Dynamin 2 mediates PDGFRα-SHP-2-promoted glioblastoma growth and invasion
about
A novel AHI-1-BCR-ABL-DNM2 complex regulates leukemic properties of primitive CML cells through enhanced cellular endocytosis and ROS-mediated autophagy.Cyclin G2 promotes hypoxia-driven local invasion of glioblastoma by orchestrating cytoskeletal dynamics.Dynamin 2 potentiates invasive migration of pancreatic tumor cells through stabilization of the Rac1 GEF Vav1CUEDC2 suppresses glioma tumorigenicity by inhibiting the activation of STAT3 and NF-κB signaling pathwayMicroRNA-34A inhibits the growth, invasion and metastasis of gastric cancer by targeting PDGFR and MET expressionPDGF receptor-α does not promote HCMV entry into epithelial and endothelial cells but increased quantities stimulate entry by an abnormal pathway.Inhibition of SHP2-mediated dephosphorylation of Ras suppresses oncogenesisPDGF receptor alpha inhibition induces apoptosis in glioblastoma cancer stem cells refractory to anti-Notch and anti-EGFR treatment.MiR-34a/c-Dependent PDGFR-α/β Downregulation Inhibits Tumorigenesis and Enhances TRAIL-Induced Apoptosis in Lung CancerA critical role for PDGFRα signaling in medial nasal process development.Dynamin2 downregulation delays EGFR endocytic trafficking and promotes EGFR signaling and invasion in hepatocellular carcinoma.PCSK9 regulates apoptosis in human neuroglioma u251 cells via mitochondrial signaling pathways.Protein kinase A-dependent phosphorylation of Dock180 at serine residue 1250 is important for glioma growth and invasion stimulated by platelet derived-growth factor receptor α.Increased expression of tyrosine phosphatase SHP-2 in Helicobacter pylori-infected gastric cancerAbnormal PTPN11 enhancer methylation promotes rheumatoid arthritis fibroblast-like synoviocyte aggressiveness and joint inflammationActin bundling by dynamin 2 and cortactin is implicated in cell migration by stabilizing filopodia in human non-small cell lung carcinoma cells.SHP-2-upregulated ZEB1 is important for PDGFRα-driven glioma epithelial-mesenchymal transition and invasion in mice and humans.Tanshinone-1 induces tumor cell killing, enhanced by inhibition of secondary activation of signaling networks.Targeting High Dynamin-2 (DNM2) Expression by Restoring Ikaros Function in Acute Lymphoblastic Leukemia.Overexpression of DCF1 inhibits glioma through destruction of mitochondria and activation of apoptosis pathway.Shp2 Inhibits Proliferation of Esophageal Squamous Cell Cancer via Dephosphorylation of Stat3Spatial regulation of receptor tyrosine kinases in development and cancer.Implications of Rho GTPase Signaling in Glioma Cell Invasion and Tumor Progression.Systematic review of protein biomarkers of invasive behavior in glioblastoma.Distinct functions of dynamin isoforms in tumorigenesis and their potential as therapeutic targets in cancer.miR-638 promotes melanoma metastasis and protects melanoma cells from apoptosis and autophagy.The RNA-binding protein Rbfox2: an essential regulator of EMT-driven alternative splicing and a mediator of cellular invasion.Dynamin inhibitors impair endocytosis and mitogenic signaling of PDGF.Protein tyrosine phosphatase expression profile of rheumatoid arthritis fibroblast-like synoviocytes: a novel role of SH2 domain-containing phosphatase 2 as a modulator of invasion and survival.New approaches to prevent LEOPARD syndrome-associated cardiac hypertrophy by specifically targeting Shp2-dependent signaling.Migration Phenotype of Brain-Cancer Cells Predicts Patient OutcomesCharacterization of dual PTEN and p53-targeting microRNAs identifies microRNA-638/Dnm2 as a two-hit oncogenic locus.TRIM24 is an oncogenic transcriptional co-activator of STAT3 in glioblastoma.Histone Acetyltransferase KAT6A Upregulates PI3K/AKT Signaling through TRIM24 Binding.Dihydroartemisinin selectively inhibits PDGFRα-positive ovarian cancer growth and metastasis through inducing degradation of PDGFRα protein.Hepatic stellate cell-derived PDGFRα-enriched extracellular vesicles promote liver fibrosis in mice through SHP2.
P2860
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P2860
Dynamin 2 mediates PDGFRα-SHP-2-promoted glioblastoma growth and invasion
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Dynamin 2 mediates PDGFRα-SHP-2-promoted glioblastoma growth and invasion
@en
Dynamin 2 mediates PDGFRα-SHP-2-promoted glioblastoma growth and invasion.
@nl
type
label
Dynamin 2 mediates PDGFRα-SHP-2-promoted glioblastoma growth and invasion
@en
Dynamin 2 mediates PDGFRα-SHP-2-promoted glioblastoma growth and invasion.
@nl
prefLabel
Dynamin 2 mediates PDGFRα-SHP-2-promoted glioblastoma growth and invasion
@en
Dynamin 2 mediates PDGFRα-SHP-2-promoted glioblastoma growth and invasion.
@nl
P2093
P2860
P356
P1433
P1476
Dynamin 2 mediates PDGFRα-SHP-2-promoted glioblastoma growth and invasion
@en
P2093
G R Johnson
M A McNiven
P2860
P2888
P304
P356
10.1038/ONC.2011.436
P407
P577
2011-09-26T00:00:00Z