A tetrazolato-bridged dinuclear platinum(II) complex exhibits markedly high in vivo antitumor activity against pancreatic cancer.
about
Chromatin folding and DNA replication inhibition mediated by a highly antitumor-active tetrazolato-bridged dinuclear platinum(II) complexUnique platinum-DNA interactions may lead to more effective platinum-based antitumor drugs.Fast and slow versus strong and weak metal-DNA binding: consequences for anti-cancer activity.Platinum-based drugs: past, present and future.Highly efficient uptake into cisplatin-resistant cells and the isomerization upon coordinative DNA binding of anticancer tetrazolato-bridged dinuclear platinum(II) complexes.Synthesis of antitumor azolato-bridged dinuclear platinum(ii) complexes with in vivo antitumor efficacy and unique in vitro cytotoxicity profiles.An in vivo highly antitumor-active tetrazolato-bridged dinuclear platinum(II) complex largely circumvents in vitro cisplatin resistance: two linkage isomers yield the same product upon reaction with 9-ethylguanine but exhibit different cytotoxic proEffect of the Metal Ion on the Enantioselectivity and Linkage Isomerization of Thiosemicarbazone Helicates.Synthesis, reactivity and characterization of Pt(ii) complexes with N,N' chelating ligands; structure and dimethylsulfoxide reactivity relationship.
P2860
Q36814826-B1E10A47-3139-4839-A7F3-EBB6EE753C74Q37868960-8997B716-DF04-483C-9C14-203D2445EFD0Q38001300-78CD92AC-3DBB-406C-BA12-9F33A81A5E00Q38737115-3883FDB6-C186-4EC0-8D4B-2E05AC2B5224Q38833550-E48BEAFB-244F-4D4D-AD31-1335A1488334Q39162262-A662FC74-98DC-4405-BA56-F569E07E21AFQ39369883-69266A4A-F8A2-4B53-8B22-9333653CA765Q48229023-5D9BF995-B885-4A72-8617-7E0B541122D8Q48365682-7438EF38-0E44-4AF5-BA7E-92506C0ED358
P2860
A tetrazolato-bridged dinuclear platinum(II) complex exhibits markedly high in vivo antitumor activity against pancreatic cancer.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
A tetrazolato-bridged dinuclear platinum
@nl
A tetrazolato-bridged dinuclea ...... ity against pancreatic cancer.
@en
type
label
A tetrazolato-bridged dinuclear platinum
@nl
A tetrazolato-bridged dinuclea ...... ity against pancreatic cancer.
@en
prefLabel
A tetrazolato-bridged dinuclear platinum
@nl
A tetrazolato-bridged dinuclea ...... ity against pancreatic cancer.
@en
P2860
P356
P1433
P1476
A tetrazolato-bridged dinuclea ...... vity against pancreatic cancer
@en
P2093
Masahiko Chikuma
Yuh-Ling Lin
P2860
P304
P356
10.1002/CMDC.201100141
P50
P577
2011-04-15T00:00:00Z