Short-term correction of arginase deficiency in a neonatal murine model with a helper-dependent adenoviral vector.
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Inducible arginase 1 deficiency in mice leads to hyperargininemia and altered amino acid metabolismStrategies to rescue the consequences of inducible arginase-1 deficiency in miceProof-of-Concept Gene Editing for the Murine Model of Inducible Arginase-1 DeficiencyMyD88-dependent silencing of transgene expression during the innate and adaptive immune response to helper-dependent adenovirus.Development of operational immunologic tolerance with neonatal gene transfer in nonhuman primates: preliminary studies.RH10 provides superior transgene expression in mice when compared with natural AAV serotypes for neonatal gene therapy.Helper-dependent adenoviral vectors for liver-directed gene therapy.Minimal ureagenesis is necessary for survival in the murine model of hyperargininemia treated by AAV-based gene therapy.Helicobacter pylori arginase mutant colonizes arginase II knockout mice.Perinatal gene transfer to the liver.Myocyte-mediated arginase expression controls hyperargininemia but not hyperammonemia in arginase-deficient mice.Long-term survival of the juvenile lethal arginase-deficient mouse with AAV gene therapy.Combinatorial treatment with oncolytic adenovirus and helper-dependent adenovirus augments adenoviral cancer gene therapy.Rescue of the Functional Alterations of Motor Cortical Circuits in Arginase Deficiency by Neonatal Gene Therapy.Lethal phenotype in conditional late-onset arginase 1 deficiency in the mouse.Liver-specific knockout of arginase-1 leads to a profound phenotype similar to inducible whole body arginase-1 deficiency.Innate functions of immunoglobulin M lessen liver gene transfer with helper-dependent adenovirus.Restoring Ureagenesis in Hepatocytes by CRISPR/Cas9-mediated Genomic Addition to Arginase-deficient Induced Pluripotent Stem Cells.Arginase-1 deficiency.
P2860
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P2860
Short-term correction of arginase deficiency in a neonatal murine model with a helper-dependent adenoviral vector.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
2009年论文
@zh
2009年论文
@zh-cn
name
Short-term correction of argin ...... r-dependent adenoviral vector.
@en
Short-term correction of argin ...... r-dependent adenoviral vector.
@nl
type
label
Short-term correction of argin ...... r-dependent adenoviral vector.
@en
Short-term correction of argin ...... r-dependent adenoviral vector.
@nl
prefLabel
Short-term correction of argin ...... r-dependent adenoviral vector.
@en
Short-term correction of argin ...... r-dependent adenoviral vector.
@nl
P2093
P2860
P356
P1433
P1476
Short-term correction of argin ...... er-dependent adenoviral vector
@en
P2093
Adrienne C Dow
Brendan Lee
Chia-Ling Gau
Fides D Lay
Gerald S Lipshutz
Justin Livesay
Robin A Rosenblatt
Stephen D Cederbaum
Wayne W Grody
P2860
P304
P356
10.1038/MT.2009.65
P577
2009-04-14T00:00:00Z