A novel role for helix 12 of retinoid X receptor in regulating repression. - Wikidata - awgldk - TriplyDB

A novel role for helix 12 of retinoid X receptor in regulating repression.

A novel role for helix 12 of retinoid X receptor in regulating repression.

http://www.wikidata.org/entity/Q39447809

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CIA, a novel estrogen receptor coactivator with a bifunctional nuclear receptor interacting determinant Nuclear receptor corepressors ERbeta Binds N-CoR in the Presence of Estrogens via an LXXLL-like Motif in the N-CoR C-terminus Structural basis for autorepression of retinoid X receptor by tetramer formation and the AF-2 helix The structural basis for the specificity of retinoid-X receptor-selective agonists: new insights into the role of helix H12 A unique secondary-structure switch controls constitutive gene repression by retinoic acid receptor Structural Basis for Retinoic X Receptor Repression on the Tetramer Nuclear receptor Rev-erbalpha: a heme receptor that coordinates circadian rhythm and metabolism Glucocorticoid signaling is perturbed by the atypical orphan receptor and corepressor SHP Hydrogen/deuterium exchange reveals distinct agonist/partial agonist receptor dynamics within vitamin D receptor/retinoid X receptor heterodimer One- plus two-hybrid system, a novel yeast genetic selection for specific missense mutations disrupting protein/protein interactions.The CoRNR motif controls the recruitment of corepressors by nuclear hormone receptors.Characterization of the repressor function of the nuclear orphan receptor retinoid receptor-related testis-associated receptor/germ cell nuclear factor.Specific structural motifs determine TRAP220 interactions with nuclear hormone receptors.Interactions that determine the assembly of a retinoid X receptor/corepressor complex.Ligand-dependent contribution of RXRbeta to cholesterol homeostasis in Sertoli cells.A structural model of the constitutive androstane receptor defines novel interactions that mediate ligand-independent activity Analysis of agonist and antagonist effects on thyroid hormone receptor conformation by hydrogen/deuterium exchange.The tailless nuclear receptor acts as a dedicated repressor in the early Drosophila embryo Aberrant corepressor interactions implicated in PML-RAR(alpha) and PLZF-RAR(alpha) leukemogenesis reflect an altered recruitment and release of specific NCoR and SMRT splice variants.Genetic and pharmacological evidence that a retinoic acid cannot be the RXR-activating ligand in mouse epidermis keratinocytes.The optimal corepressor function of nuclear receptor corepressor (NCoR) for peroxisome proliferator-activated receptor γ requires G protein pathway suppressor 2.Mechanism of corepressor binding and release from nuclear hormone receptors.SMRTε, a corepressor variant, interacts with a restricted subset of nuclear receptors, including the retinoic acid receptors α and β Structural mechanism for signal transduction in RXR nuclear receptor heterodimers.Estrogen signaling multiple pathways to impact gene transcription.The androgen receptor and its use in biological assays: looking toward effect-based testing and its applications.Alternative mRNA splicing of SMRT creates functional diversity by generating corepressor isoforms with different affinities for different nuclear receptors Vitamin D-dependent recruitment of corepressors to vitamin D/retinoid X receptor heterodimers Molecular adaptation and resilience of the insect's nuclear receptor USP Determinants of CoRNR-dependent repression complex assembly on nuclear hormone receptors.Ligand-dependent degradation of retinoid X receptors does not require transcriptional activity or coactivator interactions.Competitive cofactor recruitment by orphan receptor hepatocyte nuclear factor 4alpha1: modulation by the F domain.Retinoid X receptor alpha (RXRalpha) helix 12 plays an inhibitory role in the recruitment of the p160 co-activators by unliganded RXRalpha/retinoic acid receptor alpha heterodimers.A permissive retinoid X receptor/thyroid hormone receptor heterodimer allows stimulation of prolactin gene transcription by thyroid hormone and 9-cis-retinoic acid.A dominant negative PPARgamma mutant shows altered cofactor recruitment and inhibits adipogenesis in 3T3-L1 cells.Nuclear receptor corepressor-dependent repression of peroxisome-proliferator-activated receptor delta-mediated transactivation.T0070907, a selective ligand for peroxisome proliferator-activated receptor gamma, functions as an antagonist of biochemical and cellular activities.The tamoxifen-responsive estrogen receptor alpha mutant D351Y shows reduced tamoxifen-dependent interaction with corepressor complexes.Reporter cell lines are useful tools for monitoring biological activity of nuclear receptor ligands.

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P2860

A novel role for helix 12 of retinoid X receptor in regulating repression.

http://www.wikidata.org/entity/Q39447809

description

1999 nî lūn-bûn

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1999年の論文

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1999年学术文章

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1999年学术文章

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1999年学术文章

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1999年学术文章

@zh-my

1999年学术文章

@zh-sg

1999年學術文章

@yue

1999年學術文章

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1999年學術文章

@zh-hant

name

A novel role for helix 12 of retinoid X receptor in regulating repression.

@en

A novel role for helix 12 of retinoid X receptor in regulating repression.

@nl

type

label

A novel role for helix 12 of retinoid X receptor in regulating repression.

@en

A novel role for helix 12 of retinoid X receptor in regulating repression.

@nl

prefLabel

A novel role for helix 12 of retinoid X receptor in regulating repression.

@en

A novel role for helix 12 of retinoid X receptor in regulating repression.

@nl

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Molecular and Cellular Biology

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A novel role for helix 12 of retinoid X receptor in regulating repression.

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J Zhang

http://www.w3.org/2001/XMLSchema#string

M A Lazar

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X Hu

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P2860

Ligand-independent repression by the thyroid hormone receptor mediated by a nuclear receptor co-repressor

LXR, a nuclear receptor that defines a distinct retinoid response pathway

ETO, a target of t(8;21) in acute leukemia, interacts with the N-CoR and mSin3 corepressors

A transferable silencing domain is present in the thyroid hormone receptor, in the v-erbA oncogene product and in the retinoic acid receptor

The tau 4 activation domain of the thyroid hormone receptor is required for release of a putative corepressor(s) necessary for transcriptional silencing

Cloning and characterization of a corepressor and potential component of the nuclear hormone receptor repression complex

ETO, fusion partner in t(8;21) acute myeloid leukemia, represses transcription by interaction with the human N-CoR/mSin3/HDAC1 complex

Crystal structure of the RAR-gamma ligand-binding domain bound to all-trans retinoic acid

Structural determinants of nuclear receptor assembly on DNA direct repeats

Crystal structure of the ligand-binding domain of the human nuclear receptor RXR-alpha

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10.1128/MCB.19.9.6448

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