SV2A in epilepsy: the plot thickens.

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Epilepsy caused by an abnormal alternative splicing with dosage effect of the SV2A gene in a chicken model Synaptic vesicle protein2A decreases in amygdaloid-kindling pharmcoresistant epileptic rats.

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SV2A in epilepsy: the plot thickens.

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http://www.wikidata.org/entity/Q39553786

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2010 nî lūn-bûn

@nan

2010年の論文

@ja

2010年論文

@yue

2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

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2010年论文

@zh

2010年论文

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SV2A in epilepsy: the plot thickens.

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SV2A in epilepsy: the plot thickens.

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SV2A in epilepsy: the plot thickens.

@en

SV2A in epilepsy: the plot thickens.

@nl

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SV2A in epilepsy: the plot thickens.

@en

SV2A in epilepsy: the plot thickens.

@nl

P1476

SV2A in epilepsy: the plot thickens.

@en

P2860

The synaptic vesicle protein SV2A is the binding site for the antiepileptic drug levetiracetam

Abnormal neurotransmission in mice lacking synaptic vesicle protein 2A (SV2A)

SV2A and SV2B function as redundant Ca2+ regulators in neurotransmitter release

Levetiracetam in refractory epilepsy: a prospective observational study.

Experimental and clinical evidence for loss of effect (tolerance) during prolonged treatment with antiepileptic drugs.

Potential new antiepileptogenic targets indicated by microarray analysis in a rat model for temporal lobe epilepsy.

Decreased expression of synaptic vesicle protein 2A, the binding site for levetiracetam, during epileptogenesis and chronic epilepsy.

Proepileptic phenotype of SV2A-deficient mice is associated with reduced anticonvulsant efficacy of levetiracetam.

Development of tolerance to levetiracetam in rats with chronic epilepsy.

SV2A protein is a broad-spectrum anticonvulsant target: functional correlation between protein binding and seizure protection in models of both partial and generalized epilepsy.

P304

47-49

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scholarly article

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10.1111/J.1535-7511.2009.01351.X

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English

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http://www.w3.org/2001/XMLSchema#string

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Graeme J Sills

P577

2010-03-01T00:00:00Z

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P5875

41969547

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20231923

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2836477

http://www.w3.org/2001/XMLSchema#string

SV2A in epilepsy: the plot thickens.

about

P2860

P2860

SV2A in epilepsy: the plot thickens.

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type

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P1433

P1476

P2860

P304

P31

P356

P407

P433

P478

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P577

P5875

P698

P932

P356

P1433

P1476

P2860

P304

P31

P356

P407

P433

P478

P50

P577

P5875

P698

P932