Novel quinazoline HMJ-30 induces U-2 OS human osteogenic sarcoma cell apoptosis through induction of oxidative stress and up-regulation of ATM/p53 signaling pathway.
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Alterations in cellular energy metabolism associated with the antiproliferative effects of the ATM inhibitor KU-55933 and with metforminYC-1 induces G0/G1 phase arrest and mitochondria-dependent apoptosis in cisplatin-resistant human oral cancer CAR cellsAggravated DNA damage as a basis for enhanced glioma cell killing by MJ-66 in combination with minocycline.The crude extract of Corni Fructus induces apoptotic cell death through reactive oxygen species-modulated pathways in U-2 OS human osteosarcoma cells.Activations of Both Extrinsic and Intrinsic Pathways in HCT 116 Human Colorectal Cancer Cells Contribute to Apoptosis through p53-Mediated ATM/Fas Signaling by Emilia sonchifolia Extract, a Folklore Medicinal Plant.Fisetin-induced apoptosis of human oral cancer SCC-4 cells through reactive oxygen species production, endoplasmic reticulum stress, caspase-, and mitochondria-dependent signaling pathways.Crude extract of Rheum palmatum L. Induces cell cycle arrest S phase and apoptosis through mitochondrial-dependent pathways in U-2 OS human osteosarcoma cells.Design, synthesis and in vitro antiproliferative activity of novel isatin-quinazoline hybrids.Ethanol extract of Hedyotis diffusa willd upregulates G0/G1 phase arrest and induces apoptosis in human leukemia cells by modulating caspase cascade signaling and altering associated genes expression was assayed by cDNA microarray.The crude extract of Corni Fructus inhibits the migration and invasion of U-2 OS human osteosarcoma cells through the inhibition of matrix metalloproteinase-2/-9 by MAPK signaling.Endoplasmic reticulum stress contributes to arsenic trioxide-induced intrinsic apoptosis in human umbilical and bone marrow mesenchymal stem cells.Disruption of IGF‑1R signaling by a novel quinazoline derivative, HMJ‑30, inhibits invasiveness and reverses epithelial-mesenchymal transition in osteosarcoma U‑2 OS cells.
P2860
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P2860
Novel quinazoline HMJ-30 induces U-2 OS human osteogenic sarcoma cell apoptosis through induction of oxidative stress and up-regulation of ATM/p53 signaling pathway.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Novel quinazoline HMJ-30 induc ...... of ATM/p53 signaling pathway.
@en
Novel quinazoline HMJ-30 induc ...... of ATM/p53 signaling pathway.
@nl
type
label
Novel quinazoline HMJ-30 induc ...... of ATM/p53 signaling pathway.
@en
Novel quinazoline HMJ-30 induc ...... of ATM/p53 signaling pathway.
@nl
prefLabel
Novel quinazoline HMJ-30 induc ...... of ATM/p53 signaling pathway.
@en
Novel quinazoline HMJ-30 induc ...... of ATM/p53 signaling pathway.
@nl
P2093
P2860
P50
P356
P1476
Novel quinazoline HMJ-30 induc ...... of ATM/p53 signaling pathway.
@en
P2093
Hui-Jye Chen
Mann-Jen Hour
Sheng-Chu Kuo
Wen-Wen Huang
Yu-Jen Chiu
P2860
P304
P356
10.1002/JOR.21398
P577
2011-03-21T00:00:00Z