A polymeric nanoparticle encapsulated small-molecule inhibitor of Hedgehog signaling (NanoHHI) bypasses secondary mutational resistance to Smoothened antagonists.
about
Drug Delivery Using Nanoparticles for Cancer Stem-Like Cell TargetingTargeting self-renewal pathways in cancer stem cells: clinical implications for cancer therapyTargeting cancer stem cells by using the nanoparticlesHedgehog signaling pathway and its targets for treatment in basal cell carcinomaCan nanomedicines kill cancer stem cells?Growth Arrest Specific 1 (Gas1) Gene Overexpression in Liver Reduces the In Vivo Progression of Murine Hepatocellular Carcinoma and Partially Restores Gene Expression LevelsAdvanced treatment for basal cell carcinomas.Nanocarrier for poorly water-soluble anticancer drugs--barriers of translation and solutions.Nanomedicine strategies to overcome the pathophysiological barriers of pancreatic cancer.Polymeric nanoparticle-encapsulated hedgehog pathway inhibitor HPI-1 (NanoHHI) inhibits systemic metastases in an orthotopic model of human hepatocellular carcinomaHedgehog signaling pathway and ovarian cancer.Targeting hedgehog signaling in cancer: research and clinical developments.Urokinase plasminogen activator system-targeted delivery of nanobins as a novel ovarian cancer therapy.Nanomaterials in Targeting Cancer Stem Cells for Cancer TherapyAdvanced basal cell carcinoma.Recent advances in the design of Hedgehog pathway inhibitors for the treatment of malignancies.Nanocarrier-mediated drugs targeting cancer stem cells: an emerging delivery approach.Modifying the tumor microenvironment using nanoparticle therapeuticsInvestigational agents in metastatic basal cell carcinoma: focus on vismodegib.HhAntag, a Hedgehog Signaling Antagonist, Suppresses Chondrogenesis and Modulates Canonical and Non-Canonical BMP Signaling.Combined Inhibition of Cyclin-Dependent Kinases (Dinaciclib) and AKT (MK-2206) Blocks Pancreatic Tumor Growth and Metastases in Patient-Derived Xenograft Models.Pancreatic cancer: translational research aspects and clinical implications.S100A4 expression is a prognostic indicator in small intestine adenocarcinoma.The potential of multi-compound nanoparticles to bypass drug resistance in cancer.Glioma-Associated Oncogene Homolog Inhibitors Have the Potential of Suppressing Cancer Stem Cells of Breast Cancer.Hedgehog signalling pathway inhibitors as cancer suppressing agentsRole of GLI Transcription Factors in Pathogenesis and Their Potential as New Therapeutic Targets
P2860
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P2860
A polymeric nanoparticle encapsulated small-molecule inhibitor of Hedgehog signaling (NanoHHI) bypasses secondary mutational resistance to Smoothened antagonists.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年学术文章
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2011年学术文章
@zh-cn
2011年学术文章
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2011年学术文章
@zh-my
2011年学术文章
@zh-sg
2011年學術文章
@yue
2011年學術文章
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2011年學術文章
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name
A polymeric nanoparticle encap ...... nce to Smoothened antagonists.
@en
A polymeric nanoparticle encapsulated small-molecule inhibitor of Hedgehog signaling
@nl
type
label
A polymeric nanoparticle encap ...... nce to Smoothened antagonists.
@en
A polymeric nanoparticle encapsulated small-molecule inhibitor of Hedgehog signaling
@nl
prefLabel
A polymeric nanoparticle encap ...... nce to Smoothened antagonists.
@en
A polymeric nanoparticle encapsulated small-molecule inhibitor of Hedgehog signaling
@nl
P2093
P2860
P50
P1476
A polymeric nanoparticle encap ...... nce to Smoothened antagonists.
@en
P2093
Blake T Aftab
Chaoxin Hu
Collins Karikari
Dipankar Pramanik
Michelle A Rudek
Nathaniel R Campbell
Saeed R Khan
Venugopal Chenna
P2860
P304
P356
10.1158/1535-7163.MCT-11-0341
P577
2011-10-25T00:00:00Z