CD40 and LMP-1 both signal from lipid rafts but LMP-1 assembles a distinct, more efficient signaling complex.
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PRA1 promotes the intracellular trafficking and NF-kappaB signaling of EBV latent membrane protein 1BS69, a specific adaptor in the latent membrane protein 1-mediated c-Jun N-terminal kinase pathwayProteome-wide dysregulation by PRA1 depletion delineates a role of PRA1 in lipid transport and cell migrationLipid rafts and B cell signalingEBNA-1, a bifunctional transcriptional activatorTRAF6 is a critical mediator of signal transduction by the viral oncogene latent membrane protein 1Two carboxyl-terminal activation regions of Epstein-Barr virus latent membrane protein 1 activate NF-kappaB through distinct signaling pathways in fibroblast cell linesLipid rafts and B-cell activation.In nasopharyngeal carcinoma cells, Epstein-Barr virus LMP1 interacts with galectin 9 in membrane raft elements resistant to simvastatin.Epstein-Barr virus-encoded LMP1 interacts with FGD4 to activate Cdc42 and thereby promote migration of nasopharyngeal carcinoma cells.The germinal center kinase TNIK is required for canonical NF-κB and JNK signaling in B-cells by the EBV oncoprotein LMP1 and the CD40 receptor.Repositioning antimicrobial agent pentamidine as a disruptor of the lateral interactions of transmembrane domain 5 of EBV latent membrane protein 1.LMP1 association with CD63 in endosomes and secretion via exosomes limits constitutive NF-κB activationTransmembrane peptides used to investigate the homo-oligomeric interface and binding hotspot of latent membrane protein 1.Multi-Tox: application of the ToxR-transcriptional reporter assay to the study of multi-pass protein transmembrane domain oligomerizationHMG CoA reductase inhibitors (statins) to treat Epstein-Barr virus-driven lymphomaThe viral oncoprotein LMP1 exploits TRADD for signaling by masking its apoptotic activity.Regulation of the subcellular localization of tumor necrosis factor receptor-associated factor (TRAF)2 by TRAF1 reveals mechanisms of TRAF2 signalingSimvastatin induces apoptosis of Epstein-Barr virus (EBV)-transformed lymphoblastoid cell lines and delays development of EBV lymphomas.High molecular weight complex analysis of Epstein-Barr virus Latent Membrane Protein 1 (LMP-1): structural insights into LMP-1's homo-oligomerization and lipid raft associationRoles for TNF-receptor associated factor 3 (TRAF3) in lymphocyte functions.Characterization of the latent membrane protein 1 signaling complex of Epstein-Barr virus in the membrane of mammalian cells with bimolecular fluorescence complementation.Effects of Epstein-Barr virus infection on the development of multiple myeloma after liver transplantation.LMP-1's transmembrane domains encode multiple functions required for LMP-1's efficient signaling.Two retroviral entry pathways distinguished by lipid raft association of the viral receptor and differences in viral infectivity.Transmembrane domains 1 and 2 of the latent membrane protein 1 of Epstein-Barr virus contain a lipid raft targeting signal and play a critical role in cytostasis.The B subunit of Escherichia coli heat-labile enterotoxin enhances CD8+ cytotoxic-T-lymphocyte killing of Epstein-Barr virus-infected cell lines.LMP1, a viral relative of the TNF receptor family, signals principally from intracellular compartments.A membrane leucine heptad contributes to trafficking, signaling, and transformation by latent membrane protein 1.Location of major histocompatibility complex class II molecules in rafts on dendritic cells enhances the efficiency of T-cell activation and proliferation.Pre-assembly of the extracellular domains of CD40 is not necessary for rescue of mouse B cells from anti-immunoglobulin M-induced apoptosis.The receptor-bound N-terminal ectodomain of the amyloid precursor protein is associated with membrane rafts.Negative regulation of Epstein-Barr virus latent membrane protein 1-mediated functions by the bone morphogenetic protein receptor IA-binding protein, BRAM1.Cytoplasmic aggregation of TRAF2 and TRAF5 proteins in the Hodgkin-Reed-Sternberg cellsEpstein-Barr virus transforming protein LMP1 plays a critical role in virus production.Canonical NF-kappaB activation is essential for Epstein-Barr virus latent membrane protein 1 TES2/CTAR2 gene regulation.Re-engineered CD40 receptor enables potent pharmacological activation of dendritic-cell cancer vaccines in vivo.CADM1 is essential for KSHV-encoded vGPCR-and vFLIP-mediated chronic NF-κB activation.Transmembrane Domains Mediate Intra- and Extracellular Trafficking of Epstein-Barr Virus Latent Membrane Protein 1The transmembranous domain of CD40 determines CD40 partitioning into lipid rafts
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P2860
CD40 and LMP-1 both signal from lipid rafts but LMP-1 assembles a distinct, more efficient signaling complex.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
2001年论文
@zh
2001年论文
@zh-cn
name
CD40 and LMP-1 both signal fro ...... e efficient signaling complex.
@en
CD40 and LMP-1 both signal fro ...... e efficient signaling complex.
@nl
type
label
CD40 and LMP-1 both signal fro ...... e efficient signaling complex.
@en
CD40 and LMP-1 both signal fro ...... e efficient signaling complex.
@nl
prefLabel
CD40 and LMP-1 both signal fro ...... e efficient signaling complex.
@en
CD40 and LMP-1 both signal fro ...... e efficient signaling complex.
@nl
P2860
P356
P1433
P1476
CD40 and LMP-1 both signal fro ...... e efficient signaling complex.
@en
P2093
P2860
P304
P356
10.1093/EMBOJ/20.11.2641
P407
P577
2001-06-01T00:00:00Z