Systematic identification of selective essential genes in Helicobacter pylori by genome prioritization and allelic replacement mutagenesis
about
A multi-level multi-scale approach to study essential genes in Mycobacterium tuberculosisA genome-scale analysis for identification of genes required for growth or survival of Haemophilus influenzaeOxidative-stress resistance mutants of Helicobacter pylori.From genetic footprinting to antimicrobial drug targets: examples in cofactor biosynthetic pathwaysPathogen DNA as target for host-generated oxidative stress: role for repair of bacterial DNA damage in Helicobacter pylori colonizationAlternative spermidine biosynthetic route is critical for growth of Campylobacter jejuni and is the dominant polyamine pathway in human gut microbiotaIdentification of Helicobacter pylori genes that contribute to stomach colonizationHelicobacter pylori usurps cell polarity to turn the cell surface into a replicative nicheHelicobacter pylori CheZ(HP) and ChePep form a novel chemotaxis-regulatory complex distinct from the core chemotaxis signaling proteins and the flagellar motor.Enzymes associated with reductive activation and action of nitazoxanide, nitrofurans, and metronidazole in Helicobacter pylori.MrkH, a novel c-di-GMP-dependent transcriptional activator, controls Klebsiella pneumoniae biofilm formation by regulating type 3 fimbriae expressionPoint mutations in Helicobacter pylori's fur regulatory gene that alter resistance to metronidazole, a prodrug activated by chemical reductionCag3 is a novel essential component of the Helicobacter pylori Cag type IV secretion system outer membrane subcomplexHelicobacter pylori AddAB helicase-nuclease and RecA promote recombination-related DNA repair and survival during stomach colonizationFrom knock-out phenotype to three-dimensional structure of a promising antibiotic target from Streptococcus pneumoniaePrediction and identification of sequences coding for orphan enzymes using genomic and metagenomic neighboursOuter membrane biogenesis in Escherichia coli, Neisseria meningitidis, and Helicobacter pylori: paradigm deviations in H. pyloriSynthesis and Antimicrobial Evaluation of Amixicile-Based Inhibitors of the Pyruvate-Ferredoxin Oxidoreductases of Anaerobic Bacteria and Epsilonproteobacteria.Response to metronidazole and oxidative stress is mediated through homeostatic regulator HsrA (HP1043) in Helicobacter pylori.Mutations to essential orphan response regulator HP1043 of Helicobacter pylori result in growth-stage regulatory defects.Helicobacter pylori relies primarily on the purine salvage pathway for purine nucleotide biosynthesisDsbA2 (27 kDa Com1-like protein) of Legionella pneumophila catalyses extracytoplasmic disulphide-bond formation in proteins including the Dot/Icm type IV secretion systemFlavodoxin:quinone reductase (FqrB): a redox partner of pyruvate:ferredoxin oxidoreductase that reversibly couples pyruvate oxidation to NADPH production in Helicobacter pylori and Campylobacter jejuni.Antisense RNA modulation of alkyl hydroperoxide reductase levels in Helicobacter pylori correlates with organic peroxide toxicity but not infectivity.The Helicobacter pylori chemotaxis receptor TlpB (HP0103) is required for pH taxis and for colonization of the gastric mucosaIdentification and characterization of Helicobacter pylori genes essential for gastric colonizationHelicobacter pylori perturbs iron trafficking in the epithelium to grow on the cell surfaceGlobal transposon mutagenesis and essential gene analysis of Helicobacter pylori.Novel therapeutic targets in Helicobacter pylori.Three factors underlying incorrect in silico predictions of essential metabolic genesLarge-scale transposon mutagenesis of Mycoplasma pulmonisRecombination-based in vivo expression technology identifies Helicobacter pylori genes important for host colonizationGenome sequence analysis of Helicobacter pylori strains associated with gastric ulceration and gastric cancer.Contribution of the pst-phoU operon to cell adherence by atypical enteropathogenic Escherichia coli and virulence of Citrobacter rodentiumHelicobacter pylori lipopolysaccharide modification, Lewis antigen expression, and gastric colonization are cholesterol-dependent.Expression of three essential antioxidants of Helicobacter pylori in clinical isolates.Helicobacter pylori gene silencing in vivo demonstrates urease is essential for chronic infection.Transcriptional analysis of the grlRA virulence operon from Citrobacter rodentium.ChePep controls Helicobacter pylori Infection of the gastric glands and chemotaxis in the Epsilonproteobacteria.Host-interactive genes in Amerindian Helicobacter pylori diverge from their Old World homologs and mediate inflammatory responses.
P2860
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P2860
Systematic identification of selective essential genes in Helicobacter pylori by genome prioritization and allelic replacement mutagenesis
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
2001年學術文章
@zh
2001年學術文章
@zh-hant
name
Systematic identification of s ...... llelic replacement mutagenesis
@en
Systematic identification of s ...... lelic replacement mutagenesis.
@nl
type
label
Systematic identification of s ...... llelic replacement mutagenesis
@en
Systematic identification of s ...... lelic replacement mutagenesis.
@nl
prefLabel
Systematic identification of s ...... llelic replacement mutagenesis
@en
Systematic identification of s ...... lelic replacement mutagenesis.
@nl
P2093
P2860
P1476
Systematic identification of s ...... llelic replacement mutagenesis
@en
P2093
A F Chalker
H W Minehart
K K Brinkman
K K Koretke
M A Lonetto
M J Stanhope
N J Hughes
P S Hoffman
P2860
P304
P356
10.1128/JB.183.4.1259-1268.2001
P407
P577
2001-02-01T00:00:00Z