Affinity and selectivity of [¹¹C]-(+)-PHNO for the D3 and D2 receptors in the rhesus monkey brain in vivo.
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Selective overexpression of dopamine D3 receptors in the striatum disrupts motivation but not cognition.Dopamine D₃ receptor alterations in cocaine-dependent humans imaged with [¹¹C](+)PHNO.Further characterization of quinpirole-elicited yawning as a model of dopamine D3 receptor activation in male and female monkeys.Estimating endogenous dopamine levels at D2 and D3 receptors in humans using the agonist radiotracer [(11)C]-(+)-PHNOParametric Imaging and Test-Retest Variability of ¹¹C-(+)-PHNO Binding to D₂/D₃ Dopamine Receptors in Humans on the High-Resolution Research Tomograph PET ScannerTargeting the dopamine D3 receptor: an overview of drug design strategies.A preliminary study of dopamine D2/3 receptor availability and social status in healthy and cocaine dependent humans imaged with [(11)C](+)PHNOCharacterization of extrastriatal D2 in vivo specific binding of [¹⁸F](N-methyl)benperidol using PET.Dopamine D3 receptor binding of (18)F-fallypride: Evaluation using in vitro and in vivo PET imaging studies.Dopamine response to psychosocial stress in chronic cannabis users: a PET study with [11C]-+-PHNO.Dopamine D2 and D3 binding in people at clinical high risk for schizophrenia, antipsychotic-naive patients and healthy controls while performing a cognitive taskAge-related changes in binding of the D2/3 receptor radioligand [(11)C](+)PHNO in healthy volunteers.Varenicline-Induced Elevation of Dopamine in Smokers: A Preliminary [(11)C]-(+)-PHNO PET Study.Test-retest reproducibility of [11C]-(+)-propyl-hexahydro-naphtho-oxazin positron emission tomography using the bolus plus constant infusion paradigm.Dopamine D3 Receptor Availability Is Associated with Inflexible Decision Making.Deficits in striatal dopamine release in cannabis dependence.Preferential binding to dopamine D3 over D2 receptors by cariprazine in patients with schizophrenia using PET with the D3/D2 receptor ligand [(11)C]-(+)-PHNOMedication discovery for addiction: translating the dopamine D3 receptor hypothesis.Elevation of dopamine induced by cigarette smoking: novel insights from a [11C]-+-PHNO PET study in humansImaging nicotine- and amphetamine-induced dopamine release in rhesus monkeys with [(11)C]PHNO vs [(11)C]raclopride PET.Exploring the relationship between social attachment and dopamine D2/3 receptor availability in the brains of healthy humans using [11C]-(+)-PHNO.Connectivity-based functional analysis of dopamine release in the striatum using diffusion-weighted MRI and positron emission tomography.Rationale in support of the use of selective dopamine D₃ receptor antagonists for the pharmacotherapeutic management of substance use disorders.Dopamine D₃ receptor antagonism--still a therapeutic option for the treatment of schizophrenia.Dopamine D3 receptor antagonists: a patent review (2007 - 2012).The relationship between subcortical brain volume and striatal dopamine D2/3 receptor availability in healthy humans assessed with [(11) C]-raclopride and [(11) C]-(+)-PHNO PET.Association of Stimulant Use With Dopaminergic Alterations in Users of Cocaine, Amphetamine, or Methamphetamine: A Systematic Review and Meta-analysis.The dopamine D3 receptor, a quarter century later.New imaging probes to track cell fate: reporter genes in stem cell research.Elevated Dopamine D2/3 Receptor Availability in Obese Individuals: A PET Imaging Study with [11C](+)PHNO.Direct and indirect interactions of the dopamine D₃ receptor with glutamate pathways: implications for the treatment of schizophrenia.Brain uptake and distribution of the dopamine D3 /D2 receptor partial agonist [11 C]cariprazine: an in vivo positron emission tomography study in nonhuman primates.Quantitative PET Imaging in Drug Development: Estimation of Target Occupancy.Different effects of chronic THC on the neuroadaptive response of dopamine D2/3 receptor-mediated signaling in roman high- and roman low-avoidance rats.Nigral Stress-Induced Dopamine Release in Clinical High Risk and Antipsychotic-Naïve Schizophrenia.Evaluation of PET Brain Radioligands for Imaging Pancreatic β-Cell Mass: Potential Utility of 11C-PHNO.Surrogate markers for cerebral blood flow correlate with [¹⁸F]-fallypride binding potential at dopamine D(2/3) receptors in human striatum.Regional and source-based patterns of [11C]-(+)-PHNO binding potential reveal concurrent alterations in dopamine D2 and D3 receptor availability in cocaine-use disorder.Amphetamine-Induced Striatal Dopamine Release Measured With an Agonist Radiotracer in Schizophrenia.Determination of receptor occupancy in the presence of mass dose: [11C]GSK189254 PET imaging of histamine H3 receptor occupancy by PF-03654746.
P2860
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P2860
Affinity and selectivity of [¹¹C]-(+)-PHNO for the D3 and D2 receptors in the rhesus monkey brain in vivo.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Affinity and selectivity of [¹¹C]-
@nl
Affinity and selectivity of [¹ ...... e rhesus monkey brain in vivo.
@en
type
label
Affinity and selectivity of [¹¹C]-
@nl
Affinity and selectivity of [¹ ...... e rhesus monkey brain in vivo.
@en
prefLabel
Affinity and selectivity of [¹¹C]-
@nl
Affinity and selectivity of [¹ ...... e rhesus monkey brain in vivo.
@en
P2093
P2860
P356
P1433
P1476
Affinity and selectivity of [¹ ...... e rhesus monkey brain in vivo.
@en
P2093
David Weinzimmer
Eugenii A Rabiner
Jean-Dominique Gallezot
John D Beaver
Krista Fowles
Marc Laruelle
Mark Slifstein
Nabeel Nabulsi
Richard E Carson
Roger N Gunn
P2860
P304
P356
10.1002/SYN.21535
P577
2012-02-24T00:00:00Z