Proteolysis of CD14 on human gingival fibroblasts by arginine-specific cysteine proteinases from Porphyromonas gingivalis leading to down-regulation of lipopolysaccharide-induced interleukin-8 production.
about
Porphyromonas gingivalis gingipains cause defective macrophage migration towards apoptotic cells and inhibit phagocytosis of primary apoptotic neutrophils.Identification of a gingipain-sensitive surface ligand of Porphyromonas gingivalis that induces Toll-like receptor 2- and 4-independent NF-kappaB activation in CHO cells.Inactivation of membrane tumor necrosis factor alpha by gingipains from Porphyromonas gingivalis.Dichotomy of gingipains action as virulence factors: from cleaving substrates with the precision of a surgeon's knife to a meat chopper-like brutal degradation of proteins.Lysine-specific gingipain promotes lipopolysaccharide- and active-vitamin D3-induced osteoclast differentiation by degrading osteoprotegerinPorphyromonas gingivalis lipopolysaccharide antagonizes Escherichia coli lipopolysaccharide at toll-like receptor 4 in human endothelial cells.Corruption of innate immunity by bacterial proteases.Porphyromonas gingivalis gingipains selectively reduce CD14 expression, leading to macrophage hyporesponsiveness to bacterial infection.Antigens of bacteria associated with periodontitis.Porphyromonas gingivalis, Treponema denticola, and Tannerella forsythia: the "red complex", a prototype polybacterial pathogenic consortium in periodontitis.Generation of inflammatory stimuli: how bacteria set up inflammatory responses in the gingiva.Cleavage of CD14 and LBP by a protease from Prevotella intermediaKinin danger signals proteolytically released by gingipain induce Fimbriae-specific IFN-gamma- and IL-17-producing T cells in mice infected intramucosally with Porphyromonas gingivalis.The gingipains: scissors and glue of the periodontal pathogen, Porphyromonas gingivalis.Periodontitis as a risk factor of atherosclerosis.Discrete proteolysis of focal contact and adherens junction components in Porphyromonas gingivalis-infected oral keratinocytes: a strategy for cell adhesion and migration disabling.Gingipains from Porphyromonas gingivalis synergistically induce the production of proinflammatory cytokines through protease-activated receptors with Toll-like receptor and NOD1/2 ligands in human monocytic cells.Gingipains inactivate a cell surface ligand on Porphyromonas gingivalis that induces TLR2-and TLR4-independent signaling.In vitro models of tissue penetration and destruction by Porphyromonas gingivalis.Differential effects of periopathogens on host protease inhibitors SLPI, elafin, SCCA1, and SCCA2.Virulence factors of Porphyromonas gingivalis are modified by polyphenol oxidase and asparaginase.The periodontal war: microbes and immunity.DX-9065a inhibits proinflammatory events induced by gingipains and factor Xa.Quantitative real-time polymerase chain reaction based on single copy gene sequence for detection of periodontal pathogens.
P2860
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P2860
Proteolysis of CD14 on human gingival fibroblasts by arginine-specific cysteine proteinases from Porphyromonas gingivalis leading to down-regulation of lipopolysaccharide-induced interleukin-8 production.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
2002年论文
@zh
2002年论文
@zh-cn
name
Proteolysis of CD14 on human g ...... uced interleukin-8 production.
@en
Proteolysis of CD14 on human g ...... uced interleukin-8 production.
@nl
type
label
Proteolysis of CD14 on human g ...... uced interleukin-8 production.
@en
Proteolysis of CD14 on human g ...... uced interleukin-8 production.
@nl
prefLabel
Proteolysis of CD14 on human g ...... uced interleukin-8 production.
@en
Proteolysis of CD14 on human g ...... uced interleukin-8 production.
@nl
P2093
P2860
P921
P1476
Proteolysis of CD14 on human g ...... uced interleukin-8 production.
@en
P2093
Eiji Nemoto
Haruhiko Takada
Hidetoshi Shimauchi
Hiroyuki Tada
James Travis
Nobuhiro Takahashi
Shunji Sugawara
Takahisa Imamura
P2860
P304
P356
10.1128/IAI.70.6.3304-3307.2002
P407
P50
P577
2002-06-01T00:00:00Z