Differential roles for the p101 and p84 regulatory subunits of PI3Kγ in tumor growth and metastasis.
about
Targeting p110gamma in gastrointestinal cancers: attack on multiple frontsMore paths to PI3KγMolecular determinants of PI3Kγ-mediated activation downstream of G-protein-coupled receptors (GPCRs)Caffeine and the analog CGS 15943 inhibit cancer cell growth by targeting the phosphoinositide 3-kinase/Akt pathway.The relationship between mTOR signalling pathway and recombinant antibody productivity in CHO cell lines.Stat1 stimulates cap-independent mRNA translation to inhibit cell proliferation and promote survival in response to antitumor drugsManic fringe promotes a claudin-low breast cancer phenotype through notch-mediated PIK3CG induction.Different inhibition of Gβγ-stimulated class IB phosphoinositide 3-kinase (PI3K) variants by a monoclonal antibody. Specific function of p101 as a Gβγ-dependent regulator of PI3Kγ enzymatic activity.The PI3K/AKT/mTOR pathway is a potential predictor of distinct invasive and migratory capacities in human ovarian cancer cell linesIdentification of upregulated phosphoinositide 3-kinase γ as a target to suppress breast cancer cell migration and invasion.p87 and p101 subunits are distinct regulators determining class IB phosphoinositide 3-kinase (PI3K) specificityRole of phosphoinositide 3-kinase in the pathogenesis of acute pancreatitis.p84 forms a negative regulatory complex with p110γ to control PI3Kγ signalling during cell migration.Gβγ Pathways in Cell Polarity and Migration Linked to Oncogenic GPCR Signaling: Potential Relevance in Tumor Microenvironment.Scaffolding Function of PI3Kgamma Emerges from Enzyme's Shadow.Induction of prolonged early G1 arrest by CDK4/CDK6 inhibition reprograms lymphoma cells for durable PI3Kδ inhibition through PIK3IP1.Comparative proteomic analysis implicates eEF2 as a novel target of PI3Kγ in the MDA-MB-231 metastatic breast cancer cell line.The regulatory subunits of PI3Kγ control distinct neutrophil responses.GPCR Signaling Mediates Tumor Metastasis via PI3KβThe atypical chemokine receptor CCX-CKR regulates metastasis of mammary carcinoma via an effect on EMT.Rac1-stimulated macropinocytosis enhances Gβγ activation of PI3Kβ.Distinct roles for phosphoinositide 3-kinases γ and δ in malignant B cell migration.Up-Regulation of PI 3-Kinases and the Activation of PI3K-Akt Signaling Pathway in Cancer Stem-Like Cells Through DNA Hypomethylation Mediated by the Cancer Microenvironment.
P2860
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P2860
Differential roles for the p101 and p84 regulatory subunits of PI3Kγ in tumor growth and metastasis.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Differential roles for the p10 ...... n tumor growth and metastasis.
@en
Differential roles for the p10 ...... n tumor growth and metastasis.
@nl
type
label
Differential roles for the p10 ...... n tumor growth and metastasis.
@en
Differential roles for the p10 ...... n tumor growth and metastasis.
@nl
prefLabel
Differential roles for the p10 ...... n tumor growth and metastasis.
@en
Differential roles for the p10 ...... n tumor growth and metastasis.
@nl
P2093
P2860
P50
P356
P1433
P1476
Differential roles for the p10 ...... in tumor growth and metastasis
@en
P2093
M D Higgins
M Kochetkova
S Haylock-Jacobs
S R McColl
Y Harata-Lee
P2860
P2888
P304
P356
10.1038/ONC.2011.414
P407
P577
2011-09-26T00:00:00Z