Isoniazid-induced transient high-level resistance in Mycobacterium tuberculosis.
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A balancing act: efflux/influx in mycobacterial drug resistanceContribution of efflux to the emergence of isoniazid and multidrug resistance in Mycobacterium tuberculosisMycobacterium tuberculosis Is Resistant to Isoniazid at a Slow Growth Rate by Single Nucleotide Polymorphisms in katG Codon Ser315Reduced emergence of isoniazid resistance with concurrent use of thioridazine against acute murine tuberculosis.Drug tolerance in replicating mycobacteria mediated by a macrophage-induced efflux mechanism.Tetrandrine reverses drug resistance in isoniazid and ethambutol dual drug-resistant Mycobacterium tuberculosis clinical isolates.Adaptive resistance in bacteria requires epigenetic inheritance, genetic noise, and cost of efflux pumpsAntimicrobial susceptibility testing, drug resistance mechanisms, and therapy of infections with nontuberculous mycobacteria.Role of mycobacterial efflux transporters in drug resistance: an unresolved question.Enhanced killing of intracellular multidrug-resistant Mycobacterium tuberculosis by compounds that affect the activity of efflux pumps.Mechanisms of resistance in bacteria: an evolutionary approachAcceleration of tuberculosis treatment by adjunctive therapy with verapamil as an efflux inhibitorAntimicrobial efflux pumps and Mycobacterium tuberculosis drug tolerance: evolutionary considerations.A simple in vitro PK/PD model system to determine time-kill curves of drugs against Mycobacteria.Molecular tools for rapid identification and novel effective therapy against MDRTB/XDRTB infections.Inhibitors of mycobacterial efflux pumps as potential boosters for anti-tubercular drugs.Why and How the Old Neuroleptic Thioridazine Cures the XDR-TB Patient.Efflux pump inhibitors: targeting mycobacterial efflux systems to enhance TB therapy.Efflux drug transporters at the forefront of antimicrobial resistance.Role of Phenothiazines and Structurally Similar Compounds of Plant Origin in the Fight against Infections by Drug Resistant Bacteria.Thioridazine: A Non-Antibiotic Drug Highly Effective, in Combination with First Line Anti-Tuberculosis Drugs, against Any Form of Antibiotic Resistance of Mycobacterium tuberculosis Due to Its Multi-Mechanisms of Action.Why and how thioridazine in combination with antibiotics to which the infective strain is resistant will cure totally drug-resistant tuberculosis.Efflux-mediated response of Staphylococcus aureus exposed to ethidium bromide.Clinical concentrations of thioridazine kill intracellular multidrug-resistant Mycobacterium tuberculosis.Inducement and reversal of tetracycline resistance in Escherichia coli K-12 and expression of proton gradient-dependent multidrug efflux pump genes.Performance of the GenoType MTBDRplus assay directly on sputum specimens from Brazilian patients with tuberculosis treatment failure or relapse.Antimycobacterial activity of five efflux pump inhibitors against Mycobacterium tuberculosis clinical isolates.Identification of mutations related to streptomycin resistance in clinical isolates of Mycobacterium tuberculosis and possible involvement of efflux mechanism.Isoniazid induces its own resistance in nonreplicating Mycobacterium tuberculosis.Isoniazid bactericidal activity and resistance emergence: integrating pharmacodynamics and pharmacogenomics to predict efficacy in different ethnic populations.Time-kill kinetics of anti-tuberculosis drugs, and emergence of resistance, in relation to metabolic activity of Mycobacterium tuberculosis.Concentration-dependent Mycobacterium tuberculosis killing and prevention of resistance by rifampin.Challenging the Drug-Likeness Dogma for New Drug Discovery in TuberculosisEfflux Pumps in Mycobacteria: Antimicrobial Resistance, Physiological Functions, and Role in Pathogenicity
P2860
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P2860
Isoniazid-induced transient high-level resistance in Mycobacterium tuberculosis.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
2002年论文
@zh
2002年论文
@zh-cn
name
Isoniazid-induced transient high-level resistance in Mycobacterium tuberculosis.
@en
Isoniazid-induced transient high-level resistance in Mycobacterium tuberculosis.
@nl
type
label
Isoniazid-induced transient high-level resistance in Mycobacterium tuberculosis.
@en
Isoniazid-induced transient high-level resistance in Mycobacterium tuberculosis.
@nl
prefLabel
Isoniazid-induced transient high-level resistance in Mycobacterium tuberculosis.
@en
Isoniazid-induced transient high-level resistance in Mycobacterium tuberculosis.
@nl
P2093
P2860
P50
P1476
Isoniazid-induced transient high-level resistance in Mycobacterium tuberculosis.
@en
P2093
Annemarie M Jordaan
Rosário Bettencourt
Thomas C Victor
P2860
P304
P356
10.1128/AAC.46.9.2804-2810.2002
P407
P577
2002-09-01T00:00:00Z