Identification of mRNAs that are spliced but not exported to the cytoplasm in the absence of THOC5 in mouse embryo fibroblasts.
about
Aly and THO are required for assembly of the human TREX complex and association of TREX components with the spliced mRNANuclear export of messenger RNATHOC2 Mutations Implicate mRNA-Export Pathway in X-Linked Intellectual DisabilityAn ataxia-telangiectasia-mutated (ATM) kinase mediated response to DNA damage down-regulates the mRNA-binding potential of THOC5The THO complex regulates pluripotency gene mRNA export and controls embryonic stem cell self-renewal and somatic cell reprogrammingTHOC5 controls 3'end-processing of immediate early genes via interaction with polyadenylation specific factor 100 (CPSF100).The Thoc1 encoded ribonucleoprotein is required for myeloid progenitor cell homeostasis in the adult mouseHigh-resolution imaging reveals new features of nuclear export of mRNA through the nuclear pore complexes.THOC5, a member of the mRNA export complex, contributes to processing of a subset of wingless/integrated (Wnt) target mRNAs and integrity of the gut epithelial barrier.Identification of a novel gene signature of ES cells self-renewal fluctuation through system-wide analysis.Splicing-independent loading of TREX on nascent RNA is required for efficient expression of dual-strand piRNA clusters in Drosophila.Human TREX component Thoc5 affects alternative polyadenylation site choice by recruiting mammalian cleavage factor I.THOC5: a novel gene involved in HDL-cholesterol metabolism.THOC5, a member of the mRNA export complex: a novel link between mRNA export machinery and signal transduction pathways in cell proliferation and differentiation.Control of mammalian gene expression by selective mRNA export.Comprehensive analysis of nucleocytoplasmic dynamics of mRNA in Drosophila cells.SR proteins are NXF1 adaptors that link alternative RNA processing to mRNA export.Depletion of three combined THOC5 mRNA export protein target genes synergistically induces human hepatocellular carcinoma cell death.Murine precision-cut liver slices (PCLS): a new tool for studying tumor microenvironments and cell signaling ex vivo.Selective nuclear export of specific classes of mRNA from mammalian nuclei is promoted by GANP.Defects in THO/TREX-2 function cause accumulation of novel cytoplasmic mRNP granules that can be cleared by autophagy.TREX exposes the RNA-binding domain of Nxf1 to enable mRNA export.The THO complex cooperates with the nuclear RNA surveillance machinery to control small nucleolar RNA expression.Transcriptional regulation of immediate-early gene response by THOC5, a member of mRNA export complex, contributes to the M-CSF-induced macrophage differentiation.Myc target gene, long intergenic noncoding RNA, Linc00176 in hepatocellular carcinoma regulates cell cycle and cell survival by titrating tumor suppressor microRNAs.A pathway from leukemogenic oncogenes and stem cell chemokines to RNA processing via THOC5.
P2860
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P2860
Identification of mRNAs that are spliced but not exported to the cytoplasm in the absence of THOC5 in mouse embryo fibroblasts.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Identification of mRNAs that a ...... 5 in mouse embryo fibroblasts.
@en
Identification of mRNAs that a ...... 5 in mouse embryo fibroblasts.
@nl
type
label
Identification of mRNAs that a ...... 5 in mouse embryo fibroblasts.
@en
Identification of mRNAs that a ...... 5 in mouse embryo fibroblasts.
@nl
prefLabel
Identification of mRNAs that a ...... 5 in mouse embryo fibroblasts.
@en
Identification of mRNAs that a ...... 5 in mouse embryo fibroblasts.
@nl
P2093
P2860
P356
P1433
P1476
Identification of mRNAs that a ...... 5 in mouse embryo fibroblasts.
@en
P2093
Alexandra Koch
Anuja Guria
Doan Duy Hai Tran
Hansjörg Hauser
Omar El Bounkari
Priyanka Dutta
Sheetal Ramachandran
Teruko Tamura
P2860
P304
P356
10.1261/RNA.2607011
P407
P577
2011-04-27T00:00:00Z