Multiple e-Pharmacophore Modeling Combined with High-Throughput Virtual Screening and Docking to Identify Potential Inhibitors of β-Secretase(BACE1).

Multiple e-Pharmacophore Modeling Combined with High-Throughput Virtual Screening and Docking to Identify Potential Inhibitors of β-Secretase(BACE1).

Item
http://www.wikidata.org/entity/Q39535413
Flavonoids as CDK1 Inhibitors: Insights in Their Binding Orientations and Structure-Activity RelationshipIs It Reliable to Use Common Molecular Docking Methods for Comparing the Binding Affinities of Enantiomer Pairs for Their Protein Target?Virtual Screening, pharmacophore development and structure based similarity search to identify inhibitors against IdeR, a transcription factor of Mycobacterium tuberculosis.Inhibitor design against JNK1 through e-pharmacophore modeling docking and molecular dynamics simulations.E-pharmacophore-based virtual screening to identify GSK-3β inhibitors.Discovery of Novel Mycobacterial DNA Gyrase B Inhibitors: In Silico and In Vitro Biological Evaluation.Chemo- and bioinformatics resources for in silico drug discovery from medicinal plants beyond their traditional use: a critical review.Identification of potential dual agonists of FXR and TGR5 using e-pharmacophore based virtual screening.Population density analysis for determining the protonation state of the catalytic dyad in BACE1-tertiary carbinamine-based inhibitor complex.Quantifying ligand-receptor interactions for gorge-spanning acetylcholinesterase inhibitors for the treatment of Alzheimer's disease.Identification of abelson tyrosine kinase inhibitors as potential therapeutics for Alzheimer's disease using multiple e-pharmacophore modeling and molecular dynamics.In vitro and in silico characterization of angiogenic inhibitors from Sophora interrupta.Exploring molecular fingerprints of selective PPARδ agonists through comparative and validated chemometric techniques.Identification of novel selective MMP-9 inhibitors as potential anti-metastatic lead using structure-based hierarchical virtual screening and molecular dynamics simulation.Investigation of naphthofuran moiety as potential dual inhibitor against BACE-1 and GSK-3β: molecular dynamics simulations, binding energy, and network analysis to identify first-in-class dual inhibitors against Alzheimer's disease.
P2860

Multiple e-Pharmacophore Modeling Combined with High-Throughput Virtual Screening and Docking to Identify Potential Inhibitors of β-Secretase(BACE1).

Item
http://www.wikidata.org/entity/Q39535413
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
Multiple e-Pharmacophore Model ...... tial Inhibitors of β-Secretase
@nl
Multiple e-Pharmacophore Model ...... ibitors of β-Secretase(BACE1).
@en
type
label
Multiple e-Pharmacophore Model ...... tial Inhibitors of β-Secretase
@nl
Multiple e-Pharmacophore Model ...... ibitors of β-Secretase(BACE1).
@en
prefLabel
Multiple e-Pharmacophore Model ...... tial Inhibitors of β-Secretase
@nl
Multiple e-Pharmacophore Model ...... ibitors of β-Secretase(BACE1).
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P433
P478
P577
P698
P356
P1433
P1476
Multiple e-Pharmacophore Model ...... ibitors of β-Secretase(BACE1).
@en
P2093
P2860
P304
P31
P356
P433
P478
P577
P698