TRAIL-induced apoptosis is preferentially mediated via TRAIL receptor 1 in pancreatic carcinoma cells and profoundly enhanced by XIAP inhibitors.
about
Mesenchymal stem cells as vectors for lung cancer therapyMarine Drugs Regulating Apoptosis Induced by Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand (TRAIL)Small-molecule SMAC mimetics as new cancer therapeuticsTRAIL mutant membrane penetrating peptide alike-MuR6-TR enhances the antitumor effects of TRAIL in pancreatic carcinoma both in vitro and in vivo.F-box protein 10, an NF-κB-dependent anti-apoptotic protein, regulates TRAIL-induced apoptosis through modulating c-Fos/c-FLIP pathwayLoss of TRAIL-receptors is a recurrent feature in pancreatic cancer and determines the prognosis of patients with no nodal metastasis after surgery.TRAIL-receptor preferences in pancreatic cancer cells revisited: Both TRAIL-R1 and TRAIL-R2 have a licence to kill.DR4 specific TRAIL variants are more efficacious than wild-type TRAIL in pancreatic cancer.Immunoglobulin-like transcript receptors on human dermal CD14+ dendritic cells act as a CD8-antagonist to control cytotoxic T cell primingDelivery of sTRAIL variants by MSCs in combination with cytotoxic drug treatment leads to p53-independent enhanced antitumor effectsIAP antagonists sensitize murine osteosarcoma cells to killing by TNFαPotential application of temozolomide in mesenchymal stem cell-based TRAIL gene therapy against malignant gliomaTRAIL receptor gene editing unveils TRAIL-R1 as a master player of apoptosis induced by TRAIL and ER stress.Combined modality therapy with TRAIL or agonistic death receptor antibodies.Death receptors as targets in cancerDifferential activity of GSK-3 isoforms regulates NF-κB and TRAIL- or TNFα induced apoptosis in pancreatic cancer cellsCD70-restricted specific activation of TRAILR1 or TRAILR2 using scFv-targeted TRAIL mutants.TRAIL-NP hybrids for cancer therapy: a review.RIP1 is required for IAP inhibitor-mediated sensitization for TRAIL-induced apoptosis via a RIP1/FADD/caspase-8 cell death complex.TRAIL-engineered pancreas-derived mesenchymal stem cells: characterization and cytotoxic effects on pancreatic cancer cells.Requirement of nuclear factor κB for Smac mimetic-mediated sensitization of pancreatic carcinoma cells for gemcitabine-induced apoptosis.RIP1 protein-dependent assembly of a cytosolic cell death complex is required for inhibitor of apoptosis (IAP) inhibitor-mediated sensitization to lexatumumab-induced apoptosis.LPS promotes resistance to TRAIL-induced apoptosis in pancreatic cancerThe role of apoptosis in the pathology of pancreatic cancerA Novel Fully Human Agonistic Single Chain Fragment Variable Antibody Targeting Death Receptor 5 with Potent Antitumor Activity In Vitro and In Vivo.Should We Keep Walking along the Trail for Pancreatic Cancer Treatment? Revisiting TNF-Related Apoptosis-Inducing Ligand for Anticancer Therapy.
P2860
Q26853498-4C191F5F-081C-49AB-B02A-F6AAF43ACABFQ26859211-475DD5FF-2FD2-48DE-8F32-0620AF66D102Q26864204-C9F02161-1735-40F3-9E1E-F73D342E6A5CQ33674881-B79F9018-540E-40F9-947D-6A318AB35DBAQ34160097-F1069A91-2304-41F0-A75D-DF92C826B75BQ34608366-B4319F94-A7A8-4C75-995A-5D8C3BDF425CQ35681794-3CD6B4AA-CCCA-4278-B06E-64FC49B3DC6DQ36215003-8250CF3B-BAE8-4E7B-B07E-6113EEF0A352Q36414778-B1C45AAD-9F7B-43F5-B3BA-12A4C177C548Q37073589-CFEA603F-A67B-42E6-A08A-9695A40CE875Q37376164-A665A3EE-7FA4-492D-AEAD-95BAD503C944Q37585453-AE9B6627-AF0C-4EF8-BEF3-5C48F2228264Q37706093-FA30BE0D-A356-4C6B-B291-A60CD120CD8BQ37832083-AF0B8C16-9E4E-40A7-AFCC-0C719535BEACQ38103591-6288BD68-8D4E-4F4B-8BC7-C33B63840D4CQ39011040-93BF51B7-95FD-47AF-8811-AFE24508C786Q39028796-B1EE82B8-2A5D-4EBB-8BE5-BDCE8EEF2705Q39263297-E87A249D-DF66-4A71-B18B-B94DDB475BC8Q39298005-C25206DD-CA4B-4354-981B-153BD2663A91Q39319003-20F1D32E-F83C-4450-A448-449539104A7AQ39412878-7A8A7F68-7B45-48FA-AC80-CBB578458DD3Q41311490-B86B510D-DC26-47BE-9779-46A7B3B943BAQ41949682-E4A3770A-A9CD-4EFD-9DDE-3AB4ADF0F6F8Q42212254-76B9887C-7F4F-42BB-93C3-9C50AD48291AQ45903630-4024EFD8-E61F-4E87-B509-D1785B7AA843Q51760860-D4516A91-AD70-44A0-9CBF-1C0DF81E1036
P2860
TRAIL-induced apoptosis is preferentially mediated via TRAIL receptor 1 in pancreatic carcinoma cells and profoundly enhanced by XIAP inhibitors.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
TRAIL-induced apoptosis is pre ...... y enhanced by XIAP inhibitors.
@en
TRAIL-induced apoptosis is pre ...... y enhanced by XIAP inhibitors.
@nl
type
label
TRAIL-induced apoptosis is pre ...... y enhanced by XIAP inhibitors.
@en
TRAIL-induced apoptosis is pre ...... y enhanced by XIAP inhibitors.
@nl
prefLabel
TRAIL-induced apoptosis is pre ...... y enhanced by XIAP inhibitors.
@en
TRAIL-induced apoptosis is pre ...... y enhanced by XIAP inhibitors.
@nl
P2093
P50
P1476
TRAIL-induced apoptosis is pre ...... y enhanced by XIAP inhibitors.
@en
P2093
Caroline Ref
Dominic Stadel
Gerry Cohen
Marion MacFarlane
Max Bachem
Peter Möller
Robin Humphreys
Shaoxia Zhou
P304
P356
10.1158/1078-0432.CCR-10-0985
P407
P577
2010-10-12T00:00:00Z