The Notch ligand Jagged2 promotes lung adenocarcinoma metastasis through a miR-200-dependent pathway in mice
about
Targeting Notch to overcome radiation resistanceRoles of NOTCH1 as a Therapeutic Target and a Biomarker for Lung Cancer: Controversies and PerspectivesMicroRNA regulation of tumorigenesis, cancer progression and interpatient heterogeneity: towards clinical useNon-coding RNAs in lung cancerMiR-200, a new star miRNA in human cancerFrom fly wings to targeted cancer therapies: a centennial for notch signalingThe miR-200 and miR-221/222 microRNA families: opposing effects on epithelial identitySmoking, p53 mutation, and lung cancerNoncoding RNAs in Tumor Epithelial-to-Mesenchymal TransitionmicroRNA-200b as a Switch for Inducible Adult AngiogenesisSignificance of PELP1/HDAC2/miR-200 regulatory network in EMT and metastasis of breast cancerThe miR-200 family and the miR-183~96~182 cluster target Foxf2 to inhibit invasion and metastasis in lung cancers.Common Oncogene Mutations and Novel SND1-BRAF Transcript Fusion in Lung Adenocarcinoma from Never SmokersEpithelial-to-mesenchymal transition drives a pro-metastatic Golgi compaction process through scaffolding protein PAQR11.ZEB1 sensitizes lung adenocarcinoma to metastasis suppression by PI3K antagonism.Expression of Notch Gene and Its Impact on Survival of Patients with Resectable Non-small Cell Lung Cancer.Histone deacetylases, microRNA and leptin crosstalk in pancreatic cancer.Members of the microRNA-200 family are promising therapeutic targets in cancer.Combinatorial interventions inhibit TGFβ-driven epithelial-to-mesenchymal transition and support hybrid cellular phenotypes.The RNA-binding protein DDX1 promotes primary microRNA maturation and inhibits ovarian tumor progression.Downregulation of endothelial microRNA-200b supports cutaneous wound angiogenesis by desilencing GATA binding protein 2 and vascular endothelial growth factor receptor 2A microRNA network regulates expression and biosynthesis of wild-type and DeltaF508 mutant cystic fibrosis transmembrane conductance regulator.The cell of origin and subtype of K-Ras-induced lung tumors are modified by Notch and Sox2.Metastasis is regulated via microRNA-200/ZEB1 axis control of tumour cell PD-L1 expression and intratumoral immunosuppression.Notch3 and HEY-1 as prognostic biomarkers in pancreatic adenocarcinoma.Alveolar type II cells possess the capability of initiating lung tumor developmentNotch signaling and EMT in non-small cell lung cancer: biological significance and therapeutic application.Signaling mechanisms of the epithelial-mesenchymal transition.Pro-Inflammatory Cytokine IL-1β Up-Regulates CXC Chemokine Receptor 4 via Notch and ERK Signaling Pathways in Tongue Squamous Cell Carcinoma.BMP4 depletion by miR-200 inhibits tumorigenesis and metastasis of lung adenocarcinoma cells.MicroRNAs as potential targets for progressive pulmonary fibrosisThe sialyl-glycolipid stage-specific embryonic antigen 4 marks a subpopulation of chemotherapy-resistant breast cancer cells with mesenchymal features.The microRNA-200/Zeb1 axis regulates ECM-dependent β1-integrin/FAK signaling, cancer cell invasion and metastasis through CRKLCXCR2 expression in tumor cells is a poor prognostic factor and promotes invasion and metastasis in lung adenocarcinoma.Notch increases the shedding of HB-EGF by ADAM12 to potentiate invadopodia formation in hypoxia.Control of alveolar differentiation by the lineage transcription factors GATA6 and HOPX inhibits lung adenocarcinoma metastasisThe role of epithelial-mesenchymal transition programming in invasion and metastasis: a clinical perspective.Integrative genetic, epigenetic and pathological analysis of paraganglioma reveals complex dysregulation of NOTCH signaling.Hsa-miR-329 exerts tumor suppressor function through down-regulation of MET in non-small cell lung cancer.High expression of Notch ligand Jagged2 is associated with the metastasis and recurrence in urothelial carcinoma of bladder.
P2860
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P2860
The Notch ligand Jagged2 promotes lung adenocarcinoma metastasis through a miR-200-dependent pathway in mice
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
The Notch ligand Jagged2 promo ...... -200-dependent pathway in mice
@en
The Notch ligand Jagged2 promo ...... 200-dependent pathway in mice.
@nl
type
label
The Notch ligand Jagged2 promo ...... -200-dependent pathway in mice
@en
The Notch ligand Jagged2 promo ...... 200-dependent pathway in mice.
@nl
prefLabel
The Notch ligand Jagged2 promo ...... -200-dependent pathway in mice
@en
The Notch ligand Jagged2 promo ...... 200-dependent pathway in mice.
@nl
P2093
P2860
P50
P356
P1476
The Notch ligand Jagged2 promo ...... -200-dependent pathway in mice
@en
P2093
Chad J Creighton
Cristina A Alvarez
Don L Gibbons
Jonathan M Kurie
Nishan Thilaganathan
Yanan Yang
Young-Ho Ahn
P2860
P304
P356
10.1172/JCI42579
P407
P577
2011-03-14T00:00:00Z