregulates exp ...... ng to enhanced tumorigenicity.
@nl
P2093
P2860
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EGFR signaling upregulates exp ...... ng to enhanced tumorigenicity.
@en
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A Giachetti
E Terzuoli
M A Iñiguez
P2860
P2888
P304
P356
10.1038/ONC.2011.503
P407
P577
2011-11-14T00:00:00Z