Intracellular delivery of a cytolytic T-lymphocyte epitope peptide by pertussis toxin to major histocompatibility complex class I without involvement of the cytosolic class I antigen processing pathway.
about
The pertussis toxin S1 subunit is a thermally unstable protein susceptible to degradation by the 20S proteasomeRicin A chain insertion into endoplasmic reticulum membranes is triggered by a temperature increase to 37 {degrees}CPertussis toxin plays an early role in respiratory tract colonization by Bordetella pertussisProteolytic cleavage of pertussis toxin S1 subunit is not essential for its activity in mammalian cellsDelivery of multiple epitopes by recombinant detoxified adenylate cyclase of Bordetella pertussis induces protective antiviral immunity.Differential regulation of Bvg-activated virulence factors plays a role in Bordetella pertussis pathogenicityEnhanced delivery of exogenous peptides into the class I antigen processing and presentation pathway.In vivo cytotoxic T lymphocyte elicitation by mycobacterial heat shock protein 70 fusion proteins maps to a discrete domain and is CD4(+) T cell independentAnalysis of BvgA activation of the pertactin gene promoter in Bordetella pertussisOverexpression of the RNA polymerase alpha subunit reduces transcription of Bvg-activated virulence genes in Bordetella pertussis.Evading the proteasome: absence of lysine residues contributes to pertussis toxin activity by evasion of proteasome degradation.
P2860
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P2860
Intracellular delivery of a cytolytic T-lymphocyte epitope peptide by pertussis toxin to major histocompatibility complex class I without involvement of the cytosolic class I antigen processing pathway.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
1999年论文
@zh
1999年论文
@zh-cn
name
Intracellular delivery of a cy ...... I antigen processing pathway.
@en
Intracellular delivery of a cy ...... I antigen processing pathway.
@nl
type
label
Intracellular delivery of a cy ...... I antigen processing pathway.
@en
Intracellular delivery of a cy ...... I antigen processing pathway.
@nl
prefLabel
Intracellular delivery of a cy ...... I antigen processing pathway.
@en
Intracellular delivery of a cy ...... I antigen processing pathway.
@nl
P2093
P2860
P1476
Intracellular delivery of a cy ...... I antigen processing pathway.
@en
P2093
C B O'Connell
G A Hadley
N H Carbonetti
R G Tuskan
U McNamara
P2860
P304
P407
P577
1999-02-01T00:00:00Z