Double-signal hypothesis for thrombin initiation of cell proliferation.

Double-signal hypothesis for thrombin initiation of cell proliferation.

Item
http://www.wikidata.org/entity/Q39505434
The refined 1.9-Å X-ray crystal structure of d-Phe-Pro-Arg chloromethylketone-inhibited human α-thrombin: Structure analysis, overall structure, electrostatic properties, detailed active-site geometry, and structure-function relationshipsDes-gamma-carboxy prothrombin as a useful predisposing factor for the development of portal venous invasion in patients with hepatocellular carcinoma: a prospective analysis of 227 patients.Monoclonal antibody to the thrombin receptor stimulates DNA synthesis in combination with gamma-thrombin or phorbol myristate acetatePAR1-dependent and independent increases in COX-2 and PGE2 in human colonic myofibroblasts stimulated by thrombin.Expression and secretion of gro/MGSA by stimulated human endothelial cells.Cellular consequences of thrombin-receptor activation.Synergistic actions of a thrombin-derived synthetic peptide and a thrombin receptor-activating peptide in stimulating fibroblast mitogenesis.Deendothelialization in vivo initiates a thrombogenic reaction at the rabbit aorta surface. Correlation of uptake of fibrinogen and antithrombin III with thrombin generation by the exposed subendothelium.Thrombin-stimulated growth, clustering, and collagen lattice contraction of human gingival fibroblasts is associated with its protease activity.Inhibition of platelet activation prevents the P-selectin and integrin-dependent accumulation of cancer cell microparticles and reduces tumor growth and metastasis in vivo.Curcumin inhibits thrombin-stimulated connective tissue growth factor (CTGF/CCN2) production through c-Jun NH2-terminal kinase suppression in human gingival fibroblasts.
P2860

Double-signal hypothesis for thrombin initiation of cell proliferation.

Item
http://www.wikidata.org/entity/Q39505434
description
1986 nî lūn-bûn
@nan
1986年の論文
@ja
1986年学术文章
@wuu
1986年学术文章
@zh-cn
1986年学术文章
@zh-hans
1986年学术文章
@zh-my
1986年学术文章
@zh-sg
1986年學術文章
@yue
1986年學術文章
@zh
1986年學術文章
@zh-hant
name
Double-signal hypothesis for thrombin initiation of cell proliferation.
@en
Double-signal hypothesis for thrombin initiation of cell proliferation.
@nl
type
label
Double-signal hypothesis for thrombin initiation of cell proliferation.
@en
Double-signal hypothesis for thrombin initiation of cell proliferation.
@nl
prefLabel
Double-signal hypothesis for thrombin initiation of cell proliferation.
@en
Double-signal hypothesis for thrombin initiation of cell proliferation.
@nl
P1433
P1476
P2093
P304
P31
P356
P433
P478
P577
P698
P356
P1433
P1476
Double-signal hypothesis for thrombin initiation of cell proliferation.
@en
P2093
P304
P31
P356
P433
P478
P577
P698