RNAi-mediated silencing of VEGF-C inhibits non-small cell lung cancer progression by simultaneously down-regulating the CXCR4, CCR7, VEGFR-2 and VEGFR-3-dependent axes-induced ERK, p38 and AKT signalling pathways.
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Non-coding RNAs in lung cancerGene Expression Profiles of HIV/AIDS Patients with Qi-Yin Deficiency and Dampness-Heat RetentionRNAi-mediated gene silencing of vascular endothelial growth factor C suppresses growth and induces apoptosis in mouse breast cancer in vitro and in vivo.Novel peptides suppress VEGFR-3 activity and antagonize VEGFR-3-mediated oncogenic effects.Lentivirus vector-mediated knockdown of erythropoietin-producing hepatocellular carcinoma receptors B4 inhibits laser-induced choroidal neovascularization.Novel role for NFAT3 in ERK-mediated regulation of CXCR4Endothelin A receptor antagonism enhances inhibitory effects of anti-ganglioside GD2 monoclonal antibody on invasiveness and viability of human osteosarcoma cells.VEGF-C-VEGFR3/Flt4 axis regulates mammary tumor growth and metastasis in an autocrine manner.A systematic review and meta-analysis of randomized trials on the role of targeted therapy in the management of advanced gastric cancer: Evidence does not translate?Investigational agent MLN9708/2238 targets tumor-suppressor miR33b in MM cells.CCR7 enhances TGF-β1-induced epithelial-mesenchymal transition and is associated with lymph node metastasis and poor overall survival in gastric cancer.The role of the VEGF-C/VEGFRs axis in tumor progression and therapy.CXCR4-targeted therapy inhibits VEGF expression and chondrosarcoma angiogenesis and metastasis.Differential effects of MTSS1 on invasion and proliferation in subtypes of non-small cell lung cancer cellsUse of NRP1, a novel biomarker, along with VEGF-C, VEGFR-3, CCR7 and SEMA3E, to predict lymph node metastasis in squamous cell carcinoma of the tongue.Lentiviral-mediated RNA interference targeting stathmin1 gene in human gastric cancer cells inhibits proliferation in vitro and tumor growth in vivo.Promotion of metastasis of thyroid cancer cells via NRP-2-mediated induction.Therapeutic face of RNAi: in vivo challenges.Annexin A5 promotes invasion and chemoresistance to temozolomide in glioblastoma multiforme cells.Effectiveness of local injection of lentivirus-delivered stathmin1 and stathmin1 shRNA in human gastric cancer xenograft mouse.Overexpression of AKIP1 promotes angiogenesis and lymphangiogenesis in human esophageal squamous cell carcinoma.Effects of autocrine vascular endothelial growth factor (VEGF) in non-small cell lung cancer cell line A549.Lentivirus-mediated RNAi knockdown of NUPR1 inhibits human nonsmall cell lung cancer growth in vitro and in vivo.Protein kinase C epsilon and genetic networks in osteosarcoma metastasis.Expression of vascular endothelial growth factor C in human pterygium.The synergistic effect of esophageal squamous cell carcinoma KYSE150 cells and M2 macrophages on lymphatic endothelial cells.Estrogen induces CXCR4 overexpression and CXCR4/CXL12 pathway activation in lung adenocarcinoma cells in vitro.Triptolide Suppresses Alkali Burn-Induced Corneal Angiogenesis Along with a Downregulation of VEGFA and VEGFC Expression.CXCR4 pharmacogical inhibition reduces bone and soft tissue metastatic burden by affecting tumor growth and tumorigenic potential in prostate cancer preclinical models.
P2860
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P2860
RNAi-mediated silencing of VEGF-C inhibits non-small cell lung cancer progression by simultaneously down-regulating the CXCR4, CCR7, VEGFR-2 and VEGFR-3-dependent axes-induced ERK, p38 and AKT signalling pathways.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
RNAi-mediated silencing of VEG ...... 8 and AKT signalling pathways.
@en
RNAi-mediated silencing of VEG ...... 8 and AKT signalling pathways.
@nl
type
label
RNAi-mediated silencing of VEG ...... 8 and AKT signalling pathways.
@en
RNAi-mediated silencing of VEG ...... 8 and AKT signalling pathways.
@nl
prefLabel
RNAi-mediated silencing of VEG ...... 8 and AKT signalling pathways.
@en
RNAi-mediated silencing of VEG ...... 8 and AKT signalling pathways.
@nl
P2093
P1476
RNAi-mediated silencing of VEG ...... 8 and AKT signalling pathways.
@en
P2093
Jianguo Zhang
Kejian Feng
Shucai Yang
Xiaoli Zhang
Yafang Zhang
Yukuan Feng
P304
P356
10.1016/J.EJCA.2011.05.006
P577
2011-06-15T00:00:00Z