Posttranslational modification of Bcl-2 facilitates its proteasome-dependent degradation: molecular characterization of the involved signaling pathway.
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Nitric oxide down-regulates MKP-3 mRNA levels: involvement in endothelial cell protection from apoptosisRole of S-nitrosylation in apoptosis resistance and carcinogenesisS-nitrosylation of Bcl-2 inhibits its ubiquitin-proteasomal degradation - a novel antiapoptotic mechanism that suppresses apoptosisSuperoxide-mediated proteasomal degradation of Bcl-2 determines cell susceptibility to Cr(VI)-induced apoptosisMitochondrial superoxide mediates doxorubicin-induced keratinocyte apoptosis through oxidative modification of ERK and Bcl-2 ubiquitinationIBRDC2, an IBR-type E3 ubiquitin ligase, is a regulatory factor for Bax and apoptosis activationRelated F-box proteins control cell death in Caenorhabditis elegans and human lymphomaIEX-1: a new ERK substrate involved in both ERK survival activity and ERK activationThe Bax subfamily of Bcl2-related proteins is essential for apoptotic signal transduction by c-Jun NH(2)-terminal kinaseExtracellular signal-regulated kinases phosphorylate mitogen-activated protein kinase phosphatase 3/DUSP6 at serines 159 and 197, two sites critical for its proteasomal degradationUbiquitin-proteasome system as a modulator of cell fateIdentification of methylated proteins in the yeast small ribosomal subunit: a role for SPOUT methyltransferases in protein arginine methylation.The flexible loop of Bcl-2 is required for molecular interaction with immunosuppressant FK-506 binding protein 38 (FKBP38)Survival-factor-induced phosphorylation of Bad results in its dissociation from Bcl-x(L) but not Bcl-2Nitrosothiol signaling and protein nitrosation in cell deathMDA-7/IL-24 induces Bcl-2 denitrosylation and ubiquitin-degradation involved in cancer cell apoptosisPristimerin Induces Apoptosis in Prostate Cancer Cells by Down-regulating Bcl-2 through ROS-dependent Ubiquitin-proteasomal Degradation PathwayMono- and multisite phosphorylation enhances Bcl2's antiapoptotic function and inhibition of cell cycle entry functionsDual-specific phosphatase-6 (Dusp6) and ERK mediate AMPA receptor-induced oligodendrocyte deathCyanide-induced death of dopaminergic cells is mediated by uncoupling protein-2 up-regulation and reduced Bcl-2 expressionRole of ubiquitin carboxy terminal hydrolase-L1 in neural cell apoptosis induced by ischemic retinal injury in vivoThe Stability and Expression Level of Bok Are Governed by Binding to Inositol 1,4,5-Trisphosphate ReceptorsToward functional proteomics of alveolar macrophages.Role of proteasomes in disease.Conjugated linoleic acid induces apoptosis through estrogen receptor alpha in human breast tissue.Synergistic interactions between interferon-gamma and TRAIL modulate c-FLIP in endothelial cells, mediating their lineage-specific sensitivity to thrombotic thrombocytopenic purpura plasma-associated apoptosisRegulatory role of proteasome in determination of platelet life spanPristimerin, a quinonemethide triterpenoid, induces apoptosis in pancreatic cancer cells through the inhibition of pro-survival Akt/NF-κB/mTOR signaling proteins and anti-apoptotic Bcl-2.Caspase proteolysis of the integrin beta4 subunit disrupts hemidesmosome assembly, promotes apoptosis, and inhibits cell migration.B56 regulatory subunit of protein phosphatase 2A mediates valproic acid-induced p300 degradationUpregulation of cellular Bcl-2 by the KSHV encoded RTA promotes virion productionNerve growth factor inhibits apoptosis in memory B lymphocytes via inactivation of p38 MAPK, prevention of Bcl-2 phosphorylation, and cytochrome c release.The protein kinase C inhibitor enzastaurin exhibits antitumor activity against uveal melanomaDysregulation of apoptotic signaling in cancer: molecular mechanisms and therapeutic opportunitiesc-Jun NH2-terminal kinase-induced proteasomal degradation of c-FLIPL/S and Bcl2 sensitize prostate cancer cells to Fas- and mitochondria-mediated apoptosis by tetrandrineThe natively disordered loop of Bcl-2 undergoes phosphorylation-dependent conformational change and interacts with Pin1Fractalkine promotes human monocyte survival via a reduction in oxidative stressActivation of GluR6-containing kainate receptors induces ubiquitin-dependent Bcl-2 degradation via denitrosylation in the rat hippocampus after kainate treatmentProtein ubiquitination in lymphoid malignancies.Apoptosis induction by Bid requires unconventional ubiquitination and degradation of its N-terminal fragment.
P2860
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P2860
Posttranslational modification of Bcl-2 facilitates its proteasome-dependent degradation: molecular characterization of the involved signaling pathway.
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年学术文章
@wuu
2000年学术文章
@zh-cn
2000年学术文章
@zh-hans
2000年学术文章
@zh-my
2000年学术文章
@zh-sg
2000年學術文章
@yue
2000年學術文章
@zh
2000年學術文章
@zh-hant
name
Posttranslational modification ...... he involved signaling pathway.
@en
Posttranslational modification ...... he involved signaling pathway.
@nl
type
label
Posttranslational modification ...... he involved signaling pathway.
@en
Posttranslational modification ...... he involved signaling pathway.
@nl
prefLabel
Posttranslational modification ...... he involved signaling pathway.
@en
Posttranslational modification ...... he involved signaling pathway.
@nl
P2093
P2860
P1476
Posttranslational modification ...... the involved signaling pathway
@en
P2093
A M Zeiher
K Breitschopf
P2860
P304
P356
10.1128/MCB.20.5.1886-1896.2000
P407
P577
2000-03-01T00:00:00Z