Cucurbitacin IIa: a novel class of anti-cancer drug inducing non-reversible actin aggregation and inhibiting survivin independent of JAK2/STAT3 phosphorylation.
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Identification of New Shikonin Derivatives as Antitumor Agents Targeting STAT3 SH2 Domain.Cucurbitacin E Induces G(2)/M Phase Arrest through STAT3/p53/p21 Signaling and Provokes Apoptosis via Fas/CD95 and Mitochondria-Dependent Pathways in Human Bladder Cancer T24 Cells.Impact of the biophysical features of a 3D gelatin microenvironment on glioblastoma malignancy.Natural compounds as potential treatments of NF2-deficient schwannoma and meningioma: cucurbitacin D and goyazensolideCucurbitacin IIb exhibits anti-inflammatory activity through modulating multiple cellular behaviors of mouse lymphocytes.VASP activation via the Gα13/RhoA/PKA pathway mediates cucurbitacin-B-induced actin aggregation and cofilin-actin rod formationCucurbitacin E Induces Autophagy via Downregulating mTORC1 Signaling and Upregulating AMPK Activity.Effects of cucurbitacins on cell morphology are associated with sensitization of renal carcinoma cells to TRAIL-induced apoptosis.Simultaneous determination of cucurbitacin IIa and cucurbitacin IIb of Hemsleya amabilis by HPLC-MS/MS and their pharmacokinetic study in normal and indomethacin-induced rats.A natural product-like JAK2/STAT3 inhibitor induces apoptosis of malignant melanoma cells.Cucurbitacin I inhibits Rac1 activation in breast cancer cells by a reactive oxygen species-mediated mechanism and independently of Janus tyrosine kinase 2 and P-Rex1.Terpenoids: natural products for cancer therapy.Cucurbitacins: A Systematic Review of the Phytochemistry and Anticancer Activity.Formation of cofilin-actin rods following cucurbitacin-B-induced actin aggregation depends on Slingshot homolog 1-mediated cofilin hyperactivation.Anti-proliferative effect of 23,24-dihydrocucurbitacin F on human prostate cancer cells through induction of actin aggregation and cofilin-actin rod formation.Enterolobium contortisiliquum trypsin inhibitor (EcTI), a plant proteinase inhibitor, decreases in vitro cell adhesion and invasion by inhibition of Src protein-focal adhesion kinase (FAK) signaling pathways.Cucurbitacin E suppresses cytokine expression in human Jurkat T cells through down-regulating the NF-κB signaling.HPTLC Analysis of Bioactivity Guided Anticancer Enriched Fraction of Hydroalcoholic Extract of Picrorhiza kurroa.Exploring dual inhibitors for STAT1 and STAT5 receptors utilizing virtual screening and dynamics simulation validationIdentification of 16,25--diacetyl-cucurbitane F and 25--acetyl-23,24-dihydrocucurbitacin F as novel anti-cancer chemicals
P2860
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P2860
Cucurbitacin IIa: a novel class of anti-cancer drug inducing non-reversible actin aggregation and inhibiting survivin independent of JAK2/STAT3 phosphorylation.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Cucurbitacin IIa: a novel clas ...... of JAK2/STAT3 phosphorylation.
@en
Cucurbitacin IIa: a novel clas ...... of JAK2/STAT3 phosphorylation.
@nl
type
label
Cucurbitacin IIa: a novel clas ...... of JAK2/STAT3 phosphorylation.
@en
Cucurbitacin IIa: a novel clas ...... of JAK2/STAT3 phosphorylation.
@nl
prefLabel
Cucurbitacin IIa: a novel clas ...... of JAK2/STAT3 phosphorylation.
@en
Cucurbitacin IIa: a novel clas ...... of JAK2/STAT3 phosphorylation.
@nl
P2093
P2860
P356
P1476
Cucurbitacin IIa: a novel clas ...... of JAK2/STAT3 phosphorylation.
@en
P2093
P2860
P2888
P304
P356
10.1038/BJC.2011.10
P407
P577
2011-02-08T00:00:00Z
P5875
P6179
1047042983