Docking, synthesis, and in vitro evaluation of antimitotic estrone analogs.
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Antimitotic drugs in the treatment of cancerIn vitro evaluation of ESE-15-ol, an estradiol analogue with nanomolar antimitotic and carbonic anhydrase inhibitory activitySignaling pathways of ESE-16, an antimitotic and anticarbonic anhydrase estradiol analog, in breast cancer cellsAn estrogen analogue and promising anticancer agent refrains from inducing morphological damage and reactive oxygen species generation in erythrocytes, fibrin and platelets: a pilot studyUltrastructural changes of erythrocytes in whole blood after exposure to prospective in silico-designed anticancer agents: a qualitative case studySulphamoylated 2-methoxyestradiol analogues induce apoptosis in adenocarcinoma cell lines.Novel estradiol analogue induces apoptosis and autophagy in esophageal carcinoma cells.A 2-methoxyestradiol bis-sulphamoylated derivative induces apoptosis in breast cell linesInduction of the intrinsic apoptotic pathway via a new antimitotic agent in an esophageal carcinoma cell lineA bis-sulphamoylated estradiol derivative induces ROS-dependent cell cycle abnormalities and subsequent apoptosis.Ex vivo apoptotic and autophagic influence of an estradiol analogue on platelets.Molecular crosstalk between apoptosis and autophagy induced by a novel 2-methoxyestradiol analogue in cervical adenocarcinoma cells.In vitro assessment of a computer-designed potential anticancer agent in cervical cancer cells.Autophagy induced by a sulphamoylated estrone analogue contributes to its cytotoxic effect on breast cancer cells.Discovery and Development of the Aryl O-Sulfamate Pharmacophore for Oncology and Women's Health.Inhibition of proliferation and invasion in 2D and 3D models by 2-methoxyestradiol in human melanoma cells.Novel in silico-designed estradiol analogues are cytotoxic to a multidrug-resistant cell line at nanomolar concentrations.17-beta-estradiol analog inhibits cell proliferation by induction of apoptosis in breast cell lines.In vitro changes in mitochondrial potential, aggresome formation and caspase activity by a novel 17-β-estradiol analogue in breast adenocarcinoma cells.Sulphamoylated estradiol analogue induces antiproliferative activity and apoptosis in breast cell lines.2-Methoxyestradiol-bis-sulphamate refrains from inducing apoptosis and autophagy in a non-tumorigenic breast cell lineEx vivo Determination of an Estradiol Analogue-Induced Changes on Platelet Morphology and Angiogenic Biomarkers.An overview of the role of platelets in angiogenesis, apoptosis and autophagy in chronic myeloid leukaemia.In vitro effects of an in silico-modelled 17β-estradiol derivative in combination with dichloroacetic acid on MCF-7 and MCF-12A cells.Comparative investigation of the in vitro inhibitory potencies of 13-epimeric estrones and D-secoestrones towards 17β-hydroxysteroid dehydrogenase type 1.The in vitro effects of a novel estradiol analog on cell proliferation and morphology in human epithelial cervical carcinoma.
P2860
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P2860
Docking, synthesis, and in vitro evaluation of antimitotic estrone analogs.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Docking, synthesis, and in vitro evaluation of antimitotic estrone analogs.
@en
Docking, synthesis, and in vitro evaluation of antimitotic estrone analogs.
@nl
type
label
Docking, synthesis, and in vitro evaluation of antimitotic estrone analogs.
@en
Docking, synthesis, and in vitro evaluation of antimitotic estrone analogs.
@nl
prefLabel
Docking, synthesis, and in vitro evaluation of antimitotic estrone analogs.
@en
Docking, synthesis, and in vitro evaluation of antimitotic estrone analogs.
@nl
P2093
P2860
P1476
Docking, synthesis, and in vitro evaluation of antimitotic estrone analogs.
@en
P2093
Andre Stander
Annie Joubert
Fourie Joubert
P2860
P304
P356
10.1111/J.1747-0285.2010.01064.X
P577
2011-01-19T00:00:00Z