Dynamic chromosomal rearrangements in Hodgkin's lymphoma are due to ongoing three-dimensional nuclear remodeling and breakage-bridge-fusion cycles
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Genomic Instability: The Driving Force behind Refractory/Relapsing Hodgkin's Lymphoma.3D imaging of telomeres and nuclear architecture: An emerging tool of 3D nano-morphology-based diagnosis.Shattered and stitched chromosomes-chromothripsis and chromoanasynthesis-manifestations of a new chromosome crisis?Sister chromatid cohesion defects are associated with chromosome instability in Hodgkin lymphoma cells.LMP1 mediates multinuclearity through downregulation of shelterin proteins and formation of telomeric aggregates.Three-dimensional Telomere Signatures of Hodgkin- and Reed-Sternberg Cells at Diagnosis Identify Patients with Poor Response to Conventional ChemotherapyThree-dimensional Nuclear Telomere Organization in Multiple Myeloma.Mechanisms and clinical applications of chromosomal instability in lymphoid malignancy.Disruption of direct 3D telomere-TRF2 interaction through two molecularly disparate mechanisms is a hallmark of primary Hodgkin and Reed-Sternberg cells.DNA Superresolution Structure of Reed-Sternberg Cells Differs Between Long-Lasting Remission Versus Relapsing Hodgkin's Lymphoma Patients.MYCN overexpression is associated with unbalanced copy number gain, altered nuclear location, and overexpression of chromosome arm 17q genes in neuroblastoma tumors and cell lines.Differences in nuclear DNA organization between lymphocytes, Hodgkin and Reed-Sternberg cells revealed by structured illumination microscopy.LMP1 and Dynamic Progressive Telomere Dysfunction: A Major Culprit in EBV-Associated Hodgkin's Lymphoma.3D nuclear organization of telomeres in the Hodgkin cell lines U-HO1 and U-HO1-PTPN1: PTPN1 expression prevents the formation of very short telomeres including "t-stumps".3D nuclear organization and genomic instability in cancerMitotic errors, aneuploidy and micronuclei in Hodgkin lymphoma pathogenesis.The kelch protein KLHDC8B guards against mitotic errors, centrosomal amplification, and chromosomal instability.Three-dimensional telomere architecture of esophageal squamous cell carcinoma: comparison of tumor and normal epithelial cells.Selected telomere length changes and aberrant three-dimensional nuclear telomere organization during fast-onset mouse plasmacytomas.Distinct and shared three-dimensional chromosome organization patterns in lymphocytes, monoclonal gammopathy of undetermined significance and multiple myeloma.Three-dimensional nuclear telomere architecture changes during endometrial carcinoma development.HIV-1 Tat protein induces DNA damage in human peripheral blood B-lymphocytes via mitochondrial ROS production.The Use of 3D Telomere FISH for the Characterization of the Nuclear Architecture in EBV-Positive Hodgkin's Lymphoma.Chromosomal Instability in Hodgkin Lymphoma: An In-Depth Review and Perspectives.Aurora B kinase in Hodgkin lymphoma: immunohistochemical pattern of expression in neoplastic Hodgkin and Reed-Sternberg cells.Heterozygous mutations in the PALB2 hereditary breast cancer predisposition gene impact on the three-dimensional nuclear organization of patient-derived cell lines.The Role of Immune Checkpoint Inhibitors in Classical Hodgkin Lymphoma.The Transition between Telomerase and ALT Mechanisms in Hodgkin Lymphoma and Its Predictive Value in Clinical Outcomes.Distinct 3D Structural Patterns of Lamin A/C Expression in Hodgkin and Reed-Sternberg CellsIndependent Mechanisms Lead to Genomic Instability in Hodgkin Lymphoma: Microsatellite or Chromosomal Instability
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P2860
Dynamic chromosomal rearrangements in Hodgkin's lymphoma are due to ongoing three-dimensional nuclear remodeling and breakage-bridge-fusion cycles
description
2010 nî lūn-bûn
@nan
2010年の論文
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2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
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2010年论文
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2010年论文
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name
Dynamic chromosomal rearrangem ...... breakage-bridge-fusion cycles
@en
Dynamic chromosomal rearrangem ...... breakage-bridge-fusion cycles.
@nl
type
label
Dynamic chromosomal rearrangem ...... breakage-bridge-fusion cycles
@en
Dynamic chromosomal rearrangem ...... breakage-bridge-fusion cycles.
@nl
prefLabel
Dynamic chromosomal rearrangem ...... breakage-bridge-fusion cycles
@en
Dynamic chromosomal rearrangem ...... breakage-bridge-fusion cycles.
@nl
P2093
P2860
P1433
P1476
Dynamic chromosomal rearrangem ...... breakage-bridge-fusion cycles
@en
P2093
Amanda Guffei
Hans Knecht
Ludger Klewes
Rahul Sarkar
P2860
P304
P356
10.3324/HAEMATOL.2010.030171
P577
2010-09-07T00:00:00Z