The protein import motor of mitochondria: a targeted molecular ratchet driving unfolding and translocation.
about
Organization and function of the small Tim complexes acting along the import pathway of metabolite carriers into mammalian mitochondriaMultiple pathways for sorting mitochondrial precursor proteinsThe J domain-related cochaperone Tim16 is a constituent of the mitochondrial TIM23 preprotein translocase.Importing mitochondrial proteins: machineries and mechanismsTargeting and assembly of components of the TOC protein import complex at the chloroplast outer envelope membrane.Comparison of the protein-unfolding pathways between mitochondrial protein import and atomic-force microscopy measurements.Pulling geometry defines the mechanical resistance of a beta-sheet protein.Ligand binding modulates the mechanical stability of dihydrofolate reductase.Convergent evolution of heat-inducibility during subfunctionalization of the Hsp70 gene family.Hsp70 chaperones accelerate protein translocation and the unfolding of stable protein aggregates by entropic pulling.Signal anchor sequence provides motive force for polypeptide chain translocation through the endoplasmic reticulum membrane.Forespore engulfment mediated by a ratchet-like mechanism.BimS-induced apoptosis requires mitochondrial localization but not interaction with anti-apoptotic Bcl-2 proteins.Reconstructing the mitochondrial protein import machinery of Chlamydomonas reinhardtii.Mge1, a nucleotide exchange factor of Hsp70, acts as an oxidative sensor to regulate mitochondrial Hsp70 function.Pushing, pulling and trapping--modes of motor protein supported protein translocation.Multiple pathways for mitochondrial protein traffic.Protein import into chloroplasts: dealing with the (membrane) integration problem.Import of ribosomal proteins into yeast mitochondria.Role of membrane contact sites in protein import into mitochondria.Functional Diversity of Human Mitochondrial J-proteins Is Independent of Their Association with the Inner Membrane Presequence Translocase.Interactions of mitochondrial presequence peptides with the mitochondrial outer membrane preprotein translocase TOM.Mitochondrial targeting of the Arabidopsis F1-ATPase γ-subunit via multiple compensatory and synergistic presequence motifs.Folding of fumarase during mitochondrial import determines its dual targeting in yeast.A Brownian ratchet for protein translocation including dissociation of ratcheting sites.The most C-terminal tri-glycine segment within the polyglycine stretch of the pea Toc75 transit peptide plays a critical role for targeting the protein to the chloroplast outer envelope membrane.A mitochondrial ratchet.Protein Translocation into the Intermembrane Space and Matrix of Mitochondria: Mechanisms and Driving Forces.Tom70 enhances mitochondrial preprotein import efficiency by binding to internal targeting sequences.Hsp70 chaperones use ATP to remodel native protein oligomers and stable aggregates by entropic pulling.Impaired interdomain communication in mitochondrial Hsp70 results in the loss of inward-directed translocation force.Response to the Comment by Ainavarapu et al.
P2860
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P2860
The protein import motor of mitochondria: a targeted molecular ratchet driving unfolding and translocation.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
2002年论文
@zh
2002年论文
@zh-cn
name
The protein import motor of mi ...... g unfolding and translocation.
@en
The protein import motor of mi ...... g unfolding and translocation.
@nl
type
label
The protein import motor of mi ...... g unfolding and translocation.
@en
The protein import motor of mi ...... g unfolding and translocation.
@nl
prefLabel
The protein import motor of mi ...... g unfolding and translocation.
@en
The protein import motor of mi ...... g unfolding and translocation.
@nl
P2093
P2860
P356
P1433
P1476
The protein import motor of mi ...... g unfolding and translocation.
@en
P2093
Achim Brinker
Ismail Moarefi
Koji Okamoto
Michael Brunner
Stefan A Paschen
Walter Neupert
P2860
P304
P356
10.1093/EMBOJ/CDF358
P407
P577
2002-07-01T00:00:00Z