Modulation of transcriptional activation and coactivator interaction by a splicing variation in the F domain of nuclear receptor hepatocyte nuclear factor 4alpha1.
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Identification of an endogenous ligand bound to a native orphan nuclear receptorSpecies-specific transcription in mice carrying human chromosome 21Expression of the hepatic specific V1 messenger ribonucleic acid of the human growth hormone receptor gene is regulated by hepatic nuclear factor (HNF)-4alpha2 and HNF-4alpha8Multiple binding modes between HNF4alpha and the LXXLL motifs of PGC-1alpha lead to full activationFactor XII: what does it contribute to our understanding of the physiology and pathophysiology of hemostasis & thrombosisRole of Nuclear Receptors in Central Nervous System Development and Associated DiseasesLigand-dependent activation of the farnesoid X-receptor directs arginine methylation of histone H3 by CARM1Autoregulation and maturity onset diabetes of the young transcription factors control the human PAX4 promoterARP1 interacts with the 5' flanking region of the coagulation factor VII geneA developmental transition in definitive erythropoiesis: erythropoietin expression is sequentially regulated by retinoic acid receptors and HNF4In vivo role of the HNF4alpha AF-1 activation domain revealed by exon swapping.Hepatocyte nuclear factor 4alpha (nuclear receptor 2A1) is essential for maintenance of hepatic gene expression and lipid homeostasisWhat are nuclear receptor ligands?Src tyrosine kinase phosphorylation of nuclear receptor HNF4α correlates with isoform-specific loss of HNF4α in human colon cancer.Inhibitor of the tissue-specific transcription factor HNF4, a potential regulator in early Xenopus development.Combined cis-regulator elements as important mechanism affecting FXII plasma levelsMED25 is a mediator component of HNF4α-driven transcription leading to insulin secretion in pancreatic beta-cells.Proteomic analysis of native hepatocyte nuclear factor-4α (HNF4α) isoforms, phosphorylation status, and interactive cofactors.Mechanism of a transcriptional cross talk between transforming growth factor-beta-regulated Smad3 and Smad4 proteins and orphan nuclear receptor hepatocyte nuclear factor-4Systematic dissection of coding exons at single nucleotide resolution supports an additional role in cell-specific transcriptional regulation.Mammalian mRNA splice-isoform selection is tightly controlled.Cooperative interaction between hepatocyte nuclear factor 4 alpha and GATA transcription factors regulates ATP-binding cassette sterol transporters ABCG5 and ABCG8.Modulation of hepatocyte nuclear factor-4alpha function by the peroxisome-proliferator-activated receptor-gamma co-activator-1alpha in the acute-phase response.Hepatocyte nuclear factor 4alpha contributes to thyroid hormone homeostasis by cooperatively regulating the type 1 iodothyronine deiodinase gene with GATA4 and Kruppel-like transcription factor 9.General molecular biology and architecture of nuclear receptors.Expression and ecdysteroid responsiveness of the nuclear receptors HR3 and E75 in the crustacean Daphnia magna.The multifunctional estrogen receptor-alpha F domain.An F-domain introduced by alternative splicing regulates activity of the zebrafish thyroid hormone receptor alpha.Messenger RNA processing and its role in diabetes.Functional properties of the R154X HNF-4alpha protein generated by a mutation associated with maturity-onset diabetes of the young, type 1.Role of hepatocyte nuclear factor 4α (HNF4α) in cell proliferation and cancer.Mitogen-activated protein kinase-mediated disruption of enhancer-promoter communication inhibits hepatocyte nuclear factor 4alpha expression.Regulation of hepatocyte identity and quiescence.An enhancer element 6 kb upstream of the mouse HNF4alpha1 promoter is activated by glucocorticoids and liver-enriched transcription factors.Regulatory mechanisms controlling human hepatocyte nuclear factor 4alpha gene expression.Competitive cofactor recruitment by orphan receptor hepatocyte nuclear factor 4alpha1: modulation by the F domain.Differential regulation of constitutive androstane receptor expression by hepatocyte nuclear factor4alpha isoforms.Critical role of charged residues in helix 7 of the ligand binding domain in Hepatocyte Nuclear Factor 4alpha dimerisation and transcriptional activity.Underexpressed coactivators PGC1alpha and SRC1 impair hepatocyte nuclear factor 4 alpha function and promote dedifferentiation in human hepatoma cells.Inhibition of hepatocyte nuclear factor 4 transcriptional activity by the nuclear factor kappaB pathway.
P2860
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P2860
Modulation of transcriptional activation and coactivator interaction by a splicing variation in the F domain of nuclear receptor hepatocyte nuclear factor 4alpha1.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年学术文章
@wuu
1999年学术文章
@zh-cn
1999年学术文章
@zh-hans
1999年学术文章
@zh-my
1999年学术文章
@zh-sg
1999年學術文章
@yue
1999年學術文章
@zh
1999年學術文章
@zh-hant
name
Modulation of transcriptional ...... tocyte nuclear factor 4alpha1.
@en
Modulation of transcriptional ...... tocyte nuclear factor 4alpha1.
@nl
type
label
Modulation of transcriptional ...... tocyte nuclear factor 4alpha1.
@en
Modulation of transcriptional ...... tocyte nuclear factor 4alpha1.
@nl
prefLabel
Modulation of transcriptional ...... tocyte nuclear factor 4alpha1.
@en
Modulation of transcriptional ...... tocyte nuclear factor 4alpha1.
@nl
P2093
P2860
P356
P1476
Modulation of transcriptional ...... tocyte nuclear factor 4alpha1.
@en
P2093
F M Sladek
L Nepomuceno
M R Stallcup
P2860
P304
P356
10.1128/MCB.19.10.6509
P407
P577
1999-10-01T00:00:00Z