Hematopoietic stem cell-engrafted NOD/SCID/IL2Rgamma null mice develop human lymphoid systems and induce long-lasting HIV-1 infection with specific humoral immune responses. - Wikidata - awgldk - TriplyDB

Hematopoietic stem cell-engrafted NOD/SCID/IL2Rgamma null mice develop human lymphoid systems and induce long-lasting HIV-1 infection with specific humoral immune responses.

Hematopoietic stem cell-engrafted NOD/SCID/IL2Rgamma null mice develop human lymphoid systems and induce long-lasting HIV-1 infection with specific humoral immune responses.

http://www.wikidata.org/entity/Q39580500

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Dengue virus infection and virus-specific HLA-A2 restricted immune responses in humanized NOD-scid IL2rgammanull mice Humanized mice show clinical signs of dengue fever according to infecting virus genotype Multiple APOBEC3 restriction factors for HIV-1 and one Vif to rule them all Studies of retroviral infection in humanized mice Pre-clinical modeling of CCR5 knockout in human hematopoietic stem cells by zinc finger nucleases using humanized mice New generation humanized mice for virus research: comparative aspects and future prospects Mouse models for the study of HCV infection and virus–host interactions Further improvements of the P. falciparum humanized mouse model A topical microbicide gel formulation of CCR5 antagonist maraviroc prevents HIV-1 vaginal transmission in humanized RAG-hu mice Humanized mice recapitulate key features of HIV-1 infection: a novel concept using long-acting anti-retroviral drugs for treating HIV-1 Humanized NOD/SCID/IL2Rgamma(null) mice transplanted with hematopoietic stem cells under nonmyeloablative conditions show prolonged life spans and allow detailed analysis of human immunodeficiency virus type 1 pathogenesis Establishment of HIV-1 resistance in CD4+ T cells by genome editing using zinc-finger nucleases Animal models for HIV/AIDS research HIV-1 Vaccine Trials: Evolving Concepts and Designs Chimeric SCID-hu Model as a Human Hematopoietic Stem Cell Host That Recapitulates the Effects of HIV-1 on Bone Marrow Progenitors in Infected Patients.Dengue virus tropism in humanized mice recapitulates human dengue fever.Mosquito bite delivery of dengue virus enhances immunogenicity and pathogenesis in humanized mice.Current advances in humanized mouse models.Evolution of the HIV-1 env gene in the Rag2-/- gammaC-/- humanized mouse model Oral pre-exposure prophylaxis by anti-retrovirals raltegravir and maraviroc protects against HIV-1 vaginal transmission in a humanized mouse model.Humanized Rag1-/- γc-/- mice support multilineage hematopoiesis and are susceptible to HIV-1 infection via systemic and vaginal routes Inhibition of in vivo HIV infection in humanized mice by gene therapy of human hematopoietic stem cells with a lentiviral vector encoding a broadly neutralizing anti-HIV antibody.Novel mouse xenograft models reveal a critical role of CD4+ T cells in the proliferation of EBV-infected T and NK cells.Epstein-Barr virus induces erosive arthritis in humanized mice.Highly active antiretroviral therapy potently suppresses HIV infection in humanized Rag2-/-gammac-/- mice Human hematopoietic stem/progenitor cells modified by zinc-finger nucleases targeted to CCR5 control HIV-1 in vivo.Animal models for viral infection and cell exhaustion.An improved protocol for efficient engraftment in NOD/LTSZ-SCIDIL-2Rγnull mice allows HIV replication and development of anti-HIV immune responses Links between progressive HIV-1 infection of humanized mice and viral neuropathogenesis Effective elicitation of human effector CD8+ T Cells in HLA-B*51:01 transgenic humanized mice after infection with HIV-1.CD8+ cell depletion accelerates HIV-1 immunopathology in humanized mice.Current humanized mouse models for studying human immunology and HIV-1 immuno-pathogenesis.Dysregulation of claudin-5 in HIV-induced interstitial pneumonitis and lung vascular injury. Protective role of peroxisome proliferator-activated receptor-γ.Creation of "humanized" mice to study human immunity Assessment of benzene-induced hematotoxicity using a human-like hematopoietic lineage in NOD/Shi-scid/IL-2Rγnull mice Humanized mouse models of epstein-barr virus infection and associated diseases.Mouse models with human immunity and their application in biomedical research.Mice with human immune system components as in vivo models for infections with human pathogens.Mucosal transmission of R5 and X4 tropic HIV-1 via vaginal and rectal routes in humanized Rag2-/- gammac -/- (RAG-hu) mice.HIV-1 Vpr accelerates viral replication during acute infection by exploitation of proliferating CD4+ T cells in vivo

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Hematopoietic stem cell-engrafted NOD/SCID/IL2Rgamma null mice develop human lymphoid systems and induce long-lasting HIV-1 infection with specific humoral immune responses.

http://www.wikidata.org/entity/Q39580500

description

2006 nî lūn-bûn

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2006年の論文

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2006年論文

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2006年論文

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Hematopoietic stem cell-engraf ...... ific humoral immune responses.

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Hematopoietic stem cell-engraf ...... ific humoral immune responses.

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type

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Hematopoietic stem cell-engraf ...... ific humoral immune responses.

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Hematopoietic stem cell-engraf ...... ific humoral immune responses.

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Hematopoietic stem cell-engraf ...... ific humoral immune responses.

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Hematopoietic stem cell-engraf ...... ific humoral immune responses.

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Hematopoietic stem cell-engraf ...... ific humoral immune responses.

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Kazuo Terashima

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M Zahidunnabi Dewan

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Mamoru Ito

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Misako Yajima

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Mitsuo Honda

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Norio Shimizu

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Satoru Watanabe

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Shigeo Horibata

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Shinrai Ohta

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Tomohiro Morio

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212-218

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scholarly article

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10.1182/BLOOD-2006-04-017681

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