Regulation of nuclear poly(A) addition controls the expression of immunoglobulin M secretory mRNA.
about
3' end mRNA processing: molecular mechanisms and implications for health and diseaseRegulation of poly(A) polymerase by 14-3-3epsilonProcessing and transcriptome expansion at the mRNA 3' end in health and disease: finding the right endERK is a novel regulatory kinase for poly(A) polymeraseRadiation leukemia virus common integration at the Kis2 locus: simultaneous overexpression of a novel noncoding RNA and of the proximal Phf6 geneZfp318 regulates IgD expression by abrogating transcription termination within the Ighm/Ighd locusB-cell and plasma-cell splicing differences: a potential role in regulated immunoglobulin RNA processing.Non-snRNP U1A levels decrease during mammalian B-cell differentiation and release the IgM secretory poly(A) site from repressionAlternative polyadenylation of adeno-associated virus type 5 RNA within an internal intron is governed by both a downstream element within the intron 3' splice acceptor and an element upstream of the P41 initiation site.Determinants within an 18-amino-acid U1A autoregulatory domain that uncouple cooperative RNA binding, inhibition of polyadenylation, and homodimerization.Multiple features contribute to the use of the immunoglobulin M secretion-specific poly(A) signal but are not required for developmental regulation.Implications of polyadenylation in health and disease.Phylogenetic analysis of mRNA polyadenylation sites reveals a role of transposable elements in evolution of the 3'-end of genesU1 snRNP-Dependent Suppression of Polyadenylation: Physiological Role and Therapeutic Opportunities in Cancer.Alternative polyadenylation signals in the 3' non-coding region of a voltage-gated potassium channel gene are major determinants of mRNA isoform expression.U1A regulates 3' processing of the survival motor neuron mRNA.Knock-down of 25 kDa subunit of cleavage factor Im in Hela cells alters alternative polyadenylation within 3'-UTRs.A bipartite U1 site represses U1A expression by synergizing with PIE to inhibit nuclear polyadenylation.Alternative polyadenylation of adeno-associated virus type 5 RNA within an internal intron is governed by the distance between the promoter and the intron and is inhibited by U1 small nuclear RNP binding to the intervening donor.U1A inhibits cleavage at the immunoglobulin M heavy-chain secretory poly(A) site by binding between the two downstream GU-rich regions.The role of RNA structure in the interaction of U1A protein with U1 hairpin II RNADistance-dependent processing of adeno-associated virus type 5 RNA is controlled by 5' exon definition.Induced HMGA1a expression causes aberrant splicing of Presenilin-2 pre-mRNA in sporadic Alzheimer's disease.CFIm25 inhibits hepatocellular carcinoma metastasis by suppressing the p38 and JNK/c-Jun signaling pathways.Sequences adjacent to the 5' splice site control U1A binding upstream of the IgM heavy chain secretory poly(A) site.
P2860
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P2860
Regulation of nuclear poly(A) addition controls the expression of immunoglobulin M secretory mRNA.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
2001年论文
@zh
2001年论文
@zh-cn
name
Regulation of nuclear poly
@nl
Regulation of nuclear poly(A) ...... munoglobulin M secretory mRNA.
@en
type
label
Regulation of nuclear poly
@nl
Regulation of nuclear poly(A) ...... munoglobulin M secretory mRNA.
@en
prefLabel
Regulation of nuclear poly
@nl
Regulation of nuclear poly(A) ...... munoglobulin M secretory mRNA.
@en
P2093
P2860
P356
P1433
P1476
Regulation of nuclear poly(A) ...... munoglobulin M secretory mRNA.
@en
P2093
P2860
P304
P356
10.1093/EMBOJ/20.22.6443
P407
P577
2001-11-01T00:00:00Z