Neurotensin signaling activates microRNAs-21 and -155 and Akt, promotes tumor growth in mice, and is increased in human colon tumors - Wikidata - awgldk - TriplyDB

Neurotensin signaling activates microRNAs-21 and -155 and Akt, promotes tumor growth in mice, and is increased in human colon tumors

Neurotensin signaling activates microRNAs-21 and -155 and Akt, promotes tumor growth in mice, and is increased in human colon tumors

http://www.wikidata.org/entity/Q39497062

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Inferring the perturbed microRNA regulatory networks from gene expression data using a network propagation based method.MicroRNA-155 expression is independently predictive of outcome in chordoma.MicroRNA-155 as a proinflammatory regulator via SHIP-1 down-regulation in acute gouty arthritis The role of microRNAs in diabetic nephropathy.MiR-21 simultaneously regulates ERK1 signaling in HSC activation and hepatocyte EMT in hepatic fibrosis Overexpression of miR -155 promotes proliferation and invasion of human laryngeal squamous cell carcinoma via targeting SOCS1 and STAT3.Micro-RNA-155 deficiency prevents alcohol-induced serum endotoxin increase and small bowel inflammation in mice.Modulation by miR-29b of intestinal epithelium homoeostasis through the repression of menin translation.Neurotensin promotes the progression of malignant glioma through NTSR1 and impacts the prognosis of glioma patients.Neurotensin-induced proinflammatory signaling in human colonocytes is regulated by β-arrestins and endothelin-converting enzyme-1-dependent endocytosis and resensitization of neurotensin receptor 1.MicroRNAs: New players in cancer prevention targeting Nrf2, oxidative stress and inflammatory pathways.Neurotensin-induced miR-133α expression regulates neurotensin receptor 1 recycling through its downstream target aftiphilin.MicroRNA-155 deletion promotes tumorigenesis in the azoxymethane-dextran sulfate sodium model of colon cancer.Overexpression of miR-155 promotes the proliferation and invasion of oral squamous carcinoma cells by regulating BCL6/cyclin D2 Decreased miR-199 augments visceral pain in patients with IBS through translational upregulation of TRPV1 Neurotensin receptor 1 overexpression in inflammatory bowel diseases and colitis-associated neoplasia.S100P/RAGE signaling regulates microRNA-155 expression via AP-1 activation in colon cancer NF-κB-driven suppression of FOXO3a contributes to EGFR mutation-independent gefitinib resistance.Inhibition of Smurf2 translation by miR-322/503 modulates TGF-β/Smad2 signaling and intestinal epithelial homeostasis.MicroRNAs in the etiology of colorectal cancer: pathways and clinical implications.MicroRNAs play a central role in molecular dysfunctions linking inflammation with cancer.The pivotal role of microRNA-155 in the control of cancer.Therapeutic microRNAs targeting the NF-kappa B signaling circuits of cancers.Non-coding RNAs in Mammary Gland Development and Disease.Inhibition of neurotensin receptor 1 induces intrinsic apoptosis via let-7a-3p/Bcl-w axis in glioblastoma.Developments in miRNA gene signaling pathways in pancreatic cancer.Neurotensin Promotes the Development of Colitis and Intestinal Angiogenesis via Hif-1α-miR-210 Signaling.A Review of the Role of Neurotensin and Its Receptors in Colorectal Cancer.Epigenetic control of cancer by neuropeptides.Identification of microRNAs regulated by isothiocyanates and association of polymorphisms inside their target sites with risk of sporadic colorectal cancer.Cruciferous vegetables and colorectal cancer prevention through microRNA regulation: A review.Epistasis between microRNAs 155 and 146a during T cell-mediated antitumor immunity.Oncogenic role of neurotensin and neurotensin receptors in various cancers.microRNA-155 silencing inhibits proliferation and migration and induces apoptosis by upregulating BACH1 in renal cancer cells.Neurotensin--regulated miR-133α is involved in proinflammatory signalling in human colonic epithelial cells and in experimental colitis.MicroRNAs as Regulator of Signaling Networks in Metastatic Colon Cancer.MicroRNA-133α regulates neurotensin-associated colonic inflammation in colonic epithelial cells and experimental colitis The neurotensin-HIF-1α-VEGFα axis orchestrates hypoxia, colonic inflammation, and intestinal angiogenesis.Concentration of circulating miRNA-containing particles in serum enhances miRNA detection and reflects CRC tissue-related deregulations.MicroRNA-224 negatively regulates p21 expression during late neoplastic progression in inflammatory bowel disease

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Neurotensin signaling activates microRNAs-21 and -155 and Akt, promotes tumor growth in mice, and is increased in human colon tumors

http://www.wikidata.org/entity/Q39497062

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Neurotensin signaling activate ...... ncreased in human colon tumors

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Neurotensin signaling activate ...... ncreased in human colon tumors

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Neurotensin signaling activate ...... ncreased in human colon tumors

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J.GASTRO.2011.07.038

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Charalabos Pothoulakis

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Christos Polytarchou

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Dimitrios Iliopoulos

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Iordanes Karagiannides

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Kyriaki Bakirtzi

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A microRNA expression signature of human solid tumors defines cancer gene targets

High levels of microRNA-21 in the stroma of colorectal cancers predict short disease-free survival in stage II colon cancer patients

Molecular cloning of the akt oncogene and its human homologues AKT1 and AKT2: amplification of AKT1 in a primary human gastric adenocarcinoma

MicroRNAs: target recognition and regulatory functions

Loss of miR-200 inhibition of Suz12 leads to polycomb-mediated repression required for the formation and maintenance of cancer stem cells

An epigenetic switch involving NF-kappaB, Lin28, Let-7 MicroRNA, and IL6 links inflammation to cell transformation

Curcumin inhibits neurotensin-mediated interleukin-8 production and migration of HCT116 human colon cancer cells

Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets

Identification of novel genes coding for small expressed RNAs

MicroRNA expression profiles classify human cancers

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