18th Sir Hans Krebs lecture. Knowledge-based protein modelling and design.
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Comparative modelling of barley-grain aspartic proteinase: A structural rationale for observed hydrolytic specificityKM+, a mannose-binding lectin from Artocarpus integrifolia: amino acid sequence, predicted tertiary structure, carbohydrate recognition, and analysis of the beta-prism foldThree-dimensional model and quaternary structure of the human eye lens protein gamma S-crystallin based on beta- and gamma-crystallin X-ray coordinates and ultracentrifugationMolecular models of NS3 protease variants of the Hepatitis C virusStructural basis of regulation and substrate specificity of protein kinase CK2 deduced from the modeling of protein-protein interactionsAn unusual carbohydrate binding site revealed by the structures of two Maackia amurensis lectins complexed with sialic acid-containing oligosaccharidesStructural basis for pterin antagonism in nitric-oxide synthase. Development of novel 4-oxo-pteridine antagonists of (6R)-5,6,7,8-tetrahydrobiopterinIsolectins I-A and I-B of Griffonia (Bandeiraea) simplicifolia. Crystal structure of metal-free GS I-B(4) and molecular basis for metal binding and monosaccharide specificityStructural Basis for Broad Substrate Specificity in Higher Plant beta-D-Glucan GlucohydrolasesKnowledge-Based Protein ModelingSupracrystallographic resolution of interactions contributing to enzyme catalysis by use of natural structural variants and reactivity-probe kineticsIn silico determination and validation of baumannii acinetobactin utilization a structure and ligand binding site.Three-dimensional models of non-NMDA glutamate receptorsCODA: a combined algorithm for predicting the structurally variable regions of protein models.Computational methods in drug discovery.Toward a better understanding of the basis of the molecular mimicry of polysaccharide antigens by peptides: the example of Shigella flexneri 5a.Structure-function relationships in the cysteine proteinases actinidin, papain and papaya proteinase omega. Three-dimensional structure of papaya proteinase omega deduced by knowledge-based modelling and active-centre characteristics determined by tMapping the genetic determinants of pathogenicity and plaque phenotype in swine vesicular disease virusStructural and molecular basis of interaction of HCV non-structural protein 5A with human casein kinase 1α and PKR.Structure of the low-affinity penicillin-binding protein 5 PBP5fm in wild-type and highly penicillin-resistant strains of Enterococcus faeciumCharacterization of a pseudomonad 2-nitrobenzoate nitroreductase and its catabolic pathway-associated 2-hydroxylaminobenzoate mutase and a chemoreceptor involved in 2-nitrobenzoate chemotaxis.Comparison of conformational characteristics in structurally similar protein pairs.Conformational analysis and clustering of short and medium size loops connecting regular secondary structures: a database for modeling and prediction.Analysis of interactive packing of secondary structural elements in alpha/beta units in proteinsStructural biology and bioinformatics in drug design: opportunities and challenges for target identification and lead discovery.Molecular evolution and domain structure of plasminogen-related growth factors (HGF/SF and HGF1/MSP)A novel, small endoglucanase gene, egl5, from Trichoderma reesei isolated by expression in yeast.Chloroplastic aspartate aminotransferase from Arabidopsis thaliana: an examination of the relationship between the structure of the gene and the spatial structure of the protein.A single aspartate residue is involved in both intrinsic gating and blockage by Mg2+ of the inward rectifier, IRK1.A structural model for sequence-specific proflavin-DNA interactions during in vitro frameshift mutagenesis.Modelling the carbohydrate recognition domain of human E-selectin.Modelling, synthesis and biological activity of a BLV proteinase, made of (only) 116 amino acids.The propeptide of cruzipain--a potent selective inhibitor of the trypanosomal enzymes cruzipain and brucipain, and of the human enzyme cathepsin F.The interleukin 1 (IL-1) receptor accessory protein Toll/IL-1 receptor domain: analysis of putative interaction sites in vitro mutagenesis and molecular modeling.Domainal organization of the lower eukaryotic homologs of the yeast RNA polymerase II core subunit Rpb7 reflects functional conservationCharacterization of two distinct MHC class II binding sites in the superantigen staphylococcal enterotoxin A.Catching a common fold.Structure of chymopapain M the late-eluted chymopapain deduced by comparative modelling techniques and active-centre characteristics determined by pH-dependent kinetics of catalysis and reactions with time-dependent inhibitors: the Cys-25/His-159 ioHeterologously expressed inner lipoyl domain of dihydrolipoyl acetyltransferase inhibits ATP-dependent inactivation of pyruvate dehydrogenase complex. Identification of important amino acid residues.Modeling studies of the change in conformation required for cleavage of limited proteolytic sites
P2860
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P2860
18th Sir Hans Krebs lecture. Knowledge-based protein modelling and design.
description
1988 nî lūn-bûn
@nan
1988年の論文
@ja
1988年論文
@yue
1988年論文
@zh-hant
1988年論文
@zh-hk
1988年論文
@zh-mo
1988年論文
@zh-tw
1988年论文
@wuu
1988年论文
@zh
1988年论文
@zh-cn
name
18th Sir Hans Krebs lecture. Knowledge-based protein modelling and design.
@en
18th Sir Hans Krebs lecture. Knowledge-based protein modelling and design.
@nl
type
label
18th Sir Hans Krebs lecture. Knowledge-based protein modelling and design.
@en
18th Sir Hans Krebs lecture. Knowledge-based protein modelling and design.
@nl
prefLabel
18th Sir Hans Krebs lecture. Knowledge-based protein modelling and design.
@en
18th Sir Hans Krebs lecture. Knowledge-based protein modelling and design.
@nl
P2093
P50
P1433
P1476
18th Sir Hans Krebs lecture. Knowledge-based protein modelling and design.
@en
P2093
P304
P356
10.1111/J.1432-1033.1988.TB13917.X
P407
P577
1988-03-01T00:00:00Z