The Kinetic Stability of a Full-Length Antibody Light Chain Dimer Determines whether Endoproteolysis Can Release Amyloidogenic Variable Domains
about
Heat-induced native dimerization prevents amyloid formation by variable domain from immunoglobulin light-chain REI.Incomplete Refolding of Antibody Light Chains to Non-Native, Protease-Sensitive Conformations Leads to Aggregation: A Mechanism of Amyloidogenesis in Patients?Concurrent structural and biophysical traits link with immunoglobulin light chains amyloid propensity.In vitro co-expression of human amyloidogenic immunoglobulin light and heavy chain proteins: a relevant cell-based model of AL amyloidosis.Recent advances in understanding and treating immunoglobulin light chain amyloidosis
P2860
The Kinetic Stability of a Full-Length Antibody Light Chain Dimer Determines whether Endoproteolysis Can Release Amyloidogenic Variable Domains
description
2016 nî lūn-bûn
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2016年の論文
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2016年学术文章
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2016年学术文章
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2016年学术文章
@zh-hans
2016年学术文章
@zh-my
2016年学术文章
@zh-sg
2016年學術文章
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2016年學術文章
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2016年學術文章
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name
The Kinetic Stability of a Ful ...... Amyloidogenic Variable Domains
@en
The Kinetic Stability of a Ful ...... myloidogenic Variable Domains.
@nl
type
label
The Kinetic Stability of a Ful ...... Amyloidogenic Variable Domains
@en
The Kinetic Stability of a Ful ...... myloidogenic Variable Domains.
@nl
prefLabel
The Kinetic Stability of a Ful ...... Amyloidogenic Variable Domains
@en
The Kinetic Stability of a Ful ...... myloidogenic Variable Domains.
@nl
P2860
P1476
The Kinetic Stability of a Ful ...... Amyloidogenic Variable Domains
@en
P2860
P304
P356
10.1016/J.JMB.2016.08.021
P407
P577
2016-08-26T00:00:00Z