Serum- and glucocorticoid-inducible kinase 1 (SGK1) controls Notch1 signaling by downregulation of protein stability through Fbw7 ubiquitin ligase. - Wikidata - awgldk - TriplyDB

Serum- and glucocorticoid-inducible kinase 1 (SGK1) controls Notch1 signaling by downregulation of protein stability through Fbw7 ubiquitin ligase.

Serum- and glucocorticoid-inducible kinase 1 (SGK1) controls Notch1 signaling by downregulation of protein stability through Fbw7 ubiquitin ligase.

http://www.wikidata.org/entity/Q39621502

about

PI3K-dependent phosphorylation of Fbw7 modulates substrate degradation and activity Frequent mutation of histone-modifying genes in non-Hodgkin lymphoma Fbxw7 Tumor Suppressor: A Vital Regulator Contributes to Human Tumorigenesis What a tangled web we weave: emerging resistance mechanisms to inhibition of the phosphoinositide 3-kinase pathway Fbxw7 controls angiogenesis by regulating endothelial Notch activity Diffuse large B-cell lymphoma: can genomics improve treatment options for a curable cancer?Nuclear retention of Fbw7 by specific inhibitors of nuclear export leads to Notch1 degradation in pancreatic cancer Phosphorylation of nicastrin by SGK1 leads to its degradation through lysosomal and proteasomal pathways.Estrogen receptor beta impacts hormone-induced alternative mRNA splicing in breast cancer cells.Dual regulation of notch1 signaling pathway by adaptor protein fe65 Single nucleotide polymorphism microarray analysis in cortisol-secreting adrenocortical adenomas identifies new candidate genes and pathways.Tumor suppressor functions of FBW7 in cancer development and progression.Wnt5a controls Notch1 signaling through CaMKII-mediated degradation of the SMRT corepressor protein MicroRNAs and Glucocorticoid-Induced Apoptosis in Lymphoid Malignancies Low SGK1 expression in human adrenocortical tumors is associated with ACTH-independent glucocorticoid secretion and poor prognosis.Regulation of Notch1 signaling by Delta-like ligand 1 intracellular domain through physical interaction.Role of Notch signaling pathway in pancreatic cancer.Therapeutic potential of serum and glucocorticoid inducible kinase inhibition.In vivo effects of dexamethasone on blood gene expression in ataxia telangiectasia.The stability of Fbw7α in M-phase requires its phosphorylation by PKC.PI3K/mTOR inhibition upregulates NOTCH-MYC signalling leading to an impaired cytotoxic response.Integrating genomic alterations in diffuse large B-cell lymphoma identifies new relevant pathways and potential therapeutic targets.Dexamethasone suppresses cochlear Hes1 expression after noise exposure.Physiological functions of FBW7 in cancer and metabolism.

P2860

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P2860

Serum- and glucocorticoid-inducible kinase 1 (SGK1) controls Notch1 signaling by downregulation of protein stability through Fbw7 ubiquitin ligase.

http://www.wikidata.org/entity/Q39621502

description

2010 nî lūn-bûn

@nan

2010年の論文

@ja

2010年論文

@yue

2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

2010年论文

@zh

2010年论文

@zh-cn

name

Serum- and glucocorticoid-indu ...... through Fbw7 ubiquitin ligase.

@en

Serum- and glucocorticoid-inducible kinase 1

@nl

type

label

Serum- and glucocorticoid-indu ...... through Fbw7 ubiquitin ligase.

@en

Serum- and glucocorticoid-inducible kinase 1

@nl

prefLabel

Serum- and glucocorticoid-indu ...... through Fbw7 ubiquitin ligase.

@en

Serum- and glucocorticoid-inducible kinase 1

@nl

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P1433

Journal of Cell Science

P1476

Serum- and glucocorticoid-indu ...... through Fbw7 ubiquitin ligase.

@en

P2093

Eui-Ju Choi

http://www.w3.org/2001/XMLSchema#string

Eun-Jung Ann

http://www.w3.org/2001/XMLSchema#string

Florian Lang

http://www.w3.org/2001/XMLSchema#string

Hee-Sae Park

http://www.w3.org/2001/XMLSchema#string

Hwa-Young Kim

http://www.w3.org/2001/XMLSchema#string

Jane Jung

http://www.w3.org/2001/XMLSchema#string

Ji-Ae Hong

http://www.w3.org/2001/XMLSchema#string

Ji-Hye Yoon

http://www.w3.org/2001/XMLSchema#string

Ji-Seon Ahn

http://www.w3.org/2001/XMLSchema#string

Jung-Soon Mo

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P304

100-112

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P31

scholarly article

P356

10.1242/JCS.073924

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P407

P433

Pt 1

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P478

124

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P577

2010-12-08T00:00:00Z

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49673747

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21147854

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