Total synthesis and biological evaluation of (-)-englerin A and B: synthesis of analogues with improved activity profile.
about
Transient receptor potential canonical 4 and 5 proteins as targets in cancer therapeuticsEnglerin a selectively induces necrosis in human renal cancer cellsSynthesis of medicinally relevant terpenes: reducing the cost and time of drug discovery.Concise syntheses of strychnine and englerin A: the power of reductive cyclizations triggered by samarium iodide.Formal synthesis of (-)-englerin A and cytotoxicity studies of truncated englerinsSynthesis of a stable and orally bioavailable englerin analogue.Synthesis and Biological Evaluation of New (-)-Englerin AnaloguesChemical synthesis of the englerins.Strategic innovation in the total synthesis of complex natural products using gold catalysis.(-)-Englerin A-evoked Cytotoxicity Is Mediated by Na+ Influx and Counteracted by Na+/K+-ATPase.Asymmetric Total Synthesis of (-)-Englerin A through Catalytic Diastereo- and Enantioselective Carbonyl Ylide Cycloaddition.(-)-Englerin A is a potent and selective activator of TRPC4 and TRPC5 calcium channels.Unveiling (-)-Englerin A as a Modulator of L-Type Calcium Channels.Collective total synthesis of englerin A and B, orientalol E and F, and oxyphyllol: application of the organocatalytic [4+3] cycloaddition reaction.HPLC-ELSD Quantification and Centrifugal Partition Chromatography Isolation of 8-O-Acetylharpagide from Oxera coronata (Lamiaceae).Mechanistic Characterisation of Two Sesquiterpene Cyclases from the Plant Pathogenic Fungus Fusarium fujikuroi.Assembly of Terpenoid Cores by a Simple, Tunable Strategy.Concise, Enantioselective, and Versatile Synthesis of (-)-Englerin A Based on a Platinum-Catalyzed [4C+3C] Cycloaddition of Allenedienes.Synthesis and biological analysis of truncated calyculone H.Importance of a 4-Alkyl Substituent for Activity in the Englerin Series.
P2860
Q28073760-11E8B29D-A96E-4572-8CBA-EB4330FF02E4Q28484574-5C0675AE-8997-4F8C-976C-6C7BBFA390F0Q34171634-38CA9AB0-1CBB-4338-9C3A-176211FE76CCQ34202744-106F968C-800D-4AAD-87D9-2809D2756934Q35918564-B5A13CCD-6F2C-48C7-9614-23840376B553Q36887630-F9CF44D0-DBE2-4352-B09C-0E2070C3BA4BQ37050231-45B75CD5-B3AB-4506-846E-8DC1B207E197Q37967644-41E67A9F-584B-4B18-953A-D1111484E3E2Q38183271-F01610AA-2436-45EF-8C13-FFB22491D416Q38729643-5E322A76-B387-4333-881A-535DA8456E24Q38852439-6089E708-6329-442F-B0F3-D1251422EE97Q38906824-8037657D-2C69-4328-8767-4F47F42B7583Q41226155-F50A6CA3-4F23-4806-815F-8CEB93794B1AQ43465030-7840E44A-EF50-49E8-886B-FA3187D10259Q46439487-CC0BBDFF-0B6F-4623-ADFE-F0DF26EDB8C1Q48202673-D3796291-9C80-441B-BEB1-7CE4684BCA02Q48217297-E69A1296-669B-4ECC-AF84-8AA80E77DE16Q48248481-B117F108-DD72-47F9-B422-90298114A827Q48651790-D3C5CA2C-B279-4F5C-A5F5-153C926A3D58Q55609506-20262045-D8C4-4E75-A2E7-BF989F9BDBA7
P2860
Total synthesis and biological evaluation of (-)-englerin A and B: synthesis of analogues with improved activity profile.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Total synthesis and biological ...... ith improved activity profile.
@en
type
label
Total synthesis and biological ...... ith improved activity profile.
@en
prefLabel
Total synthesis and biological ...... ith improved activity profile.
@en
P2093
P2860
P50
P356
P1476
Total synthesis and biological ...... ith improved activity profile.
@en
P2093
Lea Radtke
Matthieu Willot
Peter Habenberger
Roland Fröhlich
Slava Ziegler
Stephanie Sauerland
P2860
P304
P356
10.1002/ANIE.201007790
P407
P577
2011-03-29T00:00:00Z