An integrated genomic approach identifies ARID1A as a candidate tumor-suppressor gene in breast cancer.
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The spectrum of SWI/SNF mutations, ubiquitous in human cancersSS18 together with animal-specific factors defines human BAF-type SWI/SNF complexesGenetic and Chromosomal Aberrations and Their Clinical Significance in Renal NeoplasmsEvasion of anti-growth signaling: A key step in tumorigenesis and potential target for treatment and prophylaxis by natural compounds.SWI/SNF chromatin remodeling complexes and cancerARID1A mutations in cancer: another epigenetic tumor suppressor?Promoter hypermethylation of ARID1A gene is responsible for its low mRNA expression in many invasive breast cancersThe SWI/SNF genetic blockade: effects in cell differentiation, cancer and developmental diseasesDeletion of Arid1a in Reproductive Tract Mesenchymal Cells Reduces Fertility in Female Mice.The mutational landscape of chromatin regulatory factors across 4,623 tumor samples.Identifying cancer type specific oncogenes and tumor suppressors using limited size data.CARM1 and BAF155: an example of how chromatin remodeling factors can be relocalized and contribute to cancerRoles of deletion of Arid1a, a tumor suppressor, in mouse ovarian tumorigenesisA pan-cancer genome-wide analysis reveals tumour dependencies by induction of nonsense-mediated decayLoss of ARID1A expression sensitizes cancer cells to PI3K- and AKT-inhibitionThe target therapy of ovarian clear cell carcinoma.Decreased expression of the ARID1A gene is associated with poor prognosis in primary gastric cancer.Next-generation sequencing of endoscopic biopsies identifies ARID1A as a tumor-suppressor gene in Barrett's esophagusARID1A alterations are associated with FGFR3-wild type, poor-prognosis, urothelial bladder tumors.Clinicopathologic and prognostic relevance of ARID1A protein loss in colorectal cancerDecreased expression of ARID1A associates with poor prognosis and promotes metastases of hepatocellular carcinoma.Hepatocyte-Specific Arid1a Deficiency Initiates Mouse Steatohepatitis and Hepatocellular Carcinoma.Whole Exome Sequencing Identifies Frequent Somatic Mutations in Cell-Cell Adhesion Genes in Chinese Patients with Lung Squamous Cell CarcinomaWhole-exome sequencing combined with functional genomics reveals novel candidate driver cancer genes in endometrial cancer.Loss of Tumor Suppressor ARID1A Protein Expression Correlates with Poor Prognosis in Patients with Primary Breast Cancer.Inactivating ARID1A Tumor Suppressor Enhances TERT Transcription and Maintains Telomere Length in Cancer Cells.New perspectives on molecular targeted therapy in ovarian clear cell carcinoma.Loss of ARID1A expression correlates with stages of tumor progression in uterine endometrioid carcinomaARID1A mutations and PI3K/AKT pathway alterations in endometriosis and endometriosis-associated ovarian carcinomas.The Primary Effect on the Proteome of ARID1A-mutated Ovarian Clear Cell Carcinoma is Downregulation of the Mevalonate Pathway at the Post-transcriptional Level.Chromatin remodeling gene AT-rich interactive domain-containing protein 1A suppresses gastric cancer cell proliferation by targeting PIK3CA and PDK1.Recent advances in the ARID family: focusing on roles in human cancer.miR-31 targets ARID1A and enhances the oncogenicity and stemness of head and neck squamous cell carcinoma.Genomic and proteomic characterization of ARID1A chromatin remodeller in ampullary tumors.Chromatin regulators with tumor suppressor properties and their alterations in human cancers.Rhabdoid tumors: an initial clue to the role of chromatin remodeling in cancer.Familial rhabdoid tumour 'avant la lettre'--from pathology review to exome sequencing and back again.The emerging roles of ARID1A in tumor suppression.Beyond Mutations: Additional Mechanisms and Implications of SWI/SNF Complex Inactivation.Driver mutations of cancer epigenomes.
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An integrated genomic approach identifies ARID1A as a candidate tumor-suppressor gene in breast cancer.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年学术文章
@wuu
2011年学术文章
@zh-cn
2011年学术文章
@zh-hans
2011年学术文章
@zh-my
2011年学术文章
@zh-sg
2011年學術文章
@yue
2011年學術文章
@zh
2011年學術文章
@zh-hant
name
An integrated genomic approach ...... pressor gene in breast cancer.
@en
An integrated genomic approach ...... pressor gene in breast cancer.
@nl
type
label
An integrated genomic approach ...... pressor gene in breast cancer.
@en
An integrated genomic approach ...... pressor gene in breast cancer.
@nl
prefLabel
An integrated genomic approach ...... pressor gene in breast cancer.
@en
An integrated genomic approach ...... pressor gene in breast cancer.
@nl
P2093
P2860
P50
P356
P1433
P1476
An integrated genomic approach ...... pressor gene in breast cancer.
@en
P2093
C Ferrario
E Przybytkowski
L Cavallone
O Aleynikova
P2860
P2888
P304
P356
10.1038/ONC.2011.386
P407
P577
2011-09-05T00:00:00Z
P6179
1018346729