Glycogen synthase kinase-3 (GSK-3) inhibition attenuates hepatocyte lipoapoptosis. - Wikidata - awgldk - TriplyDB

Glycogen synthase kinase-3 (GSK-3) inhibition attenuates hepatocyte lipoapoptosis.

Glycogen synthase kinase-3 (GSK-3) inhibition attenuates hepatocyte lipoapoptosis.

http://www.wikidata.org/entity/Q39621569

about

A liver full of JNK: signaling in regulation of cell function and disease pathogenesis, and clinical approaches Cell biology. Metabolic control of cell death Autophagy protects against palmitate-induced apoptosis in hepatocytes Signaling dynamics of palmitate-induced ER stress responses mediated by ATF4 in HepG2 cells Mechanisms of lipotoxicity in NAFLD and clinical implications Resveratrol enhances palmitate-induced ER stress and apoptosis in cancer cells cAMP-guanine exchange factor protection from bile acid-induced hepatocyte apoptosis involves glycogen synthase kinase regulation of c-Jun NH2-terminal kinase Mechanisms of lysophosphatidylcholine-induced hepatocyte lipoapoptosis Toyocamycin attenuates free fatty acid-induced hepatic steatosis and apoptosis in cultured hepatocytes and ameliorates nonalcoholic fatty liver disease in mice.Critical role for mixed-lineage kinase 3 in acetaminophen-induced hepatotoxicity.Post-transcriptional activation of PPAR alpha by KLF6 in hepatic steatosis.Glycycoumarin inhibits hepatocyte lipoapoptosis through activation of autophagy and inhibition of ER stress/GSK-3-mediated mitochondrial pathway.Cysteine aggravates palmitate-induced cell death in hepatocytes.PUMA, a critical mediator of cell death--one decade on from its discovery.Regulation of drug-induced liver injury by signal transduction pathways: critical role of mitochondria.Cdc42 and Rac1 are major contributors to the saturated fatty acid-stimulated JNK pathway in hepatocytes.c-Jun N-terminal kinase-mediated Rubicon expression enhances hepatocyte lipoapoptosis and promotes hepatocyte ballooning.Lipotoxicity pathways intersect in hepatocytes: Endoplasmic reticulum stress, c-Jun N-terminal kinase-1, and death receptors.Sab (Sh3bp5) dependence of JNK mediated inhibition of mitochondrial respiration in palmitic acid induced hepatocyte lipotoxicity.Involvement of endoplasmic reticulum stress in all-trans-retinal-induced retinal pigment epithelium degeneration.Degradation of Keap1 activates BH3-only proteins Bim and PUMA during hepatocyte lipoapoptosis Hepatitis C Virus Infection Increases c-Jun N-Terminal Kinase (JNK) Phosphorylation and Accentuates Hepatocyte Lipoapoptosis.Who pulls the trigger: JNK activation in liver lipotoxicity?Biliverdin Reductase A Attenuates Hepatic Steatosis by Inhibition of Glycogen Synthase Kinase (GSK) 3β Phosphorylation of Serine 73 of Peroxisome Proliferator-activated Receptor (PPAR) α.P38 MAPK Pharmacological Inhibitor SB203580 Alleviates Total Parenteral Nutrition-Induced Loss of Intestinal Barrier Function but Promotes Hepatocyte Lipoapoptosis.HIF-1α expression as a protective strategy of HepG2 cells against fatty acid-induced toxicity.To die or not to die: death signaling in nonalcoholic fatty liver disease.Apoptosis and non-alcoholic fatty liver diseases.

P2860

Q28392033-7A4CB396-11A4-4385-945B-BB1260AA4930 Q28397089-BCB0B444-F1E8-478B-94A5-2DB6AECD8ABB Q33712340-8AE76F84-1ADB-4AFF-BCDA-EC25480A70A1 Q34557052-F77DD741-41F3-40A1-B526-BA9689E93C23 Q35132916-3D2E2902-8D0F-4222-BED9-6135FF938A69 Q35462357-B0D81EAF-12D4-4DF7-B824-6949F9AA990D Q35760713-384641EE-EC84-4EE2-9E01-D0F422AB5C8E Q35939383-8D429D4A-EEFC-4884-B0EF-7C6F2A91EB54 Q36302806-4D891800-A326-46D6-BB9C-62FDEBD9CCCE Q36335609-F8C967A3-CFE0-462F-8784-5F49B353047C Q36781204-6B2F096A-2EEB-4C2A-A396-ECCEB61F3441 Q37454201-2E67A5B1-607F-43F7-B60D-D1ED90A66F5A Q37726495-FC6B1D4B-E77E-4D03-BA31-011C54B590E6 Q38045794-6B34B914-1896-44D4-B460-BFB8C6508C14 Q38085856-9E0FF802-17F3-4FD7-B4D7-7CE0F6E5C926 Q38594016-A94AEB8D-A9FE-4E5D-84FB-03F3687EABA9 Q38747634-E7EA9B0D-72D3-4416-A720-1E7BB398297C Q38759104-E7FBB530-687F-4351-B097-518A6644C6C3 Q38911401-B2A5EBCE-7211-4133-B6A6-908EC27F3B03 Q38946467-12B2881C-06A0-4EA7-B7CC-F64BF3EF40CA Q39000961-E6268395-54D6-4A0D-B4DE-80DA6B0469C5 Q41867049-92939E8C-3DFA-4BC7-96C3-7B343F2CE556 Q42592098-347D806E-CD5C-435C-A296-281DB219494A Q46171319-6C014D40-FF33-4900-83A9-948E2B796E3B Q51132126-2530D52D-CFE2-4E17-B123-5F4591ECEEAC Q51760102-FA1C31F3-56FA-42AA-8BE7-55B0FF401D1C Q54119547-193CD790-9082-497C-B22F-19DBA6EE357E Q55503094-E2BD0536-4652-4C60-9BE9-C5B5B6AA4139

P2860

Glycogen synthase kinase-3 (GSK-3) inhibition attenuates hepatocyte lipoapoptosis.

http://www.wikidata.org/entity/Q39621569

description

2010 nî lūn-bûn

@nan

2010年の論文

@ja

2010年論文

@yue

2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

2010年论文

@zh

2010年论文

@zh-cn

name

Glycogen synthase kinase-3 (GSK-3) inhibition attenuates hepatocyte lipoapoptosis.

@en

Glycogen synthase kinase-3

@nl

type

label

Glycogen synthase kinase-3 (GSK-3) inhibition attenuates hepatocyte lipoapoptosis.

@en

Glycogen synthase kinase-3

@nl

prefLabel

Glycogen synthase kinase-3 (GSK-3) inhibition attenuates hepatocyte lipoapoptosis.

@en

Glycogen synthase kinase-3

@nl

P1433

Q39621569-9203DF09-3645-474E-A71A-838E9A382EBB

P1476

Q39621569-0E3A9F71-9116-4193-86C4-35A4D800B011

P2093

Q39621569-05575C13-7D9D-4596-90E6-11E50E0687D4

Q39621569-2367F6B3-ADEE-4486-9C2C-2C078E014379

Q39621569-AF0F76CA-A9B9-4F64-8414-E7254AC51BDC

Q39621569-B2D860C5-FDEB-4636-9B09-952ED596E42B

Q39621569-C5462078-5237-42DD-8DF0-13C7F315764E

Q39621569-F8EF519F-8572-4389-A39B-20693A15AD0A

Q39621569-FE1A4C1D-5B82-4D2B-9A39-0BEA08050B41

P2860

Q39621569-0035FA54-E4FD-41C1-92E4-F15833C37A81

Q39621569-00C38C60-2F33-4D64-BE02-38497E08F6E6

Q39621569-016B63A4-0F96-42BF-AFA5-2D99163E95F0

Q39621569-05426CFC-DFB4-4466-80C0-4091EBFE8FA2

Q39621569-06143AAF-7864-41B0-9BB4-E984E86267C7

Q39621569-0D2B35C9-6A02-49A5-9FDC-56230D7CCFCB

Q39621569-1450739C-6BC4-4374-A239-4ED38D6740D4

Q39621569-16C39EC3-8143-4C3C-B2A7-7363E43DD9EF

Q39621569-17F10DB4-567C-4AE7-93E2-CCE2EE58E6F6

Q39621569-25B2E906-EF4A-4F1F-B1F7-6356FC547BE0

P304

Q39621569-759C647E-C1A2-4FC0-9F10-B63608637C94

P31

Q39621569-AE6AB207-EDCE-492E-9E40-F51D7EAFB227

P356

Q39621569-87D76C9C-8536-418B-834A-31BAAB001426

P433

Q39621569-93BB4E3B-CF45-4248-8B76-4B9FFAA8F84E

P478

Q39621569-DBB4967B-55C2-40A5-ABA2-AE02FC1FB528

P50

Q39621569-C66C4DCC-898F-443C-82EF-9F775A3C0391

P577

Q39621569-3966939E-2FE5-4A08-A550-F2B670689F11

P5875

Q39621569-67AFC5B6-80A3-4CC7-BD1D-96D321B26FF7

P698

Q39621569-247748A1-2044-4272-804D-500A0995E2B9

P932

Q39621569-EBD33FC0-1AEC-4D8D-92CA-993E817D6ADD

P356

J.JHEP.2010.09.039

P1433

Journal of Hepatology

P1476

Glycogen synthase kinase-3 (GSK-3) inhibition attenuates hepatocyte lipoapoptosis.

@en

P2093

Daniel D Billadeau

http://www.w3.org/2001/XMLSchema#string

Nafisa A Elmi

http://www.w3.org/2001/XMLSchema#string

Nathan W Werneburg

http://www.w3.org/2001/XMLSchema#string

Samar H Ibrahim

http://www.w3.org/2001/XMLSchema#string

Sophie C Cazanave

http://www.w3.org/2001/XMLSchema#string

Steven F Bronk

http://www.w3.org/2001/XMLSchema#string

Yuko Akazawa

http://www.w3.org/2001/XMLSchema#string

P2860

Glycogen synthase kinase-3 regulates mitochondrial outer membrane permeabilization and apoptosis by destabilization of MCL-1

Cytokeratin-18 fragment levels as noninvasive biomarkers for nonalcoholic steatohepatitis: a multicenter validation study

Requirement for glycogen synthase kinase-3beta in cell survival and NF-kappaB activation

Maintenance of pluripotency in human and mouse embryonic stem cells through activation of Wnt signaling by a pharmacological GSK-3-specific inhibitor

Prevalence of hepatic steatosis in an urban population in the United States: impact of ethnicity

The natural history of nonalcoholic fatty liver disease: a population-based cohort study

A trip to the ER: coping with stress

Valproate attenuates accelerated atherosclerosis in hyperglycemic apoE-deficient mice: evidence in support of a role for endoplasmic reticulum stress and glycogen synthase kinase-3 in lesion development and hepatic steatosis.

Silencing glycogen synthase kinase-3beta inhibits acetaminophen hepatotoxicity and attenuates JNK activation and loss of glutamate cysteine ligase and myeloid cell leukemia sequence 1.

Toxic bile salts induce rodent hepatocyte apoptosis via direct activation of Fas.

P304

765-772

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1016/J.JHEP.2010.09.039

http://www.w3.org/2001/XMLSchema#string

P433

4

http://www.w3.org/2001/XMLSchema#string

P478

54

http://www.w3.org/2001/XMLSchema#string

P50

Gregory J Gores

P577

2010-11-23T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

49673419

http://www.w3.org/2001/XMLSchema#string

P698

21147505

http://www.w3.org/2001/XMLSchema#string

P932

3060963

http://www.w3.org/2001/XMLSchema#string