Gambogic acid-induced degradation of mutant p53 is mediated by proteasome and related to CHIP.
about
Targeting Oncogenic Mutant p53 for Cancer TherapyCurrent Understanding on EGFR and Wnt/β-Catenin Signaling in Glioma and Their Possible CrosstalkA Decade of Boon or Burden: What Has the CHIP Ever Done for Cellular Protein Quality Control Mechanism Implicated in Neurodegeneration and Aging?Sorafenib inhibits proliferation and invasion of human hepatocellular carcinoma cells via up-regulation of p53 and suppressing FoxM1.MiR-1178 promotes the proliferation, G1/S transition, migration and invasion of pancreatic cancer cells by targeting CHIP.Small-Molecule NSC59984 Restores p53 Pathway Signaling and Antitumor Effects against Colorectal Cancer via p73 Activation and Degradation of Mutant p53.Crude Extracts, Flavokawain B and Alpinetin Compounds from the Rhizome of Alpinia mutica Induce Cell Death via UCK2 Enzyme Inhibition and in Turn Reduce 18S rRNA Biosynthesis in HT-29 Cells.It Takes 15 to Tango: Making Sense of the Many Ubiquitin Ligases of p53.Silencing NOTCH signaling causes growth arrest in both breast cancer stem cells and breast cancer cells.Essential Roles of E3 Ubiquitin Ligases in p53 Regulation.Prenylated caged xanthones: chemistry and biology.Mutant p53 in Cancer: Accumulation, Gain-of-Function, and Therapy.Gambogic acid promotes apoptosis and resistance to metastatic potential in MDA-MB-231 human breast carcinoma cells.Studies on chemical-structure modification and structure-activity relationship of gambogic acid derivatives at carbon(34).Gambogic acid as a non-competitive inhibitor of ATP-binding cassette transporter B1 reverses the multidrug resistance of human epithelial cancers by promoting ATP-binding cassette transporter B1 protein degradation.Apoptotic effect of the selective PPARβ/δ agonist GW501516 in invasive bladder cancer cells.Molecularly targeted therapies for p53-mutant cancers.An in silico approach in predicting the possible mechanism involving restoration of wild-type p53 functions by small molecular weight compounds in tumor cells expressing R273H mutant p53.
P2860
Q26770856-9957D40A-A9FC-41E0-8B2B-B0C58996A37DQ26865911-CFBC2BE1-4DE8-4A90-A896-F44FB04A6719Q28078724-72307DCF-50C1-4A8B-B2D4-FE9DB846475CQ35080145-44291F46-94D8-4759-ACAB-4598F2B9BB08Q35551998-6F35FA5F-C85B-4137-9C41-2F8A480E2CB0Q36070528-45BD8AAC-B026-4A5E-B073-67B69BFF51E1Q36254067-0A1579D4-8C95-4084-B49A-91ADE2145559Q36387588-840863BB-944F-4A33-9900-72BED7149BDDQ37323067-276E0820-F9EE-4F36-9548-406424B80559Q37691041-5E1A8A7D-F609-478E-89D4-4A104904C74DQ37971139-4C2C81E4-9C3D-465B-A718-82038DE21698Q39229004-9DADE83C-B87F-4DB0-8798-1CD6989463F4Q39235972-D9A41D98-9230-4D64-9B75-DE2B12CBB036Q39256515-9662A8BB-49D6-48F7-8DB9-40C048898AE6Q39320594-C7ACD39B-15E9-4339-8899-66A74C39D7B1Q39379510-EA637903-162E-4322-ADAD-C67829E3CBA1Q39393193-7758364E-2F21-4EA2-84F3-A84387AA7CFBQ49481527-54765EB0-EC82-4925-A83F-4EB1AED17099
P2860
Gambogic acid-induced degradation of mutant p53 is mediated by proteasome and related to CHIP.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Gambogic acid-induced degradat ...... roteasome and related to CHIP.
@en
Gambogic acid-induced degradat ...... roteasome and related to CHIP.
@nl
type
label
Gambogic acid-induced degradat ...... roteasome and related to CHIP.
@en
Gambogic acid-induced degradat ...... roteasome and related to CHIP.
@nl
prefLabel
Gambogic acid-induced degradat ...... roteasome and related to CHIP.
@en
Gambogic acid-induced degradat ...... roteasome and related to CHIP.
@nl
P2093
P2860
P356
P1476
Gambogic acid-induced degradat ...... roteasome and related to CHIP.
@en
P2093
Hong-yan Gu
Jing-jing Rong
Mei-juan Zou
Qi-dong You
Qing-long Guo
P2860
P304
P356
10.1002/JCB.22941
P577
2011-02-01T00:00:00Z