Polyclonality of BRAF mutations in primary melanoma and the selection of mutant alleles during progression.
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Assessment of BRAF V600E mutation status by immunohistochemistry with a mutation-specific monoclonal antibodyIntra- and inter-tumor heterogeneity of BRAF(V600E))mutations in primary and metastatic melanomaDiscrepant alterations in main candidate genes among multiple primary melanomasGenetics and epigenetics of the skin meet deep sequence.A brief history of melanoma: from mummies to mutationsThe clinical response to vemurafenib in a patient with a rare BRAFV600DK601del mutation-positive melanoma.Clinical utility of a blood-based BRAF(V600E) mutation assay in melanomaAutomated universal BRAF state detection within the activation segment in skin metastases by pyrosequencing-based assay U-BRAF(V600)Tumor homogeneity between primary and metastatic sites for BRAF status in metastatic melanoma determined by immunohistochemical and molecular testingBRAF and NRAS mutations are heterogeneous and not mutually exclusive in nodular melanomaA mutant BRAF V600E-specific immunohistochemical assay: correlation with molecular mutation status and clinical outcome in colorectal cancer.A novel approach for the detection and genetic analysis of live melanoma circulating tumor cells.BRAF in Melanoma: Pathogenesis, Diagnosis, Inhibition, and ResistanceMutation analysis of BRAF and KIT in circulating melanoma cells at the single cell level.NRAS (Q61R), BRAF (V600E) immunohistochemistry: a concomitant tool for mutation screening in melanomas.BRAFV600E immunopositive melanomas show low frequency of heterogeneity and association with epithelioid tumor cells: a STROBE-compliant article.Allele frequencies of BRAFV600 mutations in primary melanomas and matched metastases and their relevance for BRAF inhibitor therapy in metastatic melanomaKRAS gene mutations are more common in colorectal villous adenomas and in situ carcinomas than in carcinomas.Single molecule molecular inversion probes for targeted, high-accuracy detection of low-frequency variationGNAS gene mutation may be present only transiently during colorectal tumorigenesisRare BRAF mutations in melanoma patients: implications for molecular testing in clinical practice.Heterogeneous distribution of BRAF/NRAS mutations among Italian patients with advanced melanoma.In situ Protein Detection for Companion Diagnostics.Mutation landscape in melanoma patients clinical implications of heterogeneity of BRAF mutations.Inter- and intra-patient heterogeneity of response and progression to targeted therapy in metastatic melanoma.Heterogeneity and frequency of BRAF mutations in primary melanoma: Comparison between molecular methods and immunohistochemistry.Acquired and intrinsic BRAF inhibitor resistance in BRAF V600E mutant melanoma.MAP kinase signaling and inhibition in melanoma.Vemurafenib in melanoma.Clinical and therapeutic implications of BRAF mutation heterogeneity in metastatic melanoma.A quantitative allele-specific PCR test for the BRAF V600E mutation using a single heterozygous control plasmid for quantitation: a model for qPCR testing without standard curves.Plasma Circulating Tumor DNA Levels for the Monitoring of Melanoma Patients: Landscape of Available Technologies and Clinical Applications.Specifically targeting ERK1 or ERK2 kills melanoma cellsComparison of Three BRAF Mutation Tests in Formalin-Fixed Paraffin Embedded Clinical Samples.MET expression in melanoma correlates with a lymphangiogenic phenotype.Stability of BRAF V600E mutation in metastatic melanoma: new insights for therapeutic success?Reply: Intra-patient heterogeneity of BRAF mutation status: fact or fiction?Intratumor and Intertumor Heterogeneity in Melanoma.Melanoma: Genetic Abnormalities, Tumor Progression, Clonal Evolution and Tumor Initiating Cells.Tumor cell-intrinsic phenotypic plasticity facilitates adaptive cellular reprogramming driving acquired drug resistance.
P2860
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P2860
Polyclonality of BRAF mutations in primary melanoma and the selection of mutant alleles during progression.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Polyclonality of BRAF mutation ...... nt alleles during progression.
@en
Polyclonality of BRAF mutation ...... nt alleles during progression.
@nl
type
label
Polyclonality of BRAF mutation ...... nt alleles during progression.
@en
Polyclonality of BRAF mutation ...... nt alleles during progression.
@nl
prefLabel
Polyclonality of BRAF mutation ...... nt alleles during progression.
@en
Polyclonality of BRAF mutation ...... nt alleles during progression.
@nl
P2093
P2860
P356
P1476
Polyclonality of BRAF mutation ...... nt alleles during progression.
@en
P2093
A Uchiyama
K Sakaizawa
P2860
P2888
P304
P356
10.1038/SJ.BJC.6606072
P407
P577
2011-01-11T00:00:00Z