HmbR, a hemoglobin-binding outer membrane protein of Neisseria meningitidis, undergoes phase variation
about
Phase and antigenic variation in bacteriaIdentification of Neisseria meningitidis genetic loci involved in the modulation of phase variation frequenciesResistance of neisseria meningitidis to the toxic effects of heme iron and other hydrophobic agents requires expression of ght.Transcriptional profiling of Actinobacillus pleuropneumoniae under iron-restricted conditions.Host iron binding proteins acting as niche indicators for Neisseria meningitidisRegulatory role of the MisR/S two-component system in hemoglobin utilization in Neisseria meningitidisDegradation of heme in gram-negative bacteria: the product of the hemO gene of Neisseriae is a heme oxygenase.The phasevarion: a genetic system controlling coordinated, random switching of expression of multiple genes.Use of heme compounds as iron sources by pathogenic neisseriae requires the product of the hemO geneCharacterization and expression of HmuR, a TonB-dependent hemoglobin receptor of Porphyromonas gingivalisexl, an exchangeable genetic island in Neisseria meningitidis.Mutator clones of Neisseria meningitidis in epidemic serogroup A diseaseDevelopment and evaluation of an improved mouse model of meningococcal colonization.Iron transport systems in Neisseria meningitidisThe Neisseria meningitidis ZnuD zinc receptor contributes to interactions with epithelial cells and supports heme utilization when expressed in Escherichia coli.Investigation into the Antigenic Properties and Contributions to Growth in Blood of the Meningococcal Haemoglobin Receptors, HpuAB and HmbR.Populations adapt to fluctuating selection using derived and ancestral allelic diversity.Influence of the combination and phase variation status of the haemoglobin receptors HmbR and HpuAB on meningococcal virulence.Selection and Counterselection of Hia Expression Reveals a Key Role for Phase-Variable Expression of Hia in Infection Caused by Nontypeable Haemophilus influenzae.In-silico prediction and deep-DNA sequencing validation indicate phase variation in 115 Neisseria meningitidis genes.Role and regulation of heme iron acquisition in gram-negative pathogens.Epidemiological evidence for the role of the hemoglobin receptor, hmbR, in meningococcal virulence.Detection of phase variation in expression of proteins involved in hemoglobin and hemoglobin-haptoglobin binding by nontypeable Haemophilus influenzae.The modA10 phasevarion of nontypeable Haemophilus influenzae R2866 regulates multiple virulence-associated traits.Heme Synthesis and Acquisition in Bacterial Pathogens.Multiple mechanisms of phase variation of PorA in Neisseria meningitidis.Inducible, but not constitutive, resistance of gonococci to hydrophobic agents due to the MtrC-MtrD-MtrE efflux pump requires TonB-ExbB-ExbD proteins.Extracellular heme uptake and the challenges of bacterial cell membranes.An immunogenic, surface-exposed domain of Haemophilus ducreyi outer membrane protein HgbA is involved in hemoglobin binding.Phasevarions of Bacterial Pathogens: Methylomics Sheds New Light on Old Enemies.Epidemiology, hypermutation, within-host evolution and the virulence of Neisseria meningitidis.Genotypic and phenotypic characterization of the O-linked protein glycosylation system reveals high glycan diversity in paired meningococcal carriage isolates.A survey of Type III restriction-modification systems reveals numerous, novel epigenetic regulators controlling phase-variable regulons; phasevarions.Differential expression of hemoglobin receptor, HmbR, between carriage and invasive isolates of Neisseria meningitidis contributes to virulence: lessons from a clonal outbreak.Phasome analysis of pathogenic and commensal Neisseria species expands the known repertoire of phase variable genes, and highlights common adaptive strategies.Interplay Between Virulence and Variability Factors as a Potential Driver of Invasive Meningococcal Disease.
P2860
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P2860
HmbR, a hemoglobin-binding outer membrane protein of Neisseria meningitidis, undergoes phase variation
description
1999 nî lūn-bûn
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1999年の論文
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1999年学术文章
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1999年学术文章
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1999年学术文章
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1999年学术文章
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1999年學術文章
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1999年學術文章
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name
HmbR, a hemoglobin-binding out ...... dis, undergoes phase variation
@en
HmbR, a hemoglobin-binding out ...... is, undergoes phase variation.
@nl
type
label
HmbR, a hemoglobin-binding out ...... dis, undergoes phase variation
@en
HmbR, a hemoglobin-binding out ...... is, undergoes phase variation.
@nl
prefLabel
HmbR, a hemoglobin-binding out ...... dis, undergoes phase variation
@en
HmbR, a hemoglobin-binding out ...... is, undergoes phase variation.
@nl
P2860
P1476
HmbR, a hemoglobin-binding out ...... dis, undergoes phase variation
@en
P2093
A R Richardson
I Stojiljkovic
P2860
P304
P407
P577
1999-04-01T00:00:00Z