A sensitive, simple assay of mitochondrial ATP synthesis of cultured mammalian cells suitable for high-throughput analysis.
about
Evaluation of intramitochondrial ATP levels identifies G0/G1 switch gene 2 as a positive regulator of oxidative phosphorylation.Higd1a is a positive regulator of cytochrome c oxidase.Knockdown of DAPIT (diabetes-associated protein in insulin-sensitive tissue) results in loss of ATP synthase in mitochondria.Turnover of ATP synthase subunits in F1-depleted HeLa and yeast cells.Tumor cells switch to mitochondrial oxidative phosphorylation under radiation via mTOR-mediated hexokinase II inhibition--a Warburg-reversing effectIdentification of small molecules that improve ATP synthesis defects conferred by Leber's hereditary optic neuropathy mutationsEvaluation of genes involved in oxidative phosphorylation in yeast by developing a simple and rapid method to measure mitochondrial ATP synthetic activity.Assessing actual contribution of IF1, inhibitor of mitochondrial FoF1, to ATP homeostasis, cell growth, mitochondrial morphology, and cell viability.Screening of protein kinase inhibitors and knockdown experiments identified four kinases that affect mitochondrial ATP synthesis activity.General anesthetics cause mitochondrial dysfunction and reduction of intracellular ATP levels.Methods to detect apoptotic cell death.Modeling of Friedreich ataxia-related iron overloading cardiomyopathy using patient-specific-induced pluripotent stem cells.Assembly of human mitochondrial ATP synthase through two separate intermediates, F1-c-ring and b-e-g complex.Population of ATP synthase molecules in mitochondria is limited by available 6.8-kDa proteolipid protein (MLQ).
P2860
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P2860
A sensitive, simple assay of mitochondrial ATP synthesis of cultured mammalian cells suitable for high-throughput analysis.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
A sensitive, simple assay of m ...... for high-throughput analysis.
@en
A sensitive, simple assay of m ...... for high-throughput analysis.
@nl
type
label
A sensitive, simple assay of m ...... for high-throughput analysis.
@en
A sensitive, simple assay of m ...... for high-throughput analysis.
@nl
prefLabel
A sensitive, simple assay of m ...... for high-throughput analysis.
@en
A sensitive, simple assay of m ...... for high-throughput analysis.
@nl
P1476
A sensitive, simple assay of m ...... for high-throughput analysis.
@en
P2093
Makoto Fujikawa
Masasuke Yoshida
P304
P356
10.1016/J.BBRC.2010.09.089
P407
P577
2010-09-26T00:00:00Z