Strategies for selecting recombinant CHO cell lines for cGMP manufacturing: realizing the potential in bioreactors.
about
Combination of FACS and homologous recombination for the generation of stable and high-expression engineered cell linesIn situ monitoring of intracellular glucose and glutamine in CHO cell cultureComparative evaluation of heterologous production systems for recombinant pulmonary surfactant protein D.Cell line development for biomanufacturing processes: recent advances and an outlook.The enhancement of antibody concentration and achievement of high cell density CHO cell cultivation by adding nucleoside.Methionine sulfoximine supplementation enhances productivity in GS-CHOK1SV cell lines through glutathione biosynthesis.High-throughput screening and selection of mammalian cells for enhanced protein production.A hybrid approach identifies metabolic signatures of high-producers for chinese hamster ovary clone selection and process optimization.An ultra scale-down approach identifies host cell protein differences across a panel of mAb producing CHO cell line variants.Screening and assessment of performance and molecule quality attributes of industrial cell lines across different fed-batch systems.Recombinase-mediated cassette exchange (RMCE) for monoclonal antibody expression in the commercially relevant CHOK1SV cell line.Microarray profiling of preselected CHO host cell subclones identifies gene expression patterns associated with increased production capacity.Metabolite profiling of CHO cells: Molecular reflections of bioprocessing effectiveness.Chinese hamster ovary K1 host cell enables stable cell line development for antibody molecules which are difficult to express in DUXB11-derived dihydrofolate reductase deficient host cell.Recombinant human butyrylcholinesterase as a new-age bioscavenger drug: development of the expression system.An empirical modeling platform to evaluate the relative control discrete CHO cell synthetic processes exert over recombinant monoclonal antibody production process titer.mTORC1 signalling and eIF4E/4E-BP1 translation initiation factor stoichiometry influence recombinant protein productivity from GS-CHOK1 cells.Functional heterogeneity and heritability in CHO cell populations.A strategy for clone selection under different production conditions.The emerging role of systems biology for engineering protein production in CHO cells.
P2860
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P2860
Strategies for selecting recombinant CHO cell lines for cGMP manufacturing: realizing the potential in bioreactors.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
Strategies for selecting recom ...... the potential in bioreactors.
@en
Strategies for selecting recom ...... the potential in bioreactors.
@nl
type
label
Strategies for selecting recom ...... the potential in bioreactors.
@en
Strategies for selecting recom ...... the potential in bioreactors.
@nl
prefLabel
Strategies for selecting recom ...... the potential in bioreactors.
@en
Strategies for selecting recom ...... the potential in bioreactors.
@nl
P2093
P356
P1476
Strategies for selecting recom ...... the potential in bioreactors.
@en
P2093
Alan J Dickson
Alison J Porter
Andrew J Racher
P304
P356
10.1002/BTPR.442
P577
2010-09-01T00:00:00Z