Protein phosphatase 2A negatively regulates integrin alpha(IIb)beta(3) signaling. - Wikidata - awgldk - TriplyDB

Protein phosphatase 2A negatively regulates integrin alpha(IIb)beta(3) signaling.

Protein phosphatase 2A negatively regulates integrin alpha(IIb)beta(3) signaling.

http://www.wikidata.org/entity/Q39647592

about

Platelet signaling: a complex interplay between inhibitory and activatory networks Integrin cytoplasmic tail interactions The catalytic subunit of protein phosphatase 1 gamma regulates thrombin-induced murine platelet alpha(IIb)beta(3) function.Cross-talk between serine/threonine protein phosphatase 2A and protein tyrosine phosphatase 1B regulates Src activation and adhesion of integrin αIIbβ3 to fibrinogen.Transmembrane and Juxtamembrane Structure of αL Integrin in Bicelles.Differential dephosphorylation of the protein kinase C-zeta (PKCζ) in an integrin αIIbβ3-dependent manner in platelets Prioritizing genetic variants for causality on the basis of preferential linkage disequilibrium.Two distinct roles of mitogen-activated protein kinases in platelets and a novel Rac1-MAPK-dependent integrin outside-in retractile signaling pathway Regulation of integrin activity and signalling A Novel Interaction of the Catalytic Subunit of Protein Phosphatase 2A with the Adaptor Protein CIN85 Suppresses Phosphatase Activity and Facilitates Platelet Outside-in αIIbβ3 Integrin Signaling.A receptor-interacting protein 1 (RIP1)-independent necrotic death under the control of protein phosphatase PP2A that involves the reorganization of actin cytoskeleton and the action of cofilin-1.Mechanism of activation and functional role of protein kinase Ceta in human platelets.The heterotrimeric G protein Gβ1 interacts with the catalytic subunit of protein phosphatase 1 and modulates G protein-coupled receptor signaling in platelets.Negative regulators of platelet activation and adhesion.

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P2860

Protein phosphatase 2A negatively regulates integrin alpha(IIb)beta(3) signaling.

http://www.wikidata.org/entity/Q39647592

description

2008 nî lūn-bûn

@nan

2008年の論文

@ja

2008年論文

@yue

2008年論文

@zh-hant

2008年論文

@zh-hk

2008年論文

@zh-mo

2008年論文

@zh-tw

2008年论文

@wuu

2008年论文

@zh

2008年论文

@zh-cn

name

Protein phosphatase 2A negatively regulates integrin alpha

@nl

Protein phosphatase 2A negatively regulates integrin alpha(IIb)beta(3) signaling.

@en

type

label

Protein phosphatase 2A negatively regulates integrin alpha

@nl

Protein phosphatase 2A negatively regulates integrin alpha(IIb)beta(3) signaling.

@en

prefLabel

Protein phosphatase 2A negatively regulates integrin alpha

@nl

Protein phosphatase 2A negatively regulates integrin alpha(IIb)beta(3) signaling.

@en

P1433

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P1433

Journal of Biological Chemistry

P1476

Protein phosphatase 2A negatively regulates integrin alpha(IIb)beta(3) signaling.

@en

P2093

Angela L Bergeron

http://www.w3.org/2001/XMLSchema#string

Francisca C Gushiken

http://www.w3.org/2001/XMLSchema#string

K Vinod Vijayan

http://www.w3.org/2001/XMLSchema#string

Subhashree Pradhan

http://www.w3.org/2001/XMLSchema#string

Vimal Patel

http://www.w3.org/2001/XMLSchema#string

Yan Liu

http://www.w3.org/2001/XMLSchema#string

Yuandong Peng

http://www.w3.org/2001/XMLSchema#string

P2860

Integrin alpha 2 beta 1 promotes activation of protein phosphatase 2A and dephosphorylation of Akt and glycogen synthase kinase 3 beta.

Coordinate interactions of Csk, Src, and Syk kinases with [alpha]IIb[beta]3 initiate integrin signaling to the cytoskeleton

PTP-1B is an essential positive regulator of platelet integrin signaling

Protein phosphatase 2A: a highly regulated family of serine/threonine phosphatases implicated in cell growth and signalling

RACK1 targets the extracellular signal-regulated kinase/mitogen-activated protein kinase pathway to link integrin engagement with focal adhesion disassembly and cell motility

Sequential activation of p38 and ERK pathways by cGMP-dependent protein kinase leading to activation of the platelet integrin alphaIIb beta3

Association of CIB with GPIIb/IIIa during outside-in signaling is required for platelet spreading on fibrinogen

Molecular basis of CIB binding to the integrin alpha IIb cytoplasmic domain

ICln, a novel integrin alphaIIbbeta3-associated protein, functionally regulates platelet activation

Integrins: dynamic scaffolds for adhesion and signaling in platelets

P304

12862-12869

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scholarly article

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10.1074/JBC.M708804200

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P433

19

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283

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2008-03-11T00:00:00Z

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18334487

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2442329

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