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A new ceramide from Suillus luteus and its cytotoxic activity against human melanoma cells.Cytotoxic activities of flavonoid glycoside acetates from Consolida oliveriana.Synthesis and antitumor molecular mechanism of agents based on amino 2-(3',4',5'-trimethoxybenzoyl)benzo[b]furan: inhibition of tubulin and induction of apoptosis.Eupatorin-induced cell death in human leukemia cells is dependent on caspases and activates the mitogen-activated protein kinase pathway.Antiproliferative activity and apoptosis induction by 3',4'-dibenzyloxyflavonol on human leukemia cells.Gardenin B-induced cell death in human leukemia cells involves multiple caspases but is independent of the generation of reactive oxygen species.Sesquiterpenoids Isolated from Two Species of the Asteriscus Alliance.The eudesmanolide tanapsin from Tanacetum oshanahanii and its acetate induce cell death in human tumor cells through a mechanism dependent on reactive oxygen species.Isolation from Eucalyptus occidentalis and identification of a new kaempferol derivative that induces apoptosis in human myeloid leukemia cells.Induction of G2/M phase arrest and apoptosis by the flavonoid tamarixetin on human leukemia cells.Secondary metabolites from two species of Tolpis and their biological activities.5,7,3'-Trihydroxy-3,4'-dimethoxyflavone inhibits the tubulin polymerization and activates the sphingomyelin pathway.Pregnane steroidal glycosides and their cytostatic activities.Melatonin decreases cell proliferation and induces melanogenesis in human melanoma SK-MEL-1 cells.Naturally occurring asteriscunolide A induces apoptosis and activation of mitogen-activated protein kinase pathway in human tumor cell lines.5,7,3'-trihydroxy-3,4'-dimethoxyflavone-induced cell death in human leukemia cells is dependent on caspases and activates the MAPK pathway.Betuletol 3-methyl ether induces G(2)-M phase arrest and activates the sphingomyelin and MAPK pathways in human leukemia cells.Synthesis of novel spirostanic saponins and their cytotoxic activity.Acetyl derivative of quercetin 3-methyl ether-induced cell death in human leukemia cells is amplified by the inhibition of ERK.A homo-isoflavonoid and a cytotoxic saponin from Dracaena draco.Isolation, structure elucidation, total synthesis, and evaluation of new natural and synthetic ceramides on human SK-MEL-1 melanoma cells.Phenylbenzopyrones structure-activity studies identify betuletol derivatives as potential antitumoral agents.Design, synthesis, and biological evaluation of hybrid molecules containing alpha-methylene-gamma-butyrolactones and alpha-bromoacryloyl moieties.Sesquiterpenoids from Pulicaria canariensis and their cytotoxic activities.Cladocalol, a pentacyclic 28-nor-triterpene from Eucalyptus cladocalyx with cytotoxic activity.Icogenin, a new cytotoxic steroidal saponin isolated from Dracaena draco.Design, synthesis, and biological evaluation of hybrid molecules containing alpha-methylene-gamma-butyrolactones and polypyrrole minor groove binders.Synthesis and antiproliferative activity of a new compound containing an alpha-methylene-gamma-lactone group.Design, synthesis and antiproliferative activity of novel heterobivalent hybrids based on imidazo[2,1-b][1,3,4]thiadiazole and imidazo[2,1-b][1,3]thiazole scaffolds.Diacylglycerol rather than Ca2+ mediates GnRH inhibition of FSH induced steroidogenesis in ovarian granulosa cells.alpha-Bromoacrylamido N-substituted isatin derivatives as potent inducers of apoptosis in human myeloid leukemia cells.Chemical constituents of Tolpis species.New lanostanoids from the fungus Ganoderma concinna.Sesquiterpene lactones from Gonospermum gomerae and G. fruticosum and their cytotoxic activities.Sesquiterpenoid derivatives from Gonospermum elegans and their cytotoxic activity for HL-60 human promyelocytic cells.Melatonin prevents apoptosis and enhances HSP27 mRNA expression induced by heat shock in HL-60 cells: possible involvement of the MT2 receptor.Identification and quantitation of allelochemicals from the lichen Lethariella canariensis: phytotoxicity and antioxidative activity.Potent induction of apoptosis by germacranolide sesquiterpene lactones on human myeloid leukemia cells.Enantioselective synthesis and biological activity of (3S,4R)- and (3S,4S)-3-hydroxy-4-hydroxymethyl- 4-butanolides in relation to PGE2.Lanostanoid triterpenes from Laetiporus sulphureus and apoptosis induction on HL-60 human myeloid leukemia cells.
P50
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P50
description
hulumtues
@sq
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Francisco Estévez
@ast
Francisco Estévez
@en
Francisco Estévez
@es
Francisco Estévez
@nl
Francisco Estévez
@sl
type
label
Francisco Estévez
@ast
Francisco Estévez
@en
Francisco Estévez
@es
Francisco Estévez
@nl
Francisco Estévez
@sl
prefLabel
Francisco Estévez
@ast
Francisco Estévez
@en
Francisco Estévez
@es
Francisco Estévez
@nl
Francisco Estévez
@sl
P1053
K-5125-2014
P106
P21
P31
P3829
P496
0000-0002-9728-2774