Physiological levels of TNFalpha stimulation induce stochastic dynamics of NF-kappaB responses in single living cells. - Wikidata - awgldk - TriplyDB

Physiological levels of TNFalpha stimulation induce stochastic dynamics of NF-kappaB responses in single living cells.

Physiological levels of TNFalpha stimulation induce stochastic dynamics of NF-kappaB responses in single living cells.

http://www.wikidata.org/entity/Q39675062

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High-throughput analysis of NF-κB dynamics in single cells reveals basal nuclear localization of NF-κB and spontaneous activation of oscillations Signal transduction controls heterogeneous NF-κB dynamics and target gene expression through cytokine-specific refractory states.Quantitative imaging of mammalian transcriptional dynamics: from single cells to whole embryos Automated analysis of NF-κB nuclear translocation kinetics in high-throughput screening The Effect of Solar Irradiated Vibrio cholerae on the Secretion of Pro-Inflammatory Cytokines and Chemokines by the JAWS II Dendritic Cell Line In Vitro Lipopolysaccharide-induced NF-κB nuclear translocation is primarily dependent on MyD88, but TNFα expression requires TRIF and MyD88 Observing single cell NF-κB dynamics under stimulant concentration gradient NF-κB signalling and cell fate decisions in response to a short pulse of tumour necrosis factor.Complex dynamics of transcription regulation.A model for the epigenetic switch linking inflammation to cell transformation: deterministic and stochastic approaches Direct observation of a transient ternary complex during IκBα-mediated dissociation of NF-κB from DNA Modeling the NF-κB mediated inflammatory response predicts cytokine waves in tissue.Ultra high content image analysis and phenotype profiling of 3D cultured micro-tissues.Noise decomposition of intracellular biochemical signaling networks using nonequivalent reporters Statistical ensemble analysis for simulating extrinsic noise-driven response in NF-κB signaling networks.Inactivation of a common OGG1 variant by TNF-alpha in mammalian cells.Single-cell variation leads to population invariance in NF-κB signaling dynamics On the translocation of bacteria and their lipopolysaccharides between blood and peripheral locations in chronic, inflammatory diseases: the central roles of LPS and LPS-induced cell death.Intracellular Information Processing through Encoding and Decoding of Dynamic Signaling Features.Digital signaling decouples activation probability and population heterogeneity.Interrogation of inhibitor of nuclear factor κB α/nuclear factor κB (IκBα/NF-κB) negative feedback loop dynamics: from single cells to live animals in vivo.Irregular Ca(2+) oscillations regulate transcription via cumulative spike duration and spike amplitude Dynamic phosphorylation of RelA on Ser42 and Ser45 in response to TNFα stimulation regulates DNA binding and transcription.Understanding the dynamics of Toll-like Receptor 5 response to flagellin and its regulation by estradiol.Effect of Cell Seeding Density and Inflammatory Cytokines on Adipose Tissue-Derived Stem Cells: an in Vitro Study.Switching of the relative dominance between feedback mechanisms in lipopolysaccharide-induced NF-κB signaling Measurement and modeling of signaling at the single-cell level.Robustness of signal transduction pathways.Topology, dynamics, and heterogeneity in immune signaling.Redefining Signaling Pathways with an Expanding Single-Cell Toolbox.Distinct single-cell signaling characteristics are conferred by the MyD88 and TRIF pathways during TLR4 activation.Quantitative dynamic imaging of immune cell signalling using lentiviral gene transfer.Unraveling cellular pathways contributing to drug-induced liver injury by dynamical modeling.Spontaneous NF-κB activation by autocrine TNFα signaling: a computational analysis Heterogeneous kinetics of AKT signaling in individual cells are accounted for by variable protein concentration.Dynamic NF-κB and E2F interactions control the priority and timing of inflammatory signalling and cell proliferation.Multiplicity of Mathematical Modeling Strategies to Search for Molecular and Cellular Insights into Bacteria Lung Infection.Acting on impulse: dissecting the dynamics of the NFAT transcriptional response A20/TNFAIP3 Discriminates Tumor Necrosis Factor (TNF)-Induced NF-κB from JNK Pathway Activation in Hepatocytes.SOCS3 dictates the transition of divergent time-phased events in granulocyte TNF-α signaling.

P2860

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P2860

Physiological levels of TNFalpha stimulation induce stochastic dynamics of NF-kappaB responses in single living cells.

http://www.wikidata.org/entity/Q39675062

description

2010 nî lūn-bûn

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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2010年论文

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2010年论文

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name

Physiological levels of TNFalp ...... ponses in single living cells.

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Physiological levels of TNFalp ...... ponses in single living cells.

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type

label

Physiological levels of TNFalp ...... ponses in single living cells.

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Physiological levels of TNFalp ...... ponses in single living cells.

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prefLabel

Physiological levels of TNFalp ...... ponses in single living cells.

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Physiological levels of TNFalp ...... ponses in single living cells.

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Journal of Cell Science

P1476

Physiological levels of TNFalp ...... ponses in single living cells.

@en

P2093

Caroline A Horton

http://www.w3.org/2001/XMLSchema#string

Claire V Harper

http://www.w3.org/2001/XMLSchema#string

Dan J Woodcock

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David A Rand

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David A Turner

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David E Nelson

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Michael R H White

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Pawel Paszek

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Yunjiao Wang

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P2860

TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways

The TNF receptor 1-associated protein TRADD signals cell death and NF-kappa B activation

TNF-dependent recruitment of the protein kinase RIP to the TNF receptor-1 signaling complex

Sustained oscillations of NF-kappaB produce distinct genome scanning and gene expression profiles

Crystal structure of sTALL-1 reveals a virus-like assembly of TNF family ligands

Recruitment of the IKK signalosome to the p55 TNF receptor: RIP and A20 bind to NEMO (IKKgamma) upon receptor stimulation

Direct phosphorylation of IkappaB by IKKalpha and IKKbeta: discrimination between free and NF-kappaB-bound substrate

Oscillations in NF-kappaB signaling control the dynamics of gene expression

Shared principles in NF-kappaB signaling

Calcium oscillations increase the efficiency and specificity of gene expression

P304

2834-2843

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scholarly article

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10.1242/JCS.069641

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P433

Pt 16

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P478

123

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2010-07-27T00:00:00Z

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20663918

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2915884

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