A thermally responsive biopolymer conjugated to an acid-sensitive derivative of paclitaxel stabilizes microtubules, arrests cell cycle, and induces apoptosis.
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The Prodrug Approach: A Successful Tool for Improving Drug SolubilityThe design and delivery of a thermally responsive peptide to inhibit S100B-mediated neurodegenerationCell penetrating peptides fused to a thermally targeted biopolymer drug carrier improve the delivery and antitumor efficacy of an acid-sensitive doxorubicin derivativeFusion of cell-penetrating peptides to thermally responsive biopolymer improves tumor accumulation of p21 peptide in a mouse model of pancreatic cancer.A polypeptide drug carrier for maternal delivery and prevention of fetal exposure.Thermal targeting of an acid-sensitive doxorubicin conjugate of elastin-like polypeptide enhances the therapeutic efficacy compared with the parent compound in vivo.Anticancer activity of proapoptotic peptides is highly improved by thermal targeting using elastin-like polypeptides.Structural and hydrodynamic analysis of a novel drug delivery vector: ELP[V5G3A2-150].Paclitaxel drug delivery systems.Designing protein-based biomaterials for medical applications.Applications of elastin-like polypeptides in drug delivery.Elastin-like polypeptide for improved drug delivery for anticancer therapy: preclinical studies and future applications.Smart linkers in polymer-drug conjugates for tumor-targeted delivery.A kidney-selective biopolymer for targeted drug delivery.Designing Smart Materials with Recombinant Proteins.Synergistic inhibition of colon cancer cell growth with nanoemulsion-loaded paclitaxel and PI3K/mTOR dual inhibitor BEZ235 through apoptosis.Noncovalent interaction-assisted drug delivery system with highly efficient uptake and release of paclitaxel for anticancer therapy.The design and delivery of a PKA inhibitory polypeptide to treat SCA1.Preclinical development of drug delivery systems for paclitaxel-based cancer chemotherapy.Self-Assembly of Thermoresponsive Recombinant Silk-Elastinlike Nanogels.Integrin-targeted nano-sized polymeric systems for paclitaxel conjugation: a comparative study.Effects of cell penetrating Notch inhibitory peptide conjugated to elastin-like polypeptide on glioblastoma cells.A Maternally Sequestered, Biopolymer‐Stabilized Vascular Endothelial Growth Factor (VEGF) Chimera for Treatment of Preeclampsia.Preparation and characterization of elastin-like polypeptide scaffolds for local delivery of antibiotics and proteins.Molecular Size Modulates Pharmacokinetics, Biodistribution, and Renal Deposition of the Drug Delivery Biopolymer Elastin-like Polypeptide.
P2860
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P2860
A thermally responsive biopolymer conjugated to an acid-sensitive derivative of paclitaxel stabilizes microtubules, arrests cell cycle, and induces apoptosis.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
A thermally responsive biopoly ...... cycle, and induces apoptosis.
@en
A thermally responsive biopoly ...... cycle, and induces apoptosis.
@nl
type
label
A thermally responsive biopoly ...... cycle, and induces apoptosis.
@en
A thermally responsive biopoly ...... cycle, and induces apoptosis.
@nl
prefLabel
A thermally responsive biopoly ...... cycle, and induces apoptosis.
@en
A thermally responsive biopoly ...... cycle, and induces apoptosis.
@nl
P2093
P2860
P1476
A thermally responsive biopoly ...... cycle, and induces apoptosis.
@en
P2093
Claudia Ryppa
Drazen Raucher
Felix Kratz
Shama Moktan
P2860
P2888
P304
P356
10.1007/S10637-010-9560-X
P577
2010-10-12T00:00:00Z