Chemoattractant-induced signaling via the Ras-ERK and PI3K-Akt networks, along with leukotriene C4 release, is dependent on the tyrosine kinase Lyn in IL-5- and IL-3-primed human blood eosinophils.
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IL-5 induces suspended eosinophils to undergo unique global reorganization associated with priming.Cholesterol selectively regulates IL-5 induced mitogen activated protein kinase signaling in human eosinophilsIdentification of JAK2 as a mediator of FIP1L1-PDGFRA-induced eosinophil growth and function in CELSimvastatin Inhibits IL-5-Induced Chemotaxis and CCR3 Expression of HL-60-Derived and Human Primary EosinophilsIL-3 and TNFα increase Thymic Stromal Lymphopoietin Receptor (TSLPR) expression on eosinophils and enhance TSLP-stimulated degranulationAltered AKT1 and MAPK1 gene expression on peripheral blood mononuclear cells and correlation with T-helper-transcription factors in systemic lupus erythematosus patientsHuman airway eosinophils exhibit preferential reduction in STAT signaling capacity and increased CISH expression.Lyn mitigates mouse airway remodeling by downregulating the TGF-β3 isoform in house dust mite models.Lyn regulates mucus secretion and MUC5AC via the STAT6 signaling pathway during allergic airway inflammation.Reconstitution of anti-allergic activities of PG102 derived from Actinidia arguta by combining synthetic chemical compounds.Essential Mechanisms of Differential Activation of Eosinophils by IL-3 Compared to GM-CSF and IL-5.Kaempferol suppresses eosionphil infiltration and airway inflammation in airway epithelial cells and in mice with allergic asthma.Potent synergistic effect of IL-3 and TNF on matrix metalloproteinase 9 generation by human eosinophilsProtein Translation and Signaling in Human EosinophilsLyn mediates FIP1L1-PDGFRA signal pathway facilitating IL-5RA intracellular signal through FIP1L1-PDGFRA/JAK2/Lyn/Akt network complex in CEL.Farnesyltransferase Inhibition Exacerbates Eosinophilic Inflammation and Airway Hyperreactivity in Mice with Experimental Asthma: The Complex Roles of Ras GTPase and Farnesylpyrophosphate in Type 2 Allergic Inflammation.The antimicrobial peptide LL-37 induces synthesis and release of cysteinyl leukotrienes from human eosinophils--implications for asthma.
P2860
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P2860
Chemoattractant-induced signaling via the Ras-ERK and PI3K-Akt networks, along with leukotriene C4 release, is dependent on the tyrosine kinase Lyn in IL-5- and IL-3-primed human blood eosinophils.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
Chemoattractant-induced signal ...... rimed human blood eosinophils.
@en
Chemoattractant-induced signal ...... rimed human blood eosinophils.
@nl
type
label
Chemoattractant-induced signal ...... rimed human blood eosinophils.
@en
Chemoattractant-induced signal ...... rimed human blood eosinophils.
@nl
prefLabel
Chemoattractant-induced signal ...... rimed human blood eosinophils.
@en
Chemoattractant-induced signal ...... rimed human blood eosinophils.
@nl
P2860
P356
P1476
Chemoattractant-induced signal ...... rimed human blood eosinophils.
@en
P2093
Paul J Bertics
Yiming Zhu
P2860
P304
P356
10.4049/JIMMUNOL.1000955
P407
P577
2010-11-24T00:00:00Z