Hedgehog signaling maintains chemoresistance in myeloid leukemic cells.
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Aberrant GLI1 Activation in DNA Damage Response, Carcinogenesis and ChemoresistanceHedgehog Signaling in the Maintenance of Cancer Stem CellsMolecular pathways: novel approaches for improved therapeutic targeting of Hedgehog signaling in cancer stem cellsViolacein induces death of resistant leukaemia cells via kinome reprogramming, endoplasmic reticulum stress and Golgi apparatus collapseStemness in Cancer: Stem Cells, Cancer Stem Cells, and Their Microenvironment.Penfluridol suppresses glioblastoma tumor growth by Akt-mediated inhibition of GLI1.Deactivation of signal transducer and activator of transcription 3 reverses chemotherapeutics resistance of leukemia cells via down-regulating P-gpA critical role of autocrine sonic hedgehog signaling in human CD138+ myeloma cell survival and drug resistance.JNK signaling maintains the mesenchymal properties of multi-drug resistant human epidermoid carcinoma KB cells through snail and twist1.ABCG2 is a direct transcriptional target of hedgehog signaling and involved in stroma-induced drug tolerance in diffuse large B-cell lymphoma.Sonic hedgehog produced by bone marrow-derived mesenchymal stromal cells supports cell survival in myelodysplastic syndromeTargeting Hedgehog signaling pathway and autophagy overcomes drug resistance of BCR-ABL-positive chronic myeloid leukemiaHedgehog pathway as a drug target: Smoothened inhibitors in development.CCAAT/enhancer-binding protein δ facilitates bacterial dissemination during pneumococcal pneumonia in a platelet-activating factor receptor-dependent mannerThe Hedgehog pathway: role in cell differentiation, polarity and proliferationNatural paniceins from mediterranean sponge inhibit the multidrug resistance activity of Patched and increase chemotherapy efficiency on melanoma cellsDeregulated hedgehog pathway signaling is inhibited by the smoothened antagonist LDE225 (Sonidegib) in chronic phase chronic myeloid leukaemiaInhibition of the hedgehog pathway targets the tumor-associated stroma in pancreatic cancer.Targeting hedgehog signaling in cancer: research and clinical developments.GPCR-like signaling mediated by smoothened contributes to acquired chemoresistance through activating Gli.Targeting the hedgehog transcription factors GLI1 and GLI2 restores sensitivity to vemurafenib-resistant human melanoma cellsMechanisms of Hedgehog signalling in cancer.Hedgehog signaling pathway and cancer therapeutics: progress to date.New prospects for drug development: the hedgehog pathway revealed. Focus on hematologic malignancies.Multidrug resistance in chronic myeloid leukaemia: how much can we learn from MDR-CML cell lines?Membrane drug transporters and chemoresistance in human pancreatic carcinoma.Hedgehog signaling pathway affects the sensitivity of hepatoma cells to drug therapy through the ABCC1 transporter.Effect of Hedgehog Signaling Pathway Activation on Proliferation of High-Grade Gliomas.Twist1 and Snail link Hedgehog signaling to tumor-initiating cell-like properties and acquired chemoresistance independently of ABC transporters.Targeting of the signal transducer Smo links microRNA-326 to the oncogenic Hedgehog pathway in CD34+ CML stem/progenitor cells.Anti-Cancer Phytometabolites Targeting Cancer Stem CellsB4GALT1 gene knockdown inhibits the hedgehog pathway and reverses multidrug resistance in the human leukemia K562/adriamycin-resistant cell line.Targeting hedgehog-GLI-2 pathway in osteosarcoma.Tracking molecular relapse of chronic myeloid leukemia by measuring Hedgehog signaling status.Novel therapy for therapy-resistant mantle cell lymphoma: multipronged approach with targeting of hedgehog signaling.Hedgehog signaling regulates drug sensitivity by targeting ABC transporters ABCB1 and ABCG2 in epithelial ovarian cancer.Relationship between Hedgehog Signaling Pathway and Drug Resistance of Poorly Differentiated Gliomas.Oncophosphosignaling Favors a Glycolytic Phenotype in Human Drug Resistant Leukemia.Method to Screen Multidrug Transport Inhibitors Using Yeast Overexpressing a Human MDR Transporter.Activation of hedgehog signaling and its association with cisplatin resistance in ovarian epithelial tumors.
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P2860
Hedgehog signaling maintains chemoresistance in myeloid leukemic cells.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
Hedgehog signaling maintains chemoresistance in myeloid leukemic cells.
@en
Hedgehog signaling maintains chemoresistance in myeloid leukemic cells.
@nl
type
label
Hedgehog signaling maintains chemoresistance in myeloid leukemic cells.
@en
Hedgehog signaling maintains chemoresistance in myeloid leukemic cells.
@nl
prefLabel
Hedgehog signaling maintains chemoresistance in myeloid leukemic cells.
@en
Hedgehog signaling maintains chemoresistance in myeloid leukemic cells.
@nl
P2093
P2860
P356
P1433
P1476
Hedgehog signaling maintains chemoresistance in myeloid leukemic cells
@en
P2093
C V Ferreira
G M Fuhler
H L Aberson
K C S Queiroz
R R Ruela-de-Sousa
P2860
P2888
P304
P356
10.1038/ONC.2010.375
P407
P577
2010-08-30T00:00:00Z